Characterization of the kynurenine pathway in human neurons GJ Guillemin, KM Cullen, CK Lim, GA Smythe, B Garner, V Kapoor, ... Journal of Neuroscience 27 (47), 12884-12892, 2007 | 272 | 2007 |
Connecting inflammation with glutamate agonism in suicidality S Erhardt, CK Lim, KR Linderholm, S Janelidze, D Lindqvist, ... Neuropsychopharmacology 38 (5), 743-752, 2013 | 250 | 2013 |
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality C Bay-Richter, KR Linderholm, CK Lim, M Samuelsson, ... Brain, behavior, and immunity 43, 110-117, 2015 | 209 | 2015 |
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases MD Lovelace, B Varney, G Sundaram, MJ Lennon, CK Lim, K Jacobs, ... Neuropharmacology 112, 373-388, 2017 | 165 | 2017 |
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells WS Kim, GJ Guillemin, EN Glaros, CK Lim, B Garner Neuroreport 17 (9), 891-896, 2006 | 134 | 2006 |
Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton RC Dale, EM Tantsis, V Merheb, RYA Kumaran, N Sinmaz, ... Neurology-Neuroimmunology Neuroinflammation 1 (1), 2014 | 125 | 2014 |
Expression of tryptophan 2, 3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain W Wu, JA Nicolazzo, L Wen, R Chung, R Stankovic, SS Bao, CK Lim, ... PloS one 8 (4), e59749, 2013 | 108 | 2013 |
Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression CK Lim, A Bilgin, DB Lovejoy, V Tan, S Bustamante, BV Taylor, ... Scientific reports 7 (1), 1-9, 2017 | 106 | 2017 |
NAD deficiency, congenital malformations, and niacin supplementation H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ... New England Journal of Medicine 377 (6), 544-552, 2017 | 102 | 2017 |
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation L Brundin, CM Sellgren, CK Lim, J Grit, E Pålsson, M Landen, ... Translational psychiatry 6 (8), e865-e865, 2016 | 92 | 2016 |
Involvement of the kynurenine pathway in human glioma pathophysiology S Adams, C Teo, KL McDonald, A Zinger, S Bustamante, CK Lim, ... PloS one 9 (11), e112945, 2014 | 91 | 2014 |
Understanding the role of the kynurenine pathway in human breast cancer immunobiology B Heng, CK Lim, DB Lovejoy, A Bessede, L Gluch, GJ Guillemin Oncotarget 7 (6), 6506, 2016 | 84 | 2016 |
Expression of the kynurenine pathway in human peripheral blood mononuclear cells: implications for inflammatory and neurodegenerative disease SP Jones, NF Franco, B Varney, G Sundaram, DA Brown, J De Bie, ... PloS one 10 (6), e0131389, 2015 | 73 | 2015 |
Current evidence for a role of the kynurenine pathway of tryptophan metabolism in multiple sclerosis MD Lovelace, B Varney, G Sundaram, NF Franco, ML Ng, S Pai, CK Lim, ... Frontiers in immunology 7, 246, 2016 | 71 | 2016 |
Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease CK Lim, FJ Fernandez-Gomez, N Braidy, C Estrada, C Costa, S Costa, ... Progress in neurobiology 155, 76-95, 2017 | 66 | 2017 |
Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia J Kindler, CK Lim, CS Weickert, D Boerrigter, C Galletly, D Liu, KR Jacobs, ... Molecular psychiatry 25 (11), 2860-2872, 2020 | 56 | 2020 |
Does escitalopram reduce neurotoxicity in major depression? A Halaris, AM Myint, V Savant, E Meresh, E Lim, G Guillemin, ... Journal of psychiatric research 66, 118-126, 2015 | 53 | 2015 |
Altered kynurenine pathway metabolism in autism: implication for immune‐induced glutamatergic activity CK Lim, MM Essa, R de Paula Martins, DB Lovejoy, AA Bilgin, MI Waly, ... Autism Research 9 (6), 621-631, 2016 | 50 | 2016 |
Understanding the roles of the kynurenine pathway in multiple sclerosis progression CK Lim, BJ Brew, G Sundaram, GJ Guillemin International Journal of Tryptophan Research 3, IJTR. S4294, 2010 | 50 | 2010 |
Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans EB Yan, T Frugier, CK Lim, B Heng, G Sundaram, M Tan, JV Rosenfeld, ... Journal of neuroinflammation 12 (1), 1-17, 2015 | 49 | 2015 |