‪Pedro de Sena Murteira Pinheiro‬

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Carlos Alberto Manssour FragaProfessor de Farmacologia e Química Medicinal, Universidade Federal do Rio de JaneiroVerified email at ccsdecania.ufrj.br
Daniel Alencar RodriguesRoyal College of Surgeons in IrelandVerified email at rcsi.com
Carlos Mauricio R. Sant AnnaProfessor Titular do Departamento de Química, Universidade Federal Rural do Rio de JaneiroVerified email at ufrrj.br
Dr. Sreekanth ThotaProfessor (Pharmaceutical Chemistry & Medicinal Chemistry)Verified email at cdts.fiocruz.br
Eliezer J. BarreiroProfessor de Química Medicinal, Universidade Federal do Rio de JaneiroVerified email at ccsdecania.ufrj.br
Maria Laura BolognesiAlma Mater Studiorum - University of BolognaVerified email at unibo.it
Lídia Moreira LimaProfessora Titular, Universidade Federal do Rio de JaneiroVerified email at icb.ufrj.br
Marina Amaral AlvesAssistant Professor, Federal University of Rio de Janeiro, BrazilVerified email at iq.ufrj.br
Fabio Furlan FerreiraCenter for Natural and Human Sciences - CCNH, Federal University of ABC - UFABCVerified email at ufabc.edu.br
Patricia Dias FernandesProfessor de Farmacologia, UFRJVerified email at icb.ufrj.br
Christian F.W. BeckerUniversity of Vienna, Institute of Biological ChemistryVerified email at univie.ac.at
Hugo VerliProfessor de Bioinformática, Centro de Biotecnologia, Universidade Federal do Rio Grande do SulVerified email at cbiot.ufrgs.br
Roberta TeschPostdoctoral Fellow, Goethe UniversitätVerified email at pharmchem.uni-frankfurt.de
Marcelo D. PolêtoPostdoctoral Associate, Virginia TechVerified email at vt.edu
Lucas Silva FrancoUniversidade Federal do Rio de JaneiroVerified email at ufrj.br
Elisa UliassiUniversity of BolognaVerified email at unibo.it
Manuela BartoliniUniversity of BolognaVerified email at unibo.it
Alvicler MagalhãesUFRJVerified email at iq.ufrj.br
Thales KronenbergerUniversity Hospital of Tübingen - DZIF Tübingen Partner siteVerified email at uni-tuebingen.de
Jéssica GuedesLund UniversityVerified email at med.lu.se

Pedro de Sena Murteira Pinheiro

Assistant Professor, Federal University of Rio de Janeiro

Verified email at ufrj.br

Medicinal Chemistry Organic Chemistry Theoretical Chemistry Molecular Modeling Pharmacology


