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Manuel Leonetti
Manuel Leonetti
Group Leader; Chan Zuckerberg Biohub
Verified email at czbiohub.org - Homepage
Title
Cited by
Cited by
Year
Reprogramming human T cell function and specificity with non-viral genome targeting
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
7502018
Pervasive functional translation of noncanonical human open reading frames
J Chen, AD Brunner, JZ Cogan, JK Nuñez, AP Fields, B Adamson, ...
Science 367 (6482), 1140-1146, 2020
4492020
Versatile protein tagging in cells with split fluorescent protein
D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ...
Nature communications 7 (1), 11046, 2016
4062016
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ...
Cell 184 (9), 2503-2519. e17, 2021
3562021
Structure of the human BK channel Ca2+-activation apparatus at 3.0 Å resolution
P Yuan, MD Leonetti, AR Pico, Y Hsiung, R MacKinnon
Science 329 (5988), 182-186, 2010
3502010
A scalable strategy for high-throughput GFP tagging of endogenous human proteins
MD Leonetti, S Sekine, D Kamiyama, JS Weissman, B Huang
Proceedings of the National Academy of Sciences 113 (25), E3501-E3508, 2016
2272016
Improved split fluorescent proteins for endogenous protein labeling
S Feng, S Sekine, V Pessino, H Li, MD Leonetti, B Huang
Nature communications 8 (1), 370, 2017
2252017
OpenCell: Endogenous tagging for the cartography of human cellular organization
NH Cho, KC Cheveralls, AD Brunner, K Kim, AC Michaelis, P Raghavan, ...
Science 375 (6585), eabi6983, 2022
1972022
Functional and structural analysis of the human SLO3 pH-and voltage-gated K+ channel
MD Leonetti, P Yuan, Y Hsiung, R MacKinnon
Proceedings of the National Academy of Sciences 109 (47), 19274-19279, 2012
1692012
Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel
P Yuan, MD Leonetti, Y Hsiung, R MacKinnon
Nature 481 (7379), 94-97, 2012
1612012
Ion selectivity in a semisynthetic K+ channel locked in the conductive conformation
FI Valiyaveetil, M Leonetti, TW Muir, R MacKinnon
Science 314 (5801), 1004-1007, 2006
1592006
Epi-illumination SPIM for volumetric imaging with high spatial-temporal resolution
B Yang, X Chen, Y Wang, S Feng, V Pessino, N Stuurman, NH Cho, ...
Nature methods 16 (6), 501-504, 2019
1372019
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics
D Mahdessian, AJ Cesnik, C Gnann, F Danielsson, L Stenström, M Arif, ...
Nature 590 (7847), 649-654, 2021
1232021
Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
JJ Chen, DL Nathaniel, P Raghavan, M Nelson, R Tian, E Tse, JY Hong, ...
Journal of Biological Chemistry 294 (50), 18952-18966, 2019
1132019
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
L Stenström, D Mahdessian, C Gnann, AJ Cesnik, W Ouyang, ...
Molecular systems biology 16 (8), e9469, 2020
1092020
Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells
RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ...
Nature biotechnology 37 (9), 1034-1037, 2019
1012019
Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors
L Mony, L Krzaczkowski, M Leonetti, A Le Goff, K Alarcon, J Neyton, ...
Molecular pharmacology 75 (1), 60-74, 2009
672009
Conserved functions of ether lipids and sphingolipids in the early secretory pathway
N Jiménez-Rojo, MD Leonetti, V Zoni, A Colom, S Feng, NR Iyengar, ...
Current Biology 30 (19), 3775-3787. e7, 2020
642020
Self-supervised deep learning encodes high-resolution features of protein subcellular localization
H Kobayashi, KC Cheveralls, MD Leonetti, LA Royer
Nature methods 19 (8), 995-1003, 2022
622022
Design and specificity of long ssDNA donors for CRISPR-based knock-in
H Li, KA Beckman, V Pessino, B Huang, JS Weissman, MD Leonetti
BioRxiv, 178905, 2017
602017
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