DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis J Bartkova, Z Hořejší, K Koed, A Krämer, F Tort, K Zieger, P Guldberg, ... Nature 434 (7035), 864-870, 2005 | 3252 | 2005 |
Poly (ADP-ribose)–dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1 D Ahel, Z Hořejší, N Wiechens, SE Polo, E Garcia-Wilson, I Ahel, H Flynn, ... science 325 (5945), 1240-1243, 2009 | 670 | 2009 |
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia A Adamo, SJ Collis, CA Adelman, N Silva, Z Horejsi, JD Ward, ... Molecular cell 39 (1), 25-35, 2010 | 341 | 2010 |
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex SJ Collis, A Ciccia, AJ Deans, Z Hořejší, JS Martin, SL Maslen, JM Skehel, ... Molecular cell 32 (3), 313-324, 2008 | 253 | 2008 |
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability Z Hořejší, H Takai, CA Adelman, SJ Collis, H Flynn, S Maslen, JM Skehel, ... Molecular cell 39 (6), 839-850, 2010 | 246 | 2010 |
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation Z Hořejší, J Falck, CJ Bakkenist, MB Kastan, J Lukas, J Bartek Oncogene 23 (17), 3122-3127, 2004 | 169 | 2004 |
HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis CA Adelman, RL Lolo, NJ Birkbak, O Murina, K Matsuzaki, Z Horejsi, ... Nature 502 (7471), 381-384, 2013 | 146 | 2013 |
Human RIF 1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation S Hiraga, T Ly, J Garzón, Z Hořejší, Y Ohkubo, A Endo, C Obuse, ... EMBO reports 18 (3), 403-419, 2017 | 144 | 2017 |
Cytokine expression and signaling in drug-induced cellular senescence Z Novakova, S Hubackova, M Kosar, L Janderova-Rossmeislova, ... Oncogene 29 (2), 273-284, 2010 | 144 | 2010 |
Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex Z Hořejší, L Stach, TG Flower, D Joshi, H Flynn, JM Skehel, NJ O’Reilly, ... Cell reports 7 (1), 19-26, 2014 | 99 | 2014 |
Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones A Malinová, Z Cvačková, D Matějů, Z Hořejší, C Abéza, F Vandermoere, ... Journal of Cell Biology 216 (6), 1579-1596, 2017 | 89 | 2017 |
Tripartite Motif-containing 33 (TRIM33) protein functions in the poly (ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver … A Kulkarni, J Oza, M Yao, H Sohail, V Ginjala, A Tomas-Loba, Z Horejsi, ... Journal of Biological Chemistry 288 (45), 32357-32369, 2013 | 77 | 2013 |
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations A Konopka, DR Whelan, MS Jamali, E Perri, H Shahheydari, RP Toth, ... Molecular neurodegeneration 15, 1-28, 2020 | 74 | 2020 |
MRE11 stability is regulated by CK2-dependent interaction with R2TP complex P von Morgen, K Burdova, TG Flower, NJ O'Reilly, SJ Boulton, ... Oncogene 36 (34), 4943-4950, 2017 | 45 | 2017 |
Substrate recognition and function of the R2TP complex in response to cellular stress P von Morgen, Z Hořejší, L Macurek Frontiers in genetics 6, 69, 2015 | 43 | 2015 |
The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma P Pajer, V Pečenka, V Karafiát, J Kralova, Z Hořejší, M Dvořák Oncogene 22 (5), 665-673, 2003 | 31 | 2003 |
Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal P von Morgen, T Lidak, Z Horejsi, L Macurek Biology of the Cell 110 (6), 137-146, 2018 | 22 | 2018 |
FANCM-FAAP24 and HCLK2: roles in ATR signalling and the Fanconi anemia pathway Z Hořejší, SJ Collis, SJ Boulton Cell Cycle 8 (8), 1133-1137, 2009 | 20 | 2009 |
Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase A Dullovi, M Ozgencil, V Rajvee, WY Tse, PR Cutillas, SA Martin, ... Iscience 26 (3), 2023 | 4 | 2023 |
The linker histone H1–BRCA1 axis is a crucial mediator of replication fork stability M Ozgencil, A Dullovi, RCC Higos, Z Hořejší, R Bellelli Life Science Alliance 6 (9), 2023 | 1 | 2023 |