Finding the missing heritability of complex diseases TA Manolio, FS Collins, NJ Cox, DB Goldstein, LA Hindorff, DJ Hunter, ... Nature 461 (7265), 747-753, 2009 | 9999 | 2009 |
Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-18, 2007 | 2271 | 2007 |
Missing heritability and strategies for finding the underlying causes of complex disease EE Eichler, J Flint, G Gibson, A Kong, SM Leal, JH Moore, JH Nadeau Nature reviews genetics 11 (6), 446-450, 2010 | 2083 | 2010 |
Rare and common variants: twenty arguments G Gibson Nature Reviews Genetics 13 (2), 135-145, 2012 | 1489 | 2012 |
Assessing gene significance from cDNA microarray expression data via mixed models RD Wolfinger, G Gibson, ED Wolfinger, L Bennett, H Hamadeh, P Bushel, ... Journal of computational biology 8 (6), 625-637, 2001 | 1384 | 2001 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1068 | 2021 |
Perspective: evolution and detection of genetic robustness JAGM De Visser, J Hermisson, GP Wagner, LA Meyers, ... Evolution 57 (9), 1959-1972, 2003 | 828 | 2003 |
Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus SA Jenks, KS Cashman, E Zumaquero, UM Marigorta, AV Patel, X Wang, ... Immunity 49 (4), 725-739. e6, 2018 | 807 | 2018 |
The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster W Jin, RM Riley, RD Wolfinger, KP White, G Passador-Gurgel, G Gibson Nature genetics 29 (4), 389-395, 2001 | 766 | 2001 |
Uncovering cryptic genetic variation G Gibson, I Dworkin Nature Reviews Genetics 5 (9), 681-690, 2004 | 630 | 2004 |
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, ... The Lancet 389 (10080), 1710-1718, 2017 | 607 | 2017 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 513 | 2018 |
Canalization in evolutionary genetics: a stabilizing theory? G Gibson, G Wagner BioEssays 22 (4), 372-380, 2000 | 470 | 2000 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 464 | 2010 |
Hints of hidden heritability in GWAS G Gibson Nature genetics 42 (7), 558-560, 2010 | 402 | 2010 |
Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders S Ligthart, A Vaez, U Vősa, MG Stathopoulou, PS De Vries, BP Prins, ... The American Journal of Human Genetics 103 (5), 691-706, 2018 | 396 | 2018 |
Decanalization and the origin of complex disease G Gibson Nature Reviews Genetics 10 (2), 134-140, 2009 | 359 | 2009 |
Signatures of negative selection in the genetic architecture of human complex traits J Zeng, R De Vlaming, Y Wu, MR Robinson, LR Lloyd-Jones, L Yengo, ... Nature genetics 50 (5), 746-753, 2018 | 355 | 2018 |
Genes regulated by mating, sperm, or seminal proteins in mated female Drosophila melanogaster LA McGraw, G Gibson, AG Clark, MF Wolfner Current Biology 14 (16), 1509-1514, 2004 | 354 | 2004 |
The quantitative genetics of transcription G Gibson, B Weir TRENDS in Genetics 21 (11), 616-623, 2005 | 350 | 2005 |