| ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro H Stanton, FM Rogerson, CJ East, SB Golub, KE Lawlor, CT Meeker, ... Nature 434 (7033), 648-652, 2005 | 1024 | 2005 |
| RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL KE Lawlor, N Khan, A Mildenhall, M Gerlic, BA Croker, AA D’Cruz, C Hall, ... Nature communications 6, 6282, 2015 | 595 | 2015 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 587 | 2014 |
| Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation JE Vince, WWL Wong, I Gentle, KE Lawlor, R Allam, L O'reilly, K Mason, ... Immunity 36 (2), 215-227, 2012 | 521 | 2012 |
| Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ... Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017 | 387 | 2017 |
| FcγRIIb controls bone marrow plasma cell persistence and apoptosis Z Xiang, AJ Cutler, RJ Brownlie, K Fairfax, KE Lawlor, E Severinson, ... Nature immunology 8 (4), 419, 2007 | 374 | 2007 |
| TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice JA Rickard, H Anderton, N Etemadi, U Nachbur, M Darding, N Peltzer, ... Elife 3, e03464, 2014 | 255 | 2014 |
| Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair CB Little, CT Meeker, SB Golub, KE Lawlor, PJ Farmer, SM Smith, ... The Journal of clinical investigation 117 (6), 1627-1636, 2007 | 244 | 2007 |
| TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells KR Balka, C Louis, TL Saunders, AM Smith, DJ Calleja, DB D’Silva, ... Cell Reports 31 (1), 107492, 2020 | 242 | 2020 |
| Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non‐apoptotic caspase‐8 is required for inflammasome priming R Allam, KE Lawlor, ECW Yu, AL Mildenhall, DM Moujalled, RS Lewis, ... EMBO reports 15 (9), 982-990, 2014 | 240 | 2014 |
| Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, ... Nature 577 (7788), 103-108, 2020 | 224 | 2020 |
| Distinct cell-specific control of autoimmunity and infection by FcγRIIb RJ Brownlie, KE Lawlor, HA Niederer, AJ Cutler, Z Xiang, MR Clatworthy, ... Journal of Experimental Medicine 205 (4), 883-895, 2008 | 211 | 2008 |
| The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and-7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell Reports 25 (9), 2339-2353. e4, 2018 | 185 | 2018 |
| TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 DM Moujalled, WD Cook, T Okamoto, J Murphy, KE Lawlor, JE Vince, ... Cell death & disease 4 (1), e465, 2014 | 174 | 2014 |
| Severe inflammatory arthritis and lymphadenopathy in the absence of TNF IK Campbell, K O’Donnell, KE Lawlor, IP Wicks The Journal of clinical investigation 107 (12), 1519-1527, 2001 | 173 | 2001 |
| cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner WWL Wong, JE Vince, N Lalaoui, KE Lawlor, D Chau, A Bankovacki, ... Blood 123 (16), 2562-2572, 2014 | 171 | 2014 |
| Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation PJ Egan, KE Lawlor, WS Alexander, IP Wicks The Journal of clinical investigation 111 (6), 915-924, 2003 | 157 | 2003 |
| IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome AJ Murphy, MJ Kraakman, HL Kammoun, D Dragoljevic, MKS Lee, ... Cell metabolism 23 (1), 155-164, 2016 | 156 | 2016 |
| Critical role for granulocyte colony-stimulating factor in inflammatory arthritis KE Lawlor, IK Campbell, D Metcalf, K O'Donnell, A van Nieuwenhuijze, ... Proceedings of the National Academy of Sciences 101 (31), 11398-11403, 2004 | 149 | 2004 |
| Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria? KE Lawlor, JE Vince Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (4), 1433-1440, 2014 | 142 | 2014 |
