| Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells JW Astin, J Batson, S Kadir, J Charlet, RA Persad, D Gillatt, JD Oxley, ... Nature cell biology 12 (12), 1194-1204, 2010 | 264 | 2010 |
| Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production CJ Hall, RH Boyle, JW Astin, MV Flores, SH Oehlers, LE Sanderson, ... Cell metabolism 18 (2), 265-278, 2013 | 236 | 2013 |
| Lymphatic vessels arise from specialized angioblasts within a venous niche J Nicenboim, G Malkinson, T Lupo, L Asaf, Y Sela, O Mayseless, ... Nature 522 (7554), 56-61, 2015 | 220 | 2015 |
| lyve1 expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafish KS Okuda, JW Astin, JP Misa, MV Flores, KE Crosier, PS Crosier Development 139 (13), 2381-2391, 2012 | 202 | 2012 |
| Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding ML Bochenek, S Dickinson, JW Astin, RH Adams, CD Nobes Journal of cell science 123 (8), 1235-1246, 2010 | 115 | 2010 |
| Pkd1 regulates lymphatic vascular morphogenesis during development B Coxam, A Sabine, NI Bower, KA Smith, C Pichol-Thievend, R Skoczylas, ... Cell reports 7 (3), 623-633, 2014 | 97 | 2014 |
| Vegfd can compensate for loss of Vegfc in zebrafish facial lymphatic sprouting JW Astin, MJL Haggerty, KS Okuda, L Le Guen, JP Misa, A Tromp, ... Development 141 (13), 2680-2690, 2014 | 80 | 2014 |
| Microtubule remodelling is required for the front–rear polarity switch during contact inhibition of locomotion S Kadir, JW Astin, L Tahtamouni, P Martin, CD Nobes Journal of cell science 124 (15), 2642-2653, 2011 | 78 | 2011 |
| Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli, and effects of paxilline intermediates on … LK McMillan, RL Carr, CA Young, JW Astin, RGT Lowe, EJ Parker, ... Molecular genetics and genomics 270, 9-23, 2003 | 75 | 2003 |
| Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1 JW Astin, NJ O’Neil, PE Kuwabara DNA repair 7 (2), 267-280, 2008 | 65 | 2008 |
| mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish K Koltowska, S Paterson, NI Bower, GJ Baillie, AK Lagendijk, JW Astin, ... Genes & development 29 (15), 1618-1630, 2015 | 62 | 2015 |
| Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model DD Britto, B Wyroba, W Chen, RA Lockwood, KB Tran, PR Shepherd, ... Disease models & mechanisms 11 (12), dmm035998, 2018 | 59 | 2018 |
| Zebrafish facial lymphatics develop through sequential addition of venous and non‐venous progenitors TCY Eng, W Chen, KS Okuda, JP Misa, Y Padberg, KE Crosier, ... EMBO reports 20 (5), e47079, 2019 | 54 | 2019 |
| Blocking fatty acid–fueled mROS production within macrophages alleviates acute gouty inflammation CJ Hall, LE Sanderson, LM Lawrence, B Pool, M Van Der Kroef, ... The Journal of clinical investigation 128 (5), 1752-1771, 2018 | 54 | 2018 |
| Anticancer organorhodium and-iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic activity S Parveen, M Hanif, E Leung, KKH Tong, A Yang, J Astin, GH De Zoysa, ... Chemical communications 55 (80), 12016-12019, 2019 | 47 | 2019 |
| An inducible transgene reports activation of macrophages in live zebrafish larvae LE Sanderson, AT Chien, JW Astin, KE Crosier, PS Crosier, CJ Hall Developmental & Comparative Immunology 53 (1), 63-69, 2015 | 47 | 2015 |
| An In Vivo Antilymphatic Screen in Zebrafish Identifies Novel Inhibitors of Mammalian Lymphangiogenesis and Lymphatic-Mediated Metastasis JW Astin, SMF Jamieson, TCY Eng, MV Flores, JP Misa, A Chien, ... Molecular cancer therapeutics 13 (10), 2450-2462, 2014 | 45 | 2014 |
| Regulation of contact inhibition of locomotion by Eph–ephrin signalling J Batson, JW Astin, CD Nobes Journal of microscopy 251 (3), 232-241, 2013 | 42 | 2013 |
| DMXAA (Vadimezan, ASA404) is a multi-kinase inhibitor targeting VEGFR2 in particular CM Buchanan, JH Shih, JW Astin, GW Rewcastle, JU Flanagan, ... Clinical Science 122 (10), 449-465, 2012 | 41 | 2012 |
| Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli B Scott, CA Young, S Saikia, LK McMillan, BJ Monahan, A Koulman, ... Toxins 5 (8), 1422-1446, 2013 | 39 | 2013 |
