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Christopher A Cottrell
Christopher A Cottrell
Verified email at scripps.edu
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Cited by
Year
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
J Pallesen, N Wang, KS Corbett, D Wrapp, RN Kirchdoerfer, HL Turner, ...
Proceedings of the National Academy of Sciences 114 (35), E7348-E7357, 2017
10542017
Pre-fusion structure of a human coronavirus spike protein
RN Kirchdoerfer, CA Cottrell, N Wang, J Pallesen, HM Yassine, HL Turner, ...
Nature 531 (7592), 118-121, 2016
8082016
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp, HL Turner, CA Cottrell, ...
Scientific reports 8 (1), 15701, 2018
5122018
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ...
Cell 177 (5), 1153-1171. e28, 2019
2922019
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches
M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ...
Immunity 46 (6), 1073-1088. e6, 2017
2912017
Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
G Ozorowski, J Pallesen, N de Val, D Lyumkis, CA Cottrell, JL Torres, ...
Nature 547 (7663), 360-363, 2017
2342017
A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure
JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ...
Immunity 46 (4), 690-702, 2017
2322017
Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies
LE McCoy, MJ van Gils, G Ozorowski, T Messmer, B Briney, JE Voss, ...
Cell reports 16 (9), 2327-2338, 2016
2302016
Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization
M Bianchi, HL Turner, B Nogal, CA Cottrell, D Oyen, M Pauthner, ...
Immunity 49 (2), 288-300. e8, 2018
1732018
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, ...
Nature Communications 10 (1), 4272, 2019
1522019
Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization
AT de la Pena, JP Julien, SW de Taeye, F Garces, M Guttman, ...
Cell reports 20 (8), 1805-1817, 2017
1462017
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
MJ Van Gils, TLGM Van Den Kerkhof, G Ozorowski, CA Cottrell, D Sok, ...
Nature microbiology 2 (2), 1-10, 2016
1432016
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding
DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ...
Nature communications 8 (1), 1655, 2017
1402017
Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers
MG Pauthner, JP Nkolola, C Havenar-Daughton, B Murrell, SM Reiss, ...
Immunity 50 (1), 241-252. e6, 2019
1392019
Vaccination with glycan-modified HIV NFL envelope trimer-liposomes elicits broadly neutralizing antibodies to multiple sites of vulnerability
V Dubrovskaya, K Tran, G Ozorowski, J Guenaga, R Wilson, S Bale, ...
Immunity 51 (5), 915-929. e7, 2019
1212019
Structure of the human volume regulated anion channel
JM Kefauver, K Saotome, AE Dubin, J Pallesen, CA Cottrell, SM Cahalan, ...
Elife 7, e38461, 2018
1142018
Structures of Ebola virus GP and sGP in complex with therapeutic antibodies
J Pallesen, CD Murin, N De Val, CA Cottrell, KM Hastie, HL Turner, ...
Nature microbiology 1 (9), 1-9, 2016
1072016
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
PJ Klasse, TJ Ketas, CA Cottrell, G Ozorowski, G Debnath, D Camara, ...
PLoS pathogens 14 (2), e1006913, 2018
1052018
Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers
RP Ringe, A Yasmeen, G Ozorowski, EP Go, LK Pritchard, M Guttman, ...
Journal of virology 89 (23), 12189-12210, 2015
1032015
Vaccination induces HIV broadly neutralizing antibody precursors in humans
DJ Leggat, KW Cohen, JR Willis, WJ Fulp, AC Decamp, O Kalyuzhniy, ...
Science 378 (6623), eadd6502, 2022
882022
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