| Strategies to address low drug solubility in discovery and development HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ... Pharmacological reviews 65 (1), 315-499, 2013 | 1657 | 2013 |
| Identification of an antimalarial synthetic trioxolane drug development candidate JL Vennerstrom, S Arbe-Barnes, R Brun, SA Charman, FCK Chiu, ... Nature 430 (7002), 900-904, 2004 | 776 | 2004 |
| Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ PA Adlard, RA Cherny, DI Finkelstein, E Gautier, E Robb, M Cortes, ... Neuron 59 (1), 43-55, 2008 | 773 | 2008 |
| Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound SA Charman, WN Charman, MC Rogge, TD Wilson, FJ Dutko, CW Pouton Pharmaceutical research 9, 87-93, 1992 | 627 | 1992 |
| Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria SA Charman, S Arbe-Barnes, IC Bathurst, R Brun, M Campbell, ... Proceedings of the National Academy of Sciences 108 (11), 4400-4405, 2011 | 443 | 2011 |
| A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 430 | 2015 |
| A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria MA Phillips, J Lotharius, K Marsh, J White, A Dayan, KL White, ... Science translational medicine 7 (296), 296ra111-296ra111, 2015 | 321 | 2015 |
| Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors … JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, ... Journal of medicinal chemistry 54 (15), 5540-5561, 2011 | 318 | 2011 |
| Lymphatic transport of proteins after subcutaneous administration CJH Porter, SA Charman Journal of pharmaceutical sciences 89 (3), 297-310, 2000 | 295 | 2000 |
| Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice R Gujjar, A Marwaha, F El Mazouni, J White, KL White, S Creason, ... Journal of medicinal chemistry 52 (7), 1864-1872, 2009 | 290 | 2009 |
| Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Y Yuthavong, B Tarnchompoo, T Vilaivan, P Chitnumsub, ... Proceedings of the National Academy of Sciences 109 (42), 16823-16828, 2012 | 274 | 2012 |
| (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 259 | 2014 |
| Subcutaneous drug delivery and the role of the lymphatics DN McLennan, CJH Porter, SA Charman Drug Discovery Today: Technologies 2 (1), 89-96, 2005 | 251 | 2005 |
| Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 245 | 2013 |
| Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase T Paquet, C Le Manach, DG Cabrera, Y Younis, PP Henrich, TS Abraham, ... Science translational medicine 9 (387), eaad9735, 2017 | 243 | 2017 |
| Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ... Nature 560 (7717), 253-257, 2018 | 208 | 2018 |
| Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis JS Doggett, A Nilsen, I Forquer, KW Wegmann, L Jones-Brando, ... Proceedings of the National Academy of Sciences 109 (39), 15936-15941, 2012 | 194 | 2012 |
| Lead Optimization of Aryl and Aralkyl Amine-Based Triazolopyrimidine Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial … R Gujjar, F El Mazouni, KL White, J White, S Creason, DM Shackleford, ... Journal of medicinal chemistry 54 (11), 3935-3949, 2011 | 185 | 2011 |
| Techniques for assessing the effects of pharmaceutical excipients on the aggregation of porcine growth hormone SA Charman, KL Mason, WN Charman Pharmaceutical research 10, 954-962, 1993 | 180 | 1993 |
| Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative … BL Flynn, GS Gill, DW Grobelny, JH Chaplin, D Paul, AF Leske, ... Journal of medicinal chemistry 54 (17), 6014-6027, 2011 | 164 | 2011 |
