The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity DG Bowen, M Zen, L Holz, T Davis, GW McCaughan, P Bertolino The Journal of clinical investigation 114 (5), 701-712, 2004 | 329 | 2004 |
Liver-resident memory CD8+ T cells form a front-line defense against malaria liver-stage infection D Fernandez-Ruiz, WY Ng, LE Holz, JZ Ma, A Zaid, YC Wong, LS Lau, ... Immunity 45 (4), 889-902, 2016 | 212 | 2016 |
Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C G Ahlenstiel, B Edlich, LJ Hogdal, Y Rotman, M Noureddin, JJ Feld, ... Gastroenterology 141 (4), 1231-1239. e2, 2011 | 165 | 2011 |
Hepatocyte entry leads to degradation of autoreactive CD8 T cells V Benseler, A Warren, M Vo, LE Holz, SS Tay, DG Le Couteur, E Breen, ... Proceedings of the National Academy of Sciences 108 (40), 16735-16740, 2011 | 133 | 2011 |
Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death LE Holz, V Benseler, DG Bowen, P Bouillet, A Strasser, L O'Reilly, ... Gastroenterology 135 (3), 989-997, 2008 | 106 | 2008 |
A liver capsular network of monocyte-derived macrophages restricts hepatic dissemination of intraperitoneal bacteria by neutrophil recruitment F Sierro, M Evrard, S Rizzetto, M Melino, AJ Mitchell, M Florido, L Beattie, ... Immunity 47 (2), 374-388. e6, 2017 | 69 | 2017 |
Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury CS Viebahn, V Benseler, LE Holz, CL Elsegood, M Vo, P Bertolino, ... Journal of hepatology 53 (3), 500-507, 2010 | 61 | 2010 |
Early intrahepatic antigen‐specific retention of naïve CD8+ T cells is predominantly ICAM‐1/LFA‐1 dependent in mice P Bertolino, A Schrage, DG Bowen, K Klugewitz, S Ghani, K Eulenburg, ... Hepatology 42 (5), 1063-1071, 2005 | 57 | 2005 |
CD8+ T cell tolerance following antigen recognition on hepatocytes LE Holz, A Warren, DG Le Couteur, DG Bowen, P Bertolino Journal of autoimmunity 34 (1), 15-22, 2010 | 51 | 2010 |
T cell responses in hepatitis C virus infection: historical overview and goals for future research L Holz, B Rehermann Antiviral research 114, 96-105, 2015 | 40 | 2015 |
CD8+ T cell activation leads to constitutive formation of liver tissue-resident memory T cells that seed a large and flexible niche in the liver LE Holz, JE Prier, D Freestone, TM Steiner, K English, DN Johnson, ... Cell reports 25 (1), 68-79. e4, 2018 | 38 | 2018 |
B cell homeostasis in chronic hepatitis C virus–related mixed cryoglobulinemia is maintained through naïve B cell apoptosis LE Holz, JC Yoon, S Raghuraman, S Moir, MC Sneller, B Rehermann Hepatology 56 (5), 1602-1610, 2012 | 37 | 2012 |
Protective immunity to liver‐stage malaria LE Holz, D Fernandez‐Ruiz, WR Heath Clinical & translational immunology 5 (10), e105, 2016 | 36 | 2016 |
Immune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells MH Dahlke, R Loi, A Warren, L Holz, FC Popp, DJ Weiss, P Piso, ... Journal of hepatology 44 (2), 334-341, 2006 | 25 | 2006 |
Development of a novel CD4+ TCR transgenic line that reveals a dominant role for CD8+ dendritic cells and CD40 signaling in the generation of helper and CTL responses to blood … D Fernandez-Ruiz, LS Lau, N Ghazanfari, CM Jones, WY Ng, GM Davey, ... The Journal of Immunology 199 (12), 4165-4179, 2017 | 21 | 2017 |
Naive CD8 T cell activation by liver bone marrow-derived cells leads to a “neglected” IL-2low Bimhigh phenotype, poor CTL function and cell death LE Holz, V Benseler, M Vo, C McGuffog, N Van Rooijen, GW McCaughan, ... Journal of hepatology 57 (4), 830-836, 2012 | 21 | 2012 |
Mechanisms of T cell death in the liver: to Bim or not to Bim? LE Holz, DG Bowen, P Bertolino Digestive Diseases 28 (1), 14-24, 2010 | 21 | 2010 |
The pro‐fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride‐induced experimental liver injury XM Wang, LE Holz, S Chowdhury, SP Cordoba, KA Evans, MG Gall, ... Immunology and cell biology 95 (5), 443-453, 2017 | 17 | 2017 |
Dexamethasone inhibits IL-9 production by human T cells LE Holz, KP Jakobsen, J Van Snick, F Cormont, WA Sewell Journal of Inflammation 2 (1), 1-9, 2005 | 17 | 2005 |
Augmenting influenza-specific T cell memory generation with a natural killer T cell-dependent glycolipid–peptide vaccine RJ Anderson, J Li, L Kedzierski, BJ Compton, CM Hayman, TL Osmond, ... ACS chemical biology 12 (11), 2898-2905, 2017 | 16 | 2017 |