Jonathan DF Wadsworth
Jonathan DF Wadsworth
Reader in Prion Diseases, UCL Faculty of Brain Sciences
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay
JDF Wadsworth, S Joiner, AF Hill, TA Campbell, M Desbruslais, ...
The Lancet 358 (9277), 171-180, 2001
7852001
Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report
SJ Wroe, S Pal, D Siddique, H Hyare, R Macfarlane, S Joiner, JM Linehan, ...
The Lancet 368 (9552), 2061-2067, 2006
4452006
BSE prions propagate as either variant CJD‐like or sporadic CJD‐like prion strains in transgenic mice expressing human prion protein
EA Asante, JM Linehan, M Desbruslais, S Joiner, I Gowland, AL Wood, ...
The EMBO Journal 21 (23), 6358-6366, 2002
3992002
Strain-specific prion-protein conformation determined by metal ions
JDF Wadsworth, AF Hill, S Joiner, GS Jackson, AR Clarke, J Collinge
Nature Cell Biology 1 (1), 55-59, 1999
3521999
Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
Z Jaunmuktane, S Mead, M Ellis, JDF Wadsworth, AJ Nicoll, J Kenny, ...
Nature 525 (7568), 247-250, 2015
3452015
Molecular classification of sporadic Creutzfeldt–Jakob disease
AF Hill, S Joiner, JDF Wadsworth, KCL Sidle, JE Bell, H Budka, ...
Brain 126 (6), 1333-1346, 2003
3412003
Human prion protein with valine 129 prevents expression of variant CJD phenotype
JDF Wadsworth, EA Asante, M Desbruslais, JM Linehan, S Joiner, ...
Science 306 (5702), 1793-1796, 2004
2712004
Molecular and clinical classification of human prion disease
JDF Wadsworth, AF Hill, JA Beck, J Collinge
British medical bulletin 66 (1), 241-254, 2003
1682003
Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis
M Kristiansen, MJ Messenger, PC Klöhn, S Brandner, JDF Wadsworth, ...
Journal of Biological Chemistry 280 (46), 38851-38861, 2005
1572005
Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
S Cronier, N Gros, MH Tattum, GS Jackson, AR Clarke, J Collinge, ...
Biochemical Journal 416 (2), 297-305, 2008
1422008
Neurotransmitter release is blocked intracellularly by botulinum neurotoxin, and this requires uptake of both toxin polypeptides by a process mediated by the larger chain
B Poulain, L Tauc, EA Maisey, JD Wadsworth, PM Mohan, JO Dolly
Proceedings of the National Academy of Sciences 85 (11), 4090-4094, 1988
1291988
Update on human prion disease
JDF Wadsworth, J Collinge
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (6), 598-609, 2007
1282007
A naturally occurring variant of the human prion protein completely prevents prion disease
EA Asante, M Smidak, A Grimshaw, R Houghton, A Tomlinson, A Jeelani, ...
Nature 522 (7557), 478-481, 2015
1272015
Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein
MK Sandberg, H Al-Doujaily, CJ Sigurdson, M Glatzel, C O'Malley, ...
The Journal of general virology 91 (Pt 10), 2651, 2010
1212010
Inherited prion disease with six octapeptide repeat insertional mutation—molecular analysis of phenotypic heterogeneity
S Mead, M Poulter, J Beck, TEF Webb, TA Campbell, JM Linehan, ...
Brain 129 (9), 2297-2317, 2006
1102006
A novel prion disease associated with diarrhea and autonomic neuropathy
S Mead, S Gandhi, J Beck, D Caine, D Gajulapalli, C Carswell, H Hyare, ...
New England Journal of Medicine 369 (20), 1904-1914, 2013
1092013
Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity
AJ Nicoll, S Panico, DB Freir, D Wright, C Terry, E Risse, CE Herron, ...
Nature communications 4 (1), 1-9, 2013
1092013
Phenotypic heterogeneity and genetic modification of P102L inherited prion disease in an international series
TEF Webb, M Poulter, J Beck, J Uphill, G Adamson, T Campbell, ...
Brain 131 (10), 2632-2646, 2008
1052008
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein
JDF Wadsworth, S Joiner, JM Linehan, S Cooper, C Powell, G Mallinson, ...
Brain 129 (6), 1557-1569, 2006
1002006
Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations
AF Hill, S Joiner, JA Beck, TA Campbell, A Dickinson, M Poulter, ...
Brain 129 (3), 676-685, 2006
992006
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