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Hayley E Bullen
Hayley E Bullen
Verified email at burnet.edu.au
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Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX)
HE Bullen, SC Charnaud, M Kalanon, DT Riglar, C Dekiwadia, ...
Journal of Biological Chemistry 287 (11), 7871-7884, 2012
1722012
Phosphatidic acid-mediated signaling regulates microneme secretion in Toxoplasma
HE Bullen, Y Jia, Y Yamaryo-Botté, H Bisio, O Zhang, NK Jemelin, ...
Cell host & microbe 19 (3), 349-360, 2016
1702016
A novel family of Apicomplexan glideosome-associated proteins with an inner membrane-anchoring role
HE Bullen, CJ Tonkin, RA O'Donnell, WH Tham, AT Papenfuss, S Gould, ...
Journal of Biological Chemistry 284 (37), 25353-25363, 2009
1502009
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate
NA Counihan, SA Chisholm, HE Bullen, A Srivastava, PR Sanders, ...
Elife 6, e23217, 2017
1082017
Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes
DT Riglar, KL Rogers, E Hanssen, L Turnbull, HE Bullen, SC Charnaud, ...
Nature communications 4 (1), 1415, 2013
1002013
Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX …
B Elsworth, PR Sanders, T Nebl, S Batinovic, M Kalanon, CQ Nie, ...
Cellular microbiology 18 (11), 1551-1569, 2016
812016
Optimization of 2-anilino 4-amino substituted quinazolines into potent antimalarial agents with oral in vivo activity
PR Gilson, C Tan, KE Jarman, KN Lowes, JM Curtis, W Nguyen, ...
Journal of medicinal chemistry 60 (3), 1171-1188, 2017
512017
Protein kinase A is essential for invasion of Plasmodium falciparum into human erythrocytes
ML Wilde, T Triglia, D Marapana, JK Thompson, AA Kouzmitchev, ...
MBio 10 (5), 10.1128/mbio. 01972-19, 2019
422019
The triumvirate of signaling molecules controlling Toxoplasma microneme exocytosis: Cyclic GMP, calcium, and phosphatidic acid
HE Bullen, H Bisio, D Soldati-Favre
PLoS pathogens 15 (5), e1007670, 2019
392019
Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export
SC Charnaud, R Kumarasingha, HE Bullen, BS Crabb, PR Gilson
PLoS One 13 (11), e0204785, 2018
372018
Spatial organization of protein export in malaria parasite blood stages
SC Charnaud, TK Jonsdottir, PR Sanders, HE Bullen, BK Dickerman, ...
Traffic 19 (8), 605-623, 2018
372018
A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa
HE Bullen, D Soldati‐Favre
FEBS letters 590 (15), 2469-2481, 2016
332016
Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii
LE Kemp, M Rusch, A Adibekian, HE Bullen, A Graindorge, C Freymond, ...
Journal of Biological Chemistry 288 (38), 27002-27018, 2013
262013
A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4
PR Gilson, R Kumarasingha, J Thompson, X Zhang, JS Penington, ...
Scientific Reports 9 (1), 10292, 2019
242019
A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell
M Gabriela, KM Matthews, C Boshoven, B Kouskousis, TK Jonsdottir, ...
PLoS Pathogens 18 (2), e1009977, 2022
192022
Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells
TK Jonsdottir, NA Counihan, JK Modak, B Kouskousis, PR Sanders, ...
Cellular Microbiology 23 (8), e13332, 2021
192021
Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit
DR Littler, HE Bullen, KL Harvey, T Beddoe, BS Crabb, J Rossjohn, ...
Journal of Biological Chemistry 291 (49), 25375-25386, 2016
182016
Recent insights into the export of PEXEL/HTS-motif containing proteins in Plasmodium parasites
HE Bullen, BS Crabb, PR Gilson
Current opinion in microbiology 15 (6), 699-704, 2012
162012
Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity
TD Ashton, A Ngo, P Favuzza, HE Bullen, MR Gancheva, O Romeo, ...
Bioorganic Chemistry 117, 105359, 2021
112021
The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture
HE Bullen, PR Sanders, MG Dans, TK Jonsdottir, DT Riglar, O Looker, ...
Molecular Microbiology 117 (5), 1245-1262, 2022
102022
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