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Xu Wang
Xu Wang
Principal Scientist, Chemistry at Arbutus Biopharma, Inc.
Verified email at arbutusbio.com
Title
Cited by
Cited by
Year
Benzenediol-berberine hybrids: Multifunctional agents for Alzheimer’s disease
H Jiang, X Wang, L Huang, Z Luo, T Su, K Ding, X Li
Bioorganic & medicinal chemistry 19 (23), 7228-7235, 2011
1012011
The methylerythritol phosphate pathway: promising drug targets in the fight against tuberculosis
X Wang, CS Dowd
ACS infectious diseases 4 (3), 278-290, 2018
532018
MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis
RL Edwards, RC Brothers, X Wang, MI Maron, PD Ziniel, PS Tsang, ...
Scientific reports 7 (1), 8400, 2017
332017
Structure–activity relationships of the MEPicides: N-acyl and O-linked analogs of FR900098 as inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis
G San Jose, ER Jackson, A Haymond, C Johny, RL Edwards, X Wang, ...
ACS infectious diseases 2 (12), 923-935, 2016
312016
MEPicides: α, β-unsaturated fosmidomycin analogues as DXR inhibitors against malaria
X Wang, RL Edwards, H Ball, C Johnson, A Haymond, M Girma, ...
Journal of medicinal chemistry 61 (19), 8847-8858, 2018
282018
Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD+) synthetase inhibitors as potential antitubercular agents
X Wang, YM Ahn, AG Lentscher, JS Lister, RC Brothers, MM Kneen, ...
Bioorganic & medicinal chemistry letters 27 (18), 4426-4430, 2017
252017
Potent, specific MEPicides for treatment of zoonotic staphylococci
RL Edwards, I Heueck, SG Lee, IT Shah, JJ Miller, AJ Jezewski, MO Mikati, ...
PLoS pathogens 16 (6), e1007806, 2020
142020
Mechanism of Action of N-Acyl and N-Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of …
MB Girma, HS Ball, X Wang, RC Brothers, ER Jackson, MJ Meyers, ...
ACS omega 6 (42), 27630-27639, 2021
42021
MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase
X Wang, RL Edwards, HS Ball, KM Heidel, RC Brothers, C Johnson, ...
ACS Infectious Diseases 9 (7), 1387-1395, 2023
12023
Antibiotics for veterinary staphylococcal infections
D Cynthia, AO John, R Edwards, KM Heidel, X Wang, R Chofor
US Patent App. 17/253,841, 2021
2021
Alkenyl and beta-substituted phosphonates as antimicrobial agents
D Cynthia, X Wang, RC Brothers, ARO John, R Edwards, M Meyers, ...
US Patent 11,098,072, 2021
2021
Chapter 17: Advances in the Development of Deubiquitinase (DUB) Inhibitors
Jian Wu, Xu Wang, Kumar Suresh
2019 Medicinal Chemistry Reviews 54, 357-377, 2019
2019
Evaluating fosmidomycin analogs as antimicrobial agents through 1-Deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibition
X Wang, R Edwards, A Haymond, R Brothers, H Boshoff, R Couch, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017
2017
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