Julien Sage
Julien Sage
Professor of Pediatrics and Genetics, Stanford University
Verified email at - Homepage
Cited by
Cited by
Comprehensive genomic profiles of small cell lung cancer
J George, JS Lim, SJ Jang, Y Cun, L Ozretić, G Kong, F Leenders, X Lu, ...
Nature 524 (7563), 47-53, 2015
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
M Peifer, L Fernández-Cuesta, ML Sos, J George, D Seidel, LH Kasper, ...
Nature genetics 44 (10), 1104-1110, 2012
Cellular mechanisms of tumour suppression by the retinoblastoma gene
DL Burkhart, J Sage
Nature Reviews Cancer 8 (9), 671-682, 2008
Discovery and preclinical validation of drug indications using compendia of public gene expression data
M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ...
Science translational medicine 3 (96), 96ra77-96ra77, 2011
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ...
Nature Reviews Cancer 19 (5), 289-297, 2019
Small-cell lung cancer
CM Rudin, E Brambilla, C Faivre-Finn, J Sage
Nature Reviews Disease Primers 7 (1), 3, 2021
Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization
J Sage, GJ Mulligan, LD Attardi, A Miller, SQ Chen, B Williams, ...
Genes & development 14 (23), 3037-3050, 2000
Targeting DNA damage response promotes antitumor immunity through STING-mediated T-cell activation in small cell lung cancer
T Sen, BL Rodriguez, L Chen, CMD Corte, N Morikawa, J Fujimoto, ...
Cancer discovery 9 (5), 646-661, 2019
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
J Sage, AL Miller, PA Pérez-Mancera, JM Wysocki, T Jacks
Nature 424 (6945), 223-228, 2003
From fly wings to targeted cancer therapies: a centennial for notch signaling
P Ntziachristos, JS Lim, J Sage, I Aifantis
Cancer cell 25 (3), 318-334, 2014
Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis
EE Gardner, BH Lok, VE Schneeberger, P Desmeules, LA Miles, ...
Cancer cell 31 (2), 286-299, 2017
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ...
The Journal of clinical investigation 126 (7), 2610-2620, 2016
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
PK Mazur, N Reynoird, P Khatri, PWTC Jansen, AW Wilkinson, S Liu, ...
Nature 510 (7504), 283-287, 2014
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
JS Lim, A Ibaseta, MM Fischer, B Cancilla, G O’Young, S Cristea, VC Luca, ...
Nature 545 (7654), 360-364, 2017
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ...
Cancer discovery 3 (12), 1364-1377, 2013
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ...
Nature medicine 21 (10), 1163-1171, 2015
pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4a tumor suppressor gene
Y Kotake, R Cao, P Viatour, J Sage, Y Zhang, Y Xiong
Genes & development 21 (1), 49-54, 2007
Nfib promotes metastasis through a widespread increase in chromatin accessibility
SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ...
Cell 166 (2), 328-342, 2016
PDGF signalling controls age-dependent proliferation in pancreatic β-cells
H Chen, X Gu, Y Liu, J Wang, SE Wirt, R Bottino, H Schorle, J Sage, ...
Nature 478 (7369), 349-355, 2011
A crucial requirement for Hedgehog signaling in small cell lung cancer
KS Park, LG Martelotto, M Peifer, ML Sos, AN Karnezis, MR Mahjoub, ...
Nature medicine 17 (11), 1504-1508, 2011
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