WW domains of Nedd4 bind to the proline‐rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. O Staub, S Dho, P Henry, J Correa, T Ishikawa, J McGlade, D Rotin The EMBO journal 15 (10), 2371-2380, 1996 | 1043 | 1996 |
Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination O Staub, I Gautschi, T Ishikawa, K Breitschopf, A Ciechanover, L Schild, ... The EMBO journal, 1997 | 873 | 1997 |
Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression C Debonneville, SY Flores, E Kamynina, PJ Plant, C Tauxe, MA Thomas, ... The EMBO journal, 2001 | 825 | 2001 |
Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases D Rotin, O Staub, R Haguenauer-Tsapis The Journal of membrane biology 176, 1-17, 2000 | 485 | 2000 |
Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome H Abriel, J Loffing, JF Rebhun, JH Pratt, L Schild, JD Horisberger, D Rotin, ... The Journal of clinical investigation 103 (5), 667-673, 1999 | 450 | 1999 |
A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel E KAMYNINA, C DEBONNEVILLE, M Bens, A VANDEWALLE, O STAUB The FASEB Journal 15 (1), 204-214, 2001 | 354 | 2001 |
Functional expression of the epithelial Ca2+ channels (TRPV5 and TRPV6) requires association of the S100A10–annexin 2 complex SFJ van de Graaf, JGJ Hoenderop, D Gkika, D Lamers, J Prenen, ... The EMBO journal, 2003 | 337 | 2003 |
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination O Staub, H Abriel, P Plant, T Ishikawa, V Kanelis, R Saleki, ... Kidney international 57 (3), 809-815, 2000 | 279 | 2000 |
Role of ubiquitylation in cellular membrane transport O Staub, D Rotin Physiological reviews 86 (2), 669-707, 2006 | 271 | 2006 |
Cardiac Voltage-Gated Sodium Channel Nav1.5 Is Regulated by Nedd4-2 Mediated Ubiquitination MX van Bemmelen, JS Rougier, B Gavillet, F Apothéloz, D Daidié, ... Circulation research 95 (3), 284-291, 2004 | 253 | 2004 |
Concerted action of ENaC, Nedd4–2, and Sgk1 in transepithelial Na+ transport E Kamynina, O Staub American Journal of Physiology-Renal Physiology 283 (3), F377-F387, 2002 | 253 | 2002 |
The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization PJ Plant, H Yeger, O Staub, P Howard, D Rotin Journal of Biological Chemistry 272 (51), 32329-32336, 1997 | 253 | 1997 |
Serum-and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with … V Bhalla, D Daidie, H Li, AC Pao, LP LaGrange, J Wang, A Vandewalle, ... Molecular endocrinology 19 (12), 3073-3084, 2005 | 205 | 2005 |
Nedd4-2 modulates renal Na+-Cl− cotransporter via the aldosterone-SGK1-Nedd4-2 pathway JP Arroyo, D Lagnaz, C Ronzaud, N Vazquez, BS Ko, L Moddes, ... Journal of the American Society of Nephrology 22 (9), 1707-1719, 2011 | 182 | 2011 |
Early aldosterone-induced gene product regulates the epithelial sodium channel by deubiquitylation P Fakitsas, G Adam, MX van Bemmelen, F Fouladkou, A Patrignani, ... Journal of the American Society of Nephrology 18 (4), 1084-1092, 2007 | 179 | 2007 |
Sgk kinases and their role in epithelial transport J Loffing, SY Flores, O Staub Annu. Rev. Physiol. 68, 461-490, 2006 | 178 | 2006 |
Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2 PP Shi, XR Cao, EM Sweezer, TS Kinney, NR Williams, RF Husted, ... American Journal of Physiology-Renal Physiology 295 (2), F462-F470, 2008 | 174 | 2008 |
Nedd4. 1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding V Blot, F Perugi, B Gay, MC Prévost, L Briant, F Tangy, H Abriel, O Staub, ... Journal of cell science 117 (11), 2357-2367, 2004 | 174 | 2004 |
Aldosterone paradox: differential regulation of ion transport in distal nephron JP Arroyo, C Ronzaud, D Lagnaz, O Staub, G Gamba Physiology 26 (2), 115-123, 2011 | 168 | 2011 |
Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins JS Rougier, MX van Bemmelen, MC Bruce, T Jespersen, B Gavillet, ... American Journal of Physiology-Cell Physiology 288 (3), C692-C701, 2005 | 164 | 2005 |