RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 604 | 2014 |
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells SL Masters, M Gerlic, D Metcalf, S Preston, M Pellegrini, JA O’Donnell, ... Immunity 37 (6), 1009-1023, 2012 | 324 | 2012 |
Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1 BA Croker, JA O'Donnell, CJ Nowell, D Metcalf, G Dewson, KJ Campbell, ... Proceedings of the National Academy of Sciences 108 (32), 13135-13140, 2011 | 144 | 2011 |
Gut Microbiota and Their Metabolites in Stroke: A Double-Edged Sword A Peh, JA O’Donnell, BRS Broughton, FZ Marques Stroke 53 (5), 1788-1801, 2022 | 116 | 2022 |
Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis VS Raman, A Bhatia, A Picone, J Whittle, HR Bailor, J O’Donnell, ... The Journal of Immunology 185 (3), 1701-1710, 2010 | 110 | 2010 |
Regulation of interleukin‐1β by interferon‐γ is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin‐17 production SL Masters, LA Mielke, AL Cornish, CE Sutton, J O'donnell, LH Cengia, ... EMBO reports 11 (8), 640-646, 2010 | 96 | 2010 |
MyD88 and TRIF synergistic interaction is required for TH1‐cell polarization with a synthetic TLR4 agonist adjuvant MT Orr, MS Duthie, HP Windish, EA Lucas, JA Guderian, TE Hudson, ... European journal of immunology 43 (9), 2398-2408, 2013 | 95 | 2013 |
The gut microbiome and hypertension JA O’Donnell, T Zheng, G Meric, FZ Marques Nature Reviews Nephrology 19 (3), 153-167, 2023 | 93 | 2023 |
The Gut Microbiome of Heart Failure With Preserved Ejection Fraction AL Beale, JA O’Donnell, ME Nakai, S Nanayakkara, D Vizi, K Carter, ... Journal of the American Heart Association 10 (13), e020654, 2021 | 87 | 2021 |
RIP kinase 1–dependent endothelial necroptosis underlies systemic inflammatory response syndrome M Zelic, JE Roderick, JA O’Donnell, J Lehman, SE Lim, HP Janardhan, ... The Journal of clinical investigation 128 (5), 2064-2075, 2018 | 85 | 2018 |
IL‐6 promotes acute and chronic inflammatory disease in the absence of SOCS3 BA Croker, H Kiu, M Pellegrini, J Toe, S Preston, D Metcalf, JA O'donnell, ... Immunology & Cell Biology 90 (1), 124-129, 2012 | 75 | 2012 |
Pyroptotic death storms and cytopenia BA Croker, JA O’Donnell, M Gerlic Current opinion in immunology 26, 128-137, 2014 | 65 | 2014 |
Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset KL Graham, JA O'Donnell, Y Tan, N Sanders, EM Carrington, J Allison, ... Journal of virology 81 (12), 6446-6458, 2007 | 63 | 2007 |
Insight toward early diagnosis of leprosy through analysis of the developing antibody responses of Mycobacterium leprae-infected armadillos MS Duthie, RW Truman, W Goto, J O'Donnell, MN Hay, JS Spencer, ... Clinical and vaccine immunology 18 (2), 254-259, 2011 | 58 | 2011 |
Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease BA Croker, RS Lewis, JJ Babon, JD Mintern, DE Jenne, D Metcalf, ... The Journal of Immunology 186 (2), 1131-1139, 2011 | 52 | 2011 |
Rodent models of hypertension HA Jama, RR Muralitharan, C Xu, JA O'Donnell, M Bertagnolli, ... British Journal of Pharmacology 179 (5), 918-937, 2022 | 46 | 2022 |
Fas regulates neutrophil lifespan during viral and bacterial infection JA O’Donnell, CL Kennedy, M Pellegrini, CJ Nowell, JG Zhang, ... Journal of Leucocyte Biology 97 (2), 321-326, 2015 | 46 | 2015 |
Ptpn6 inhibits caspase-8-and Ripk3/Mlkl-dependent inflammation M Speir, CJ Nowell, AA Chen, JA O’Donnell, IS Shamie, PR Lakin, ... Nature Immunology 21 (1), 54-64, 2020 | 44 | 2020 |
Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity JA O’Donnell, J Lehman, JE Roderick, D Martinez-Marin, M Zelic, ... The Journal of Immunology 200 (2), 737-748, 2018 | 39 | 2018 |
Vaccination with the ML0276 antigen reduces local inflammation but not bacterial burden during experimental Mycobacterium leprae infection VS Raman, J O'Donnell, HR Bailor, W Goto, R Lahiri, TP Gillis, SG Reed, ... Infection and immunity 77 (12), 5623-5630, 2009 | 33 | 2009 |