Robert Brink
Robert Brink
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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
CC Goodnow, J Crosbie, S Adelstein, TB Lavoie, SJ Smith-Gill, RA Brink, ...
Nature 334 (6184), 676-682, 1988
IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis
JE Vince, WWL Wong, N Khan, R Feltham, D Chau, AU Ahmed, ...
Cell 131 (4), 682-693, 2007
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
SB Hartley, J Crosbie, R Brink, AB Kantor, A Basten, CC Goodnow
Nature 353 (6346), 765-769, 1991
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
M Thien, TG Phan, S Gardam, M Amesbury, A Basten, F Mackay, R Brink
Immunity 20 (6), 785-798, 2004
Induction of self-tolerance in mature peripheral B lymphocytes
CC Goodnow, J Crosbie, H Jorgensen, RA Brink, A Basten
Nature 342 (6248), 385-391, 1989
Follicular helper T cells are required for systemic autoimmunity
MA Linterman, RJ Rigby, RK Wong, D Yu, R Brink, JL Cannons, ...
Journal of Experimental Medicine 206 (3), 561-576, 2009
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
DT Avery, SL Kalled, JI Ellyard, C Ambrose, SA Bixler, M Thien, R Brink, ...
The Journal of clinical investigation 112 (2), 286-297, 2003
Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
D Paus, TG Phan, TD Chan, S Gardam, A Basten, R Brink
Journal of experimental medicine 203 (4), 1081-1091, 2006
The good, the bad and the ugly — TFH cells in human health and disease
SG Tangye, CS Ma, R Brink, EK Deenick
Nature Reviews Immunology 13 (6), 412-426, 2013
Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure
J He, LM Tsai, YA Leong, X Hu, CS Ma, N Chevalier, X Sun, ...
Immunity 39 (4), 770-781, 2013
Control systems and decision making for antibody production
CC Goodnow, CG Vinuesa, KL Randall, F Mackay, R Brink
Nature immunology 11 (8), 681-688, 2010
High affinity germinal center B cells are actively selected into the plasma cell compartment
TG Phan, D Paus, TD Chan, ML Turner, SL Nutt, A Basten, R Brink
Journal of Experimental Medicine 203 (11), 2419-2424, 2006
B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
DT Avery, EK Deenick, CS Ma, S Suryani, N Simpson, GY Chew, ...
Journal of Experimental Medicine 207 (1), 155-171, 2010
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling
EK Deenick, A Chan, CS Ma, D Gatto, PL Schwartzberg, R Brink, ...
Immunity 33 (2), 241-253, 2010
Breakdown of self-tolerance in anergic B lymphocytes
CC Goodnow, R Brink, E Adams
Nature 352 (6335), 532-536, 1991
Follicular dendritic cells emerge from ubiquitous perivascular precursors
NJ Krautler, V Kana, J Kranich, Y Tian, D Perera, D Lemm, P Schwarz, ...
Cell 150 (1), 194-206, 2012
B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
F Mackay, PA Silveira, R Brink
Current opinion in immunology 19 (3), 327-336, 2007
Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4
K Ochiai, M Maienschein-Cline, G Simonetti, J Chen, R Rosenthal, ...
Immunity 38 (5), 918-929, 2013
Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses
D Gatto, D Paus, A Basten, CR Mackay, R Brink
Immunity 31 (2), 259-269, 2009
Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
PP Chang, P Barral, J Fitch, A Pratama, CS Ma, A Kallies, JJ Hogan, ...
Nature immunology 13 (1), 35-43, 2012
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