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Anthony M Lynch
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How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop
D Kirkland, S Pfuhler, D Tweats, M Aardema, R Corvi, F Darroudi, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 628 (1 …, 2007
4742007
CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans
AR Boobis, AM Lynch, S Murray, R de la Torre, A Solans, M Farré, ...
Cancer research 54 (1), 89-94, 1994
3221994
Site-specific mutagenesis: retrospective and prospective
B Singer
Carcinogenesis 12, 949-955, 1991
2381991
The in vivo Pig-a assay: a report of the International Workshop on Genotoxicity Testing (IWGT) Workgroup
BB Gollapudi, AM Lynch, RH Heflich, SD Dertinger, VN Dobrovolsky, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, 23-35, 2015
1552015
Early events in the mammalian response to DNA double-strand breaks
LC Riches, AM Lynch, NJ Gooderham
Mutagenesis 23 (5), 331-339, 2008
1432008
Intra-and interindividual variability in systemic exposure in humans to 2-amino-3, 8-dimethylimidazo [4, 5-f] quinoxaline and 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine …
AM Lynch, MG Knize, AR Boobis, NJ Gooderham, DS Davies, S Murray
Cancer Research 52 (22), 6216-6223, 1992
1351992
Quantification of the carcinogens 2-amino-3, 8-dimethyl-and 2-amino-3, 4, 8-trimethylimidazo [4, 5-f] quinoxaline and 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine in food …
S Murray, AM Lynch, MG Knize, NJ Gooderham
Journal of Chromatography B: Biomedical Sciences and Applications 616 (2 …, 1993
1311993
Genotoxicity screening via the γH2AX by flow assay
DJ Smart, KP Ahmedi, JS Harvey, AM Lynch
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 715 (1 …, 2011
1252011
Investigations into the concept of a threshold for topoisomerase inhibitor‐induced clastogenicity
A Lynch, J Harvey, M Aylott, E Nicholas, M Burman, A Siddiqui, S Walker, ...
Mutagenesis 18 (4), 345-353, 2003
1162003
New and emerging technologies for genetic toxicity testing
AM Lynch, JC Sasaki, R Elespuru, D Jacobson‐Kram, V Thybaud, ...
Environmental and molecular mutagenesis 52 (3), 205-223, 2011
1132011
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I …
D Kirkland, E Zeiger, F Madia, N Gooderham, P Kasper, A Lynch, T Morita, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 775, 55-68, 2014
1112014
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay
SM Bryce, SL Avlasevich, JC Bemis, M Lukamowicz, A Elhajouji, ...
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 650 (2 …, 2008
1072008
The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing–The report of an ECVAM–EFPIA workshop
M Ceridono, P Tellner, D Bauer, J Barroso, N Alépée, R Corvi, ...
Regulatory Toxicology and Pharmacology 63 (3), 480-488, 2012
992012
Assessing human risk to heterocyclic amines
NJ Gooderham, S Murray, AM Lynch, M Yadollahi-Farsani, K Zhao, ...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 376 (1 …, 1997
921997
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens
AM Lynch, JM Parry
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 287 (1 …, 1993
921993
Food-derived heterocyclic amine mutagens: variable metabolism and significance to humans
NJ Gooderham, S Murray, AM Lynch, M Yadollahi-Farsani, K Zhao, ...
Drug metabolism and disposition 29 (4), 529-534, 2001
872001
Safety and efficacy of ozanezumab in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled, phase 2 trial
V Meininger, A Genge, LH van den Berg, W Robberecht, A Ludolph, ...
The Lancet Neurology 16 (3), 208-216, 2017
802017
Flow cytometric enumeration of micronucleated reticulocytes: high transferability among 14 laboratories
DK Torous, NE Hall, SD Dertinger, MS Diehl, AH Illi‐Love, K Cederbrant, ...
Environmental and molecular mutagenesis 38 (1), 59-68, 2001
792001
International Pig‐a gene mutation assay trial: Evaluation of transferability across 14 laboratories
SD Dertinger, S Phonethepswath, P Weller, J Nicolette, J Murray, ...
Environmental and molecular mutagenesis 52 (9), 690-698, 2011
772011
Flow cytometric analysis of micronuclei in mammalian cell cultures: past, present and future
S Avlasevich, S Bryce, M De Boeck, A Elhajouji, F Van Goethem, A Lynch, ...
Mutagenesis 26 (1), 147-152, 2011
722011
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