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Alyssa L. Kennedy
Alyssa L. Kennedy
Dana-Farber/Boston Children's Hospital Cancer and Blood Disorders Center
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
X Ye, B Zerlanko, A Kennedy, G Banumathy, R Zhang, PD Adams
Molecular cell 27 (2), 183-196, 2007
2442007
Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis
AL Kennedy, JP Morton, I Manoharan, DM Nelson, NB Jamieson, ...
Molecular cell 42 (1), 36-49, 2011
2262011
Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias
CG Mullighan, A Kennedy, X Zhou, I Radtke, LA Phillips, SA Shurtleff, ...
Leukemia 21 (9), 2000-2009, 2007
2122007
Genetic predisposition to MDS: clinical features and clonal evolution
AL Kennedy, A Shimamura
Blood, The Journal of the American Society of Hematology 133 (10), 1071-1085, 2019
1272019
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, ...
Nature communications 12 (1), 1334, 2021
1032021
Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma
AL Kennedy, M Vallurupalli, L Chen, B Crompton, G Cowley, F Vazquez, ...
Oncotarget 6 (30), 30178, 2015
882015
Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci
AL Kennedy, T McBryan, GH Enders, FB Johnson, R Zhang, PD Adams
Cell division 5, 1-11, 2010
722010
Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1
PC Scacheri, JS Crabtree, AL Kennedy, GP Swain, JM Ward, SJ Marx, ...
Mammalian Genome 15, 872-877, 2004
672004
Pediatric CNS-isolated hemophagocytic lymphohistiocytosis
LA Benson, H Li, LA Henderson, IH Solomon, A Soldatos, J Murphy, ...
Neurology: Neuroimmunology & Neuroinflammation 6 (3), e560, 2019
562019
Pediatric NUT-midline carcinoma: Therapeutic success employing a sarcoma based multimodal approach
S Storck, AL Kennedy, KJ Marcus, L Teot, J Vaughn, AK Gnekow, B Märkl, ...
Pediatric hematology and oncology 34 (4), 231-237, 2017
562017
Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy
AL Kennedy, PD Adams, JP Morton
Small GTPases 2 (5), 36-49, 2011
372011
Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability
PC Scacheri, AL Kennedy, K Chin, MT Miller, JG Hodgson, JW Gray, ...
Cancer research 64 (19), 7039-7044, 2004
282004
Dissecting ELANE neutropenia pathogenicity by human HSC gene editing
S Rao, Y Yao, JS de Brito, Q Yao, AH Shen, RE Watkinson, AL Kennedy, ...
Cell Stem Cell 28 (5), 833-845. e5, 2021
272021
Central nervous system–restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation
H Li, LA Benson, LA Henderson, IH Solomon, AL Kennedy, A Soldatos, ...
Blood Advances 3 (4), 503-507, 2019
132019
The frequent and clinically benign anomalies of chromosomes 7 and 20 in Shwachman-diamond syndrome may be subject to further clonal variations
AW Khan, A Kennedy, E Furutani, K Myers, A Frattini, F Acquati, P Roccia, ...
Molecular Cytogenetics 14, 1-9, 2021
102021
V804M RET mutation in MEN 2A: first report
PC Scacheri, JS Crabtree, AL Kennedy, GP Swain, JM Ward, SJ Marx, ...
JOURNAL OF INTERNAL MEDICINE 255 (6), 712-712, 2004
82004
Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma. Oncotarget. 2015; 6: 30178–93
AL Kennedy, M Vallurupalli, L Chen, B Crompton, G Cowley, F Vazquez, ...
PubMed Abstract| Publisher Full Text| Free Full Text, 0
7
Pediatric Acute Myeloid Leukemia with Nucleophosmin Mutations Is Characterized by a Gene Expression Signature with Dysregulated HOX Gene Expression Distinct from …
CG Mullighan, AL Kennedy, X Zhou, SA Shurtleff, JR Downing
Blood, The Journal of the American Society of Hematology 106 (11), 2993-2993, 2005
52005
Targeting EZH2 for the treatment of hepatosplenic T-cell lymphoma
Y Pikman, AS Conway, AL Robichaud, S Kitara, AJ Church, AL Kennedy, ...
Blood Advances 4 (7), 1265-1269, 2020
42020
Large genomic deletions in Shwachman-Diamond syndrome
LJ McReynolds, K Jones, K Teshome, A Kennedy, A Shimamura, N Giri, ...
Blood 132, 2586, 2018
22018
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