| Heart disease and stroke statistics 2005 update American Heart Association http://www. americanheart. org/statistics/, 2005 | 8548* | 2005 |
| A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ... Cell 72 (6), 971-983, 1993 | 7323 | 1993 |
| Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis LA Farrer, LA Cupples, JL Haines, B Hyman, WA Kukull, R Mayeux, ... Jama 278 (16), 1349-1356, 1997 | 5331 | 1997 |
| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3512 | 2010 |
| Neuropathological classification of Huntington's disease JP Vonsattel, RH Myers, TJ Stevens, RJ Ferrante, ED Bird, ... Journal of Neuropathology & Experimental Neurology 44 (6), 559-577, 1985 | 3059 | 1985 |
| Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease MA Nalls, N Pankratz, CM Lill, CB Do, DG Hernandez, M Saad, ... Nature genetics 46 (9), 989-993, 2014 | 1991 | 2014 |
| Effectiveness of Covid-19 vaccines against the B. 1.617. 2 (Delta) variant JL Bernal, N Andrews, C Gower, E Gallagher, R Simmons, S Thelwall, ... The New England journal of medicine, 2021 | 1923 | 2021 |
| The genetic defect causing familial Alzheimer's disease maps on chromosome 21 PH St George-Hyslop, RE Tanzi, RJ Polinsky, JL Haines, L Nee, ... Science 235 (4791), 885-890, 1987 | 1628 | 1987 |
| Trinucleotide repeat length instability and age of onset in Huntington's disease MP Duyao, CM Ambrose, RH Myers, A Novelletto, F Persichetti, M Frontali, ... Nature genetics 4 (4), 387-392, 1993 | 1367 | 1993 |
| Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations F Soldner, J Laganière, AW Cheng, D Hockemeyer, Q Gao, R Alagappan, ... Cell 146 (2), 318-331, 2011 | 926 | 2011 |
| Familial lipoprotein disorders in patients with premature coronary artery disease. JJ Genest Jr, SS Martin-Munley, JR McNamara, JM Ordovas, J Jenner, ... Circulation 85 (6), 2025-2033, 1992 | 923 | 1992 |
| Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study CJ O’Donnell, K Lindpaintner, MG Larson, VS Rao, JM Ordovas, ... Circulation 97 (18), 1766-1772, 1998 | 753 | 1998 |
| CAG repeat number governs the development rate of pathology in Huntington's disease JB Penney Jr, JP Vonsattel, ME Macdonald, JF Gusella, RH Myers Annals of Neurology: Official Journal of the American Neurological …, 1997 | 740 | 1997 |
| Evidence for a gene influencing blood pressure on chromosome 17: genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study D Levy, AL DeStefano, MG Larson, CJ O’Donnell, RP Lifton, H Gavras, ... Hypertension 36 (4), 477-483, 2000 | 733 | 2000 |
| Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study JPG Vonsattel, RH Myers, E Tessa Hedley‐Whyte, AH Ropper, ED Bird, ... Annals of Neurology: Official Journal of the American Neurological …, 1991 | 656 | 1991 |
| Apolipoprotein E alleles, dyslipidemia, and coronary heart disease: the Framingham Offspring Study PWF Wilson, RH Myers, MG Larson, JM Ordovas, PA Wolf, EJ Schaefer Jama 272 (21), 1666-1671, 1994 | 642 | 1994 |
| Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database CM Lill, JT Roehr, MB McQueen, FK Kavvoura, S Bagade, BMM Schjeide, ... PLoS genetics 8 (3), e1002548, 2012 | 613 | 2012 |
| Genetic signatures of exceptional longevity in humans P Sebastiani, N Solovieff, AT DeWan, KM Walsh, A Puca, SW Hartley, ... PloS one 7 (1), e29848, 2012 | 584 | 2012 |
| Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression F Soldner, Y Stelzer, CS Shivalila, BJ Abraham, JC Latourelle, MI Barrasa, ... Nature 533 (7601), 95-99, 2016 | 540 | 2016 |
| Genomewide association study for susceptibility genes contributing to familial Parkinson disease N Pankratz, JB Wilk, JC Latourelle, AL DeStefano, C Halter, EW Pugh, ... Human genetics 124, 593-605, 2009 | 529 | 2009 |
