| Induction of the interferon response by siRNA is cell type–and duplex length–dependent A Reynolds, EM Anderson, A Vermeulen, Y Fedorov, K Robinson, ... Rna 12 (6), 988-993, 2006 | 445 | 2006 |
| The contributions of dsRNA structure to Dicer specificity and efficiency A Vermeulen, L Behlen, A Reynolds, A Wolfson, WS Marshall, ... Rna 11 (5), 674-682, 2005 | 399 | 2005 |
| Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells A Schoolmeesters, T Eklund, D Leake, A Vermeulen, Q Smith, ... PloS one 4 (5), e5605, 2009 | 230 | 2009 |
| Systematic analysis of CRISPR–Cas9 mismatch tolerance reveals low levels of off-target activity EM Anderson, A Haupt, JA Schiel, E Chou, HB Machado, Ž Strezoska, ... Journal of biotechnology 211, 56-65, 2015 | 189 | 2015 |
| Double-stranded regions are essential design components of potent inhibitors of RISC function A Vermeulen, B Robertson, AB Dalby, WS Marshall, J Karpilow, D Leake, ... Rna 13 (5), 723-730, 2007 | 160 | 2007 |
| Combined agonist–antagonist genome-wide functional screening identifies broadly active antiviral microRNAs D Santhakumar, T Forster, NN Laqtom, R Fragkoudis, P Dickinson, ... Proceedings of the National Academy of Sciences 107 (31), 13830-13835, 2010 | 131 | 2010 |
| Determining DNA global structure and DNA bending by application of NMR residual dipolar couplings A Vermeulen, H Zhou, A Pardi Journal of the American Chemical Society 122 (40), 9638-9647, 2000 | 119 | 2000 |
| Specificity and functionality of microRNA inhibitors B Robertson, AB Dalby, J Karpilow, A Khvorova, D Leake, A Vermeulen Silence 1, 1-9, 2010 | 102 | 2010 |
| Versatility of chemically synthesized guide RNAs for CRISPR-Cas9 genome editing ML Kelley, Ž Strezoska, K He, A Vermeulen, A van Brabant Smith Journal of biotechnology 233, 74-83, 2016 | 100 | 2016 |
| Comparison of the Global Structure and Dynamics of Native and Unmodified tRNAval A Vermeulen, SA McCallum, A Pardi Biochemistry 44 (16), 6024-6033, 2005 | 73 | 2005 |
| Incorporating residual dipolar couplings into the NMR solution structure determination of nucleic acids H Zhou, A Vermeulen, FM Jucker, A Pardi Biopolymers: Original Research on Biomolecules 52 (4), 168-180, 1999 | 60 | 1999 |
| Highly functional short hairpin RNA A Vermeulen, A Reynolds, J Karpilow, D Leake, X Cheng, S Hartsel, ... US Patent App. 11/390,829, 2006 | 46 | 2006 |
| Gene expression profiling in pachyonychia congenita skin YA Cao, RP Hickerson, BL Seegmiller, D Grapov, MM Gross, MR Bessette, ... Journal of dermatological science 77 (3), 156-165, 2015 | 42 | 2015 |
| Duplex oligonucleotides with enhanced functionality in gene regulation A Khvorova, D Leake, B Robertson, A Vermeulen, C Yamada US Patent 8,188,060, 2012 | 42 | 2012 |
| Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens Ž Strezoska, A Licon, J Haimes, KJ Spayd, KM Patel, K Sullivan, ... Public Library of Science 7 (8), e42341, 2012 | 41 | 2012 |
| High-content analysis screening for cell cycle regulators using arrayed synthetic crRNA libraries Ž Strezoska, MR Perkett, ET Chou, E Maksimova, EM Anderson, ... Journal of biotechnology 251, 189-200, 2017 | 33 | 2017 |
| Functional screening identifies human miRNAs that modulate adenovirus propagation in prostate cancer cells J Hodzic, D Sie, A Vermeulen, VW Van Beusechem Human Gene Therapy 28 (9), 766-780, 2017 | 30 | 2017 |
| Compositions and methods for inhibiting gene silencing by rna interference A Vermeulen, B Robertson, S Baskerville, C Yamada, D Leake, Y Fedorov, ... US Patent App. 12/279,594, 2010 | 16 | 2010 |
| CRISPR-mediated transcriptional activation with synthetic guide RNA Ž Strezoska, SM Dickerson, E Maksimova, E Chou, MM Gross, K Hemphill, ... Journal of Biotechnology 319, 25-35, 2020 | 15* | 2020 |
| Minor groove binder (MGB)-oligonucleotide miRNA antagonists A Khvorova, A Vermeulen, R Kaiser, J Karpilow, NMJ Vermeulen, ... US Patent 9,334,495, 2016 | 14 | 2016 |
