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Nicholas Fraser
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Evolution of protein quaternary structure in response to selective pressure for increased thermostability
NJ Fraser, JW Liu, PD Mabbitt, GJ Correy, CW Coppin, M Lethier, ...
Journal of Molecular Biology 428 (11), 2359-2371, 2016
472016
Molecular basis for the behavioral effects of the odorant degrading enzyme Esterase 6 in Drosophila
F Younus, NJ Fraser, CW Coppin, JW Liu, GJ Correy, T Chertemps, ...
Scientific reports 7 (1), 46188, 2017
392017
Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron
E Sugrue, NJ Fraser, DH Hopkins, PD Carr, JL Khurana, JG Oakeshott, ...
Applied and environmental microbiology 81 (7), 2612-2624, 2015
302015
Conformational disorganization within the active site of a recently evolved organophosphate hydrolase limits its catalytic efficiency
PD Mabbitt, GJ Correy, T Meirelles, NJ Fraser, ML Coote, CJ Jackson
Biochemistry 55 (9), 1408-1417, 2016
232016
Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector Culex quinquefasciatus: What Makes an Enzyme a Good Insecticide Sponge?
DH Hopkins, NJ Fraser, PD Mabbitt, PD Carr, JG Oakeshott, CJ Jackson
Biochemistry 56 (41), 5512-5525, 2017
222017
The synthesis of certain derivatives and analogues of (−)-and (+)-galanthamine and an assessment of their capacities to inhibit acetylcholine esterase
JN Buckler, ES Taher, NJ Fraser, AC Willis, PD Carr, CJ Jackson, ...
The Journal of Organic Chemistry 82 (15), 7869-7886, 2017
182017
Total Syntheses of the 3H-Pyrrolo[2,3-c]quinolone-Containing Alkaloids Marinoquinolines A–F, K, and Aplidiopsamine A Using a Palladium-Catalyzed Ullmann …
B Bolte, CS Bryan, PP Sharp, S Sayyahi, C Rihouey, A Kendrick, P Lan, ...
The Journal of Organic Chemistry 85 (2), 650-663, 2019
162019
Mapping the accessible conformational landscape of an insect carboxylesterase using conformational ensemble analysis and kinetic crystallography
GJ Correy, PD Carr, T Meirelles, PD Mabbitt, NJ Fraser, M Weik, ...
Structure 24 (6), 977-987, 2016
142016
Deuterium effects on human serum albumin in solution
J White, V Laux, N Fraser, D Heß, M Haertlein, T Forsyth
Physica B: Condensed Matter 551, 208-211, 2018
22018
Structure and function studies of insect carboxylesterases
N Fraser
The Australian National University, 2017
12017
Laboratory-directed evolution as a tool for anticipating insecticide resistance
GJ Correy, P Mabbitt, N Fraser, C Jackson, JW Liu, J Oakeshott
2017
Research Publication Repository
NJ Fraser, JW Liu, PD Mabbitt, G Correy, CW Coppin, M Lethier, ...
2016
Elucidating the role of Esterase-6 from Drosophila melanogaster in the olfactory response
NJ Fraser, F Younus, JW Liu, C Coppin, G Pandey, JG Oakeshott, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 71, S229-S230, 2015
2015
HAL-BIOEMCO
F Younus, NJ Fraser, CW Coppin, JW Liu, GJ Correy
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Articles 1–14