AMPK directly activates mTORC2 to promote cell survival during acute energetic stress D Kazyken, B Magnuson, C Bodur, HA Acosta-Jaquez, D Zhang, X Tong, ... Science signaling 12 (585), eaav3249, 2019 | 197 | 2019 |
Hepatoprotective role of Sestrin2 against chronic ER stress HW Park, H Park, SH Ro, I Jang, IA Semple, DN Kim, M Kim, M Nam, ... Nature communications 5 (1), 4233, 2014 | 183 | 2014 |
Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis B Wang, G Huang, D Wang, A Li, Z Xu, R Dong, D Zhang, W Zhou Journal of hepatology 53 (3), 508-518, 2010 | 129 | 2010 |
Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling D Zhang, X Tong, B Arthurs, A Guha, L Rui, A Kamath, K Inoki, L Yin Journal of Biological Chemistry 289 (37), 25925-25935, 2014 | 104 | 2014 |
Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity D Zhang, X Tong, K VanDommelen, N Gupta, K Stamper, GF Brady, ... The Journal of clinical investigation 127 (7), 2855-2867, 2017 | 100 | 2017 |
MicroRNA-212 displays tumor-promoting properties in non-small cell lung cancer cells and targets the hedgehog pathway receptor PTCH1 Y Li, D Zhang, C Chen, Z Ruan, Y Li, Y Huang Molecular biology of the cell 23 (8), 1423-1434, 2012 | 97 | 2012 |
The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARα pathway D Zhang, X Tong, BB Nelson, E Jin, J Sit, N Charney, M Yang, MB Omary, ... Hepatology 68 (3), 883-896, 2018 | 80 | 2018 |
Cx31. 1 acts as a tumour suppressor in non‐small cell lung cancer (NSCLC) cell lines through inhibition of cell proliferation and metastasis D Zhang, C Chen, Y Li, X Fu, Y Xie, Y Li, Y Huang Journal of cellular and molecular medicine 16 (5), 1047-1059, 2012 | 78 | 2012 |
A meta-analysis of DNA repair gene XPC polymorphisms and cancer risk D Zhang, C Chen, X Fu, S Gu, Y Mao, Y Xie, Y Huang, Y Li Journal of human genetics 53 (1), 18-33, 2008 | 73 | 2008 |
Palmitate inhibits SIRT1-dependent BMAL1/CLOCK interaction and disrupts circadian gene oscillations in hepatocytes X Tong, D Zhang, B Arthurs, P Li, L Durudogan, N Gupta, L Yin PloS one 10 (6), e0130047, 2015 | 51 | 2015 |
Loss of hepatic CEACAM1: a unifying mechanism linking insulin resistance to obesity and non-alcoholic fatty liver disease G Heinrich, HE Ghadieh, SS Ghanem, HT Muturi, K Rezaei, QY Al-Share, ... Frontiers in endocrinology 8, 8, 2017 | 43 | 2017 |
TP53 Arg72Pro polymorphism and lung cancer risk: A meta‐analysis L Yan, D Zhang, C Chen, Y Mao, Y Xie, Y Li, Y Huang, B Han International journal of cancer 125 (12), 2903-2911, 2009 | 43 | 2009 |
Recruitment of histone methyltransferase G9a mediates transcriptional repression of Fgf21 gene by E4BP4 protein X Tong, D Zhang, K Buelow, A Guha, B Arthurs, HJM Brady, L Yin Journal of Biological Chemistry 288 (8), 5417-5425, 2013 | 41 | 2013 |
Deficiency of the mitochondrial NAD kinase causes stress-induced hepatic steatosis in mice K Zhang, H Kim, Z Fu, Y Qiu, Z Yang, J Wang, D Zhang, X Tong, L Yin, J Li, ... Gastroenterology 154 (1), 224-237, 2018 | 40 | 2018 |
Meta-analysis of three polymorphisms in the steroid-5-alpha-reductase, alpha polypeptide 2 gene (SRD5A2) and risk of prostate cancer X Li, Y Huang, X Fu, C Chen, D Zhang, L Yan, Y Xie, Y Mao, Y Li Mutagenesis 26 (3), 371-383, 2010 | 39 | 2010 |
E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis [S] X Tong, P Li, D Zhang, K VanDommelen, N Gupta, L Rui, MB Omary, ... Journal of lipid research 57 (7), 1219-1230, 2016 | 29 | 2016 |
Reduced hepatic carcinoembryonic antigen-related cell adhesion molecule 1 level in obesity G Heinrich, HT Muturi, K Rezaei, QY Al-Share, AM DeAngelis, ... Frontiers in endocrinology 8, 54, 2017 | 27 | 2017 |
DDB1-mediated CRY1 degradation promotes FOXO1-driven gluconeogenesis in liver X Tong, D Zhang, N Charney, E Jin, K VanDommelen, K Stamper, ... Diabetes 66 (10), 2571-2582, 2017 | 23 | 2017 |
The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis CJ Krebs, D Zhang, L Yin, DM Robins Molecular and cellular biology 34 (2), 221-232, 2014 | 22 | 2014 |
CUL4-DDB1-CDT2 E3 ligase regulates the molecular clock activity by promoting ubiquitination-dependent degradation of the mammalian CRY1 X Tong, D Zhang, A Guha, B Arthurs, V Cazares, N Gupta, L Yin PloS one 10 (10), e0139725, 2015 | 21 | 2015 |