Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7 RJ Webster, KM Giles, KJ Price, PM Zhang, JS Mattick, PJ Leedman Journal of Biological Chemistry 284 (9), 5731-5741, 2009 | 557 | 2009 |
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA DI Yu, AHM Tan, X Hu, V Athanasopoulos, N Simpson, DG Silva, A Hutloff, ... Nature 450 (7167), 299-303, 2007 | 476 | 2007 |
MRNA stability and the control of gene expression: implications for human disease EM Hollams, KM Giles, AM Thomson, PJ Leedman Neurochemical research 27, 957-980, 2002 | 278 | 2002 |
miR-331-3p regulates ERBB-2 expression and androgen receptor signaling in prostate cancer MR Epis, KM Giles, A Barker, TS Kendrick, PJ Leedman Journal of Biological Chemistry 284 (37), 24696-24704, 2009 | 198 | 2009 |
Novel binding of HuR and poly (C)-binding protein to a conserved UC-rich motif within the 3′-untranslated region of the androgen receptor messenger RNA BB Yeap, DC Voon, JP Vivian, RK McCulloch, AM Thomson, KM Giles, ... Journal of Biological Chemistry 277 (30), 27183-27192, 2002 | 179 | 2002 |
Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib KM Giles, FC Kalinowski, PA Candy, MR Epis, PM Zhang, AD Redfern, ... Molecular cancer therapeutics 12 (11), 2541-2558, 2013 | 169 | 2013 |
miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion A Fowler, D Thomson, K Giles, S Maleki, E Mreich, H Wheeler, ... European journal of cancer 47 (6), 953-963, 2011 | 157 | 2011 |
SLIRP, a small SRA binding protein, is a nuclear receptor corepressor EC Hatchell, SM Colley, DJ Beveridge, MR Epis, LM Stuart, KM Giles, ... Molecular cell 22 (5), 657-668, 2006 | 152 | 2006 |
RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators AD Redfern, SM Colley, DJ Beveridge, N Ikeda, MR Epis, X Li, CE Foulds, ... Proceedings of the national academy of sciences 110 (16), 6536-6541, 2013 | 145 | 2013 |
microRNA-7: a tumor suppressor miRNA with therapeutic potential FC Kalinowski, RAM Brown, C Ganda, KM Giles, MR Epis, J Horsham, ... The international journal of biochemistry & cell biology 54, 312-317, 2014 | 140 | 2014 |
The 3′-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly (C)-binding protein KM Giles, JM Daly, DJ Beveridge, AM Thomson, DC Voon, HM Furneaux, ... Journal of Biological Chemistry 278 (5), 2937-2946, 2003 | 128 | 2003 |
Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors MF Gowen, KM Giles, D Simpson, J Tchack, H Zhou, U Moran, Z Dawood, ... Journal of translational medicine 16, 1-12, 2018 | 116 | 2018 |
The RNA-binding protein HuR opposes the repression of ERBB-2 gene expression by microRNA miR-331-3p in prostate cancer cells MR Epis, A Barker, KM Giles, DJ Beveridge, PJ Leedman Journal of Biological Chemistry 286 (48), 41442-41454, 2011 | 107 | 2011 |
miRNA-7-5p inhibits melanoma cell migration and invasion KM Giles, RAM Brown, MR Epis, FC Kalinowski, PJ Leedman Biochemical and biophysical research communications 430 (2), 706-710, 2013 | 101 | 2013 |
The evolution of MHC diversity by segmental duplication and transposition of retroelements JK Kulski, S Gaudieri, M Bellgard, L Balmer, K Giles, H Inoko, RL Dawkins Journal of Molecular Evolution 45, 599-609, 1997 | 92 | 1997 |
Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 FC Kalinowski, KM Giles, PA Candy, A Ali, C Ganda, MR Epis, ... PloS one 7 (10), e47067, 2012 | 89 | 2012 |
microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB KM Giles, RAM Brown, C Ganda, MJ Podgorny, PA Candy, LC Wintle, ... Oncotarget 7 (22), 31663, 2016 | 85 | 2016 |
Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes S Singer, R Zhao, AM Barsotti, A Ouwehand, M Fazollahi, E Coutavas, ... Molecular cell 48 (5), 799-810, 2012 | 74 | 2012 |
miR-331-3p regulates expression of neuropilin-2 in glioblastoma MR Epis, KM Giles, PA Candy, RJ Webster, PJ Leedman Journal of Neuro-oncology 116, 67-75, 2014 | 72 | 2014 |
Sequence requirements for RNA binding by HuR and AUF1 A Barker, MR Epis, CJ Porter, BR Hopkins, MCJ Wilce, JA Wilce, KM Giles, ... The journal of biochemistry 151 (4), 423-437, 2012 | 71 | 2012 |