| Structure of a mammalian ryanodine receptor R Zalk, OB Clarke, A des Georges, RA Grassucci, S Reiken, F Mancia, ... Nature 517 (7532), 44-49, 2015 | 488 | 2015 |
| Structural basis for gating and activation of RyR1 A des Georges, OB Clarke, R Zalk, Q Yuan, KJ Condon, RA Grassucci, ... Cell 167 (1), 145-157. e17, 2016 | 394 | 2016 |
| Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex AH Nguyen, ARB Thomsen, TJ Cahill, R Huang, LY Huang, T Marcink, ... Nature structural & molecular biology 26 (12), 1123-1131, 2019 | 192 | 2019 |
| Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain MD Boersma, HS Haase, KJ Peterson-Kaufman, EF Lee, OB Clarke, ... Journal of the American Chemical Society 134 (1), 315-323, 2012 | 172 | 2012 |
| Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels OB Clarke, AT Caputo, AP Hill, JI Vandenberg, BJ Smith, JM Gulbis Cell 141 (6), 1018-1029, 2010 | 169 | 2010 |
| Structure of the STRA6 receptor for retinol uptake Y Chen, OB Clarke, J Kim, S Stowe, YK Kim, Z Assur, M Cavalier, ... Science 353 (6302), aad8266, 2016 | 160 | 2016 |
| Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation VI Petrou, CM Herrera, KM Schultz, OB Clarke, J Vendome, D Tomasek, ... Science 351 (6273), 608-612, 2016 | 118 | 2016 |
| Metal binding affinities of Arabidopsis zinc and copper transporters: Selectivities match the relative, but not the absolute, affinities of their amino-terminal domains M Zimmermann, O Clarke, JM Gulbis, DW Keizer, RS Jarvis, CS Cobbett, ... Biochemistry 48 (49), 11640-11654, 2009 | 95 | 2009 |
| Structural basis of omega-3 fatty acid transport across the blood–brain barrier RJ Cater, GL Chua, SK Erramilli, JE Keener, BC Choy, P Tokarz, CF Chin, ... Nature 595 (7866), 315-319, 2021 | 91 | 2021 |
| Structure of human GABAB receptor in an inactive state J Park, Z Fu, A Frangaj, J Liu, L Mosyak, T Shen, VN Slavkovich, KM Ray, ... Nature 584 (7820), 304-309, 2020 | 78 | 2020 |
| Discovery and molecular characterization of a Bcl-2–regulated cell death pathway in schistosomes EF Lee, OB Clarke, M Evangelista, Z Feng, TP Speed, EB Tchoubrieva, ... Proceedings of the National Academy of Sciences 108 (17), 6999-7003, 2011 | 68 | 2011 |
| Structural basis of WLS/Evi-mediated Wnt transport and secretion R Nygaard, J Yu, J Kim, DR Ross, G Parisi, OB Clarke, DM Virshup, ... Cell 184 (1), 194-206. e14, 2021 | 63 | 2021 |
| Gating movements and ion permeation in HCN4 pacemaker channels A Saponaro, D Bauer, MH Giese, P Swuec, A Porro, F Gasparri, ... Molecular Cell 81 (14), 2929-2943. e6, 2021 | 62 | 2021 |
| Architecture of the human erythrocyte ankyrin-1 complex F Vallese, K Kim, LY Yen, JD Johnston, AJ Noble, T Calì, OB Clarke Nature Structural & Molecular Biology 29 (7), 706-718, 2022 | 56 | 2022 |
| Insights into Duffy binding-like domains through the crystal structure and function of the merozoite surface protein MSPDBL2 from Plasmodium falciparum AN Hodder, PE Czabotar, AD Uboldi, OB Clarke, CS Lin, J Healer, ... Journal of Biological Chemistry 287 (39), 32922-32939, 2012 | 54 | 2012 |
| Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop A Papa, J Kushner, JA Hennessey, AN Katchman, SI Zakharov, B Chen, ... Circulation research 128 (1), 76-88, 2021 | 52 | 2021 |
| Structural basis for phosphatidylinositol-phosphate biosynthesis OB Clarke, D Tomasek, CD Jorge, MB Dufrisne, M Kim, S Banerjee, ... Nature communications 6 (1), 1-11, 2015 | 52 | 2015 |
| Structural basis for catalysis in a CDP-alcohol phosphotransferase G Sciara, OB Clarke, D Tomasek, B Kloss, S Tabuso, R Byfield, R Cohn, ... Nature communications 5 (1), 1-10, 2014 | 50 | 2014 |
| Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1 W Wong, CT Skau, DS Marapana, E Hanssen, NL Taylor, DT Riglar, ... Proceedings of the National Academy of Sciences 108 (24), 9869-9874, 2011 | 48 | 2011 |
| Intracellular calcium leak as a therapeutic target for RYR1-related myopathies A Kushnir, JJ Todd, JW Witherspoon, Q Yuan, S Reiken, H Lin, RH Munce, ... Acta neuropathologica 139 (6), 1089-1104, 2020 | 47 | 2020 |
Andrew R. MarksColumbia UniversityVerified email at columbia.edu
