John Upham
John Upham
Professor of Respiratory Medicine, The University of Queensland
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Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial
PG Gibson, IA Yang, JW Upham, PN Reynolds, S Hodge, AL James, ...
The Lancet 390 (10095), 659-668, 2017
Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology
SL Taylor, LEX Leong, JM Choo, S Wesselingh, IA Yang, JW Upham, ...
Journal of Allergy and Clinical Immunology 141 (1), 94-103. e15, 2018
Contemporaneous maturation of immunologic and respiratory functions during early childhood: implications for development of asthma prevention strategies
PG Holt, JW Upham, PD Sly
Journal of Allergy and Clinical Immunology 116 (1), 16-24, 2005
Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge
FL Jahnsen, ED Moloney, T Hogan, JW Upham, CM Burke, PG Holt
Thorax 56 (11), 823-826, 2001
Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial
WW Busse, ER Bleecker, JM FitzGerald, GT Ferguson, P Barker, ...
The lancet respiratory medicine 7 (1), 46-59, 2019
Development of interleukin-12-producing capacity throughout childhood
JW Upham, PT Lee, BJ Holt, T Heaton, SL Prescott, MJ Sharp, PD Sly, ...
Infection and immunity 70 (12), 6583-6588, 2002
Full blood count parameters for the detection of asthma inflammatory phenotypes
XY Zhang, JL Simpson, H Powell, IA Yang, JW Upham, PN Reynolds, ...
Clinical & experimental allergy 44 (9), 1137-1145, 2014
Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma
JL Simpson, J Daly, KJ Baines, IA Yang, JW Upham, PN Reynolds, ...
European Respiratory Journal 47 (3), 792-800, 2016
TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide
MK Tulic, RJ Hurrelbrink, CM Prêle, IA Laing, JW Upham, P Le Souef, ...
The Journal of Immunology 179 (1), 132-140, 2007
Protracted bacterial bronchitis: the last decade and the road ahead
AB Chang, JW Upham, IB Masters, GR Redding, PG Gibson, JM Marchant, ...
Pediatric Pulmonology 51 (3), 225-242, 2016
Functional maturation of CD4+ CD25+ CTLA4+ CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens
CA Thornton, JW Upham, ME Wikström, BJ Holt, GP White, MJ Sharp, ...
The Journal of Immunology 173 (5), 3084-3092, 2004
Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide
ST Yerkovich, ME Wikström, D Suriyaarachchi, SL Prescott, JW Upham, ...
Pediatric research 62 (5), 547-552, 2007
Reduced soluble receptor for advanced glycation end-products in COPD
DJ Smith, ST Yerkovich, MA Towers, ML Carroll, R Thomas, JW Upham
European Respiratory Journal 37 (3), 516-522, 2011
Treatable traits can be identified in a severe asthma registry and predict future exacerbations
VM McDonald, SA Hiles, K Godbout, ES Harvey, GB Marks, M Hew, ...
Respirology 24 (1), 37-47, 2019
Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma
SL Taylor, LEX Leong, FM Mobegi, JM Choo, S Wesselingh, IA Yang, ...
American journal of respiratory and critical care medicine 200 (3), 309-317, 2019
Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis
DF Wurzel, JM Marchant, ST Yerkovich, JW Upham, HL Petsky, ...
Chest 150 (5), 1101-1108, 2016
Inhalant allergen‐specific T‐cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum‐free medium
JW Upham, BJ Holt, MJ Baron‐Hay, A Yabuhara, BJ Hales, WR Thomas, ...
Clinical & Experimental Allergy 25 (7), 634-642, 1995
T‐cell “priming” against environmental allergens in human neonates: sequential deletion of food antigen reactivity during infancy with concomitant expansion of responses to …
PG Holt, P O'keeffe, BJ Holt, JW Upham, MJ Baron‐Hay, C Suphioglu, ...
Pediatric Allergy and Immunology 6 (2), 85-90, 1995
Mepolizumab effectiveness and identification of super-responders in severe asthma
ES Harvey, D Langton, C Katelaris, S Stevens, CS Farah, A Gillman, ...
European Respiratory Journal 55 (5), 2020
Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma
S Navarro, DA Pickering, IB Ferreira, L Jones, S Ryan, S Troy, A Leech, ...
Science translational medicine 8 (362), 362ra143-362ra143, 2016
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