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N-Acylhydrazones as drugs S Thota, DA Rodrigues, PSM Pinheiro, LM Lima, CAM Fraga, EJ Barreiro Bioorganic & medicinal chemistry letters 28 (17), 2797-2806, 2018	169	2018
From combinations to multitarget‐directed ligands: A continuum in Alzheimer's disease polypharmacology C Albertini, A Salerno, P de Sena Murteira Pinheiro, ML Bolognesi Medicinal Research Reviews 41 (5), 2606-2633, 2021	101	2021
Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities DA Rodrigues, PSM Pinheiro, FS Sagrillo, ML Bolognesi, CAM Fraga Medicinal Research Reviews 40 (6), 2177-2211, 2020	43	2020
Design, Synthesis, and Pharmacological Evaluation of First‐in‐Class Multitarget N‐Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors DA Rodrigues, FS Guerra, FS Sagrillo, P de Sena M. Pinheiro, MA Alves, ... ChemMedChem 15 (6), 539-551, 2020	34	2020
The Use of Conformational Restriction in Medicinal Chemistry P de Sena M Pinheiro, DA Rodrigues, R do Couto Maia, S Thota, ... Current topics in medicinal chemistry 19 (19), 1712-1733, 2019	30	2019
Multitarget inhibition of histone deacetylase (HDAC) and phosphatidylinositol‐3‐kinase (PI3K): Current and future prospects DA Rodrigues, PSM Pinheiro, CAM Fraga ChemMedChem 16 (3), 448-457, 2021	18	2021
Theoretical and experimental characterization of 1, 4-N⋯ S σ-hole intramolecular interactions in bioactive N-acylhydrazone derivatives PSM Pinheiro, DA Rodrigues, MA Alves, LW Tinoco, GB Ferreira, ... New Journal of Chemistry 42 (1), 497-505, 2018	16	2018
HÁ ALGO NOVO NO RECONHECIMENTO MOLECULAR APLICADO À QUÍMICA MEDICINAL? HH Fokoue, PSM Pinheiro, CAM Fraga, CMR Sant’Anna Química Nova 43, 78-89, 2020	15	2020
Structural basis for the agonist action at free fatty acid receptor 1 (FFA1R or GPR40) DA Rodrigues, PSM Pinheiro, TTSC Ferreira, S Thota, CAM Fraga Chemical biology & drug design 91 (3), 668-680, 2018	15	2018
An Unusual Intramolecular Halogen Bond Guides Conformational Selection R Tesch, C Becker, MP Müller, ME Beck, L Quambusch, M Getlik, ... Angewandte Chemie International Edition 57 (31), 9970-9975, 2018	13	2018
Turning Donepezil into a Multi‐Target‐Directed Ligand through a Merging Strategy R Perone, C Albertini, E Uliassi, F Di Pietri, P de Sena Murteira Pinheiro, ... ChemMedChem 16 (1), 187-198, 2021	12	2021
Design, Synthesis, Experimental and Theoretical Characterization of a New Multitarget 2-Thienyl-N-Acylhydrazone Derivative I Bastos, P Pinheiro, F Costa, M Rocha, C Sant’Anna, D Braz, E Souza, ... Pharmaceuticals 11 (4), 119, 2018	8	2018
Modeling zinc‐oxygen coordination in histone deacetylase: A comparison of semiempirical methods performance PSM Pinheiro, DA Rodrigues, CMR Sant'Anna, CAM Fraga International Journal of Quantum Chemistry 118 (21), e25720, 2018	6	2018
The Magic Methyl and Its Tricks in Drug Discovery and Development PSM Pinheiro, LS Franco, CAM Fraga Pharmaceuticals 16 (8), 1157, 2023	5	2023
IS THERE ANYTHING NEW ABOUT THE MOLECULAR RECOGNITION APPLIED TO MEDICINAL CHEMISTRY? HH Fokoue, PSM Pinheiro, CAM Fraga, CMR Sant’Anna Química Nova 43, 78-89, 2020	3	2020
Structure–property relationship studies of 3-acyl-substituted furans: the serendipitous identification and characterization of a new non-classical hydrogen bond donor moiety DA Rodrigues, MP Pedro de Sena, FS Sagrillo, MCR Freitas, MA Alves, ... New Journal of Chemistry 44 (26), 10994-11005, 2020	3	2020
Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the … TT da Silva Cunha, RR Silva, DA Rodrigues, P de Sena Murteira Pinheiro, ... Biomolecules 12 (8), 1112, 2022	2	2022
Methyl Effect on the Metabolism, Chemical Stability, and Permeability Profile of Bioactive N-Sulfonylhydrazones JS Guedes, TR Carneiro, PSM Pinheiro, CAM Fraga, CMR Sant′ Anna, ... ACS omega 7 (43), 38752-38765, 2022	1	2022
Investigating the Molecular Basis for the Selective Inhibition of Aldehyde Dehydrogenase 2 by the Isoflavonoid Daidzin TT da Silva Cunha, FR de Souza, P de Sena Murteira Pinheiro, ... CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2020	1	2020
Molecular hybridization: a powerful tool for multitarget drug discovery P de Sena Murteira Pinheiro, LS Franco, TL Montagnoli, CAM Fraga Expert Opinion on Drug Discovery 19 (4), 451-470, 2024		2024

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