Pathogenesis of human systemic lupus erythematosus: a cellular perspective VR Moulton, A Suarez-Fueyo, E Meidan, H Li, M Mizui, GC Tsokos Trends in molecular medicine 23 (7), 615-635, 2017 | 414 | 2017 |
Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis N Takegahara, H Takamatsu, T Toyofuku, T Tsujimura, T Okuno, ... Nature cell biology 8 (6), 615-622, 2006 | 299 | 2006 |
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II H Takamatsu, N Takegahara, Y Nakagawa, M Tomura, M Taniguchi, ... Nature immunology 11 (7), 594-600, 2010 | 234 | 2010 |
CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance T Koga, CM Hedrich, M Mizui, N Yoshida, K Otomo, LA Lieberman, ... The Journal of clinical investigation 124 (5), 2234-2245, 2014 | 205 | 2014 |
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice A Kumanogoh, T Shikina, K Suzuki, S Uematsu, K Yukawa, ... Immunity 22 (3), 305-316, 2005 | 194 | 2005 |
The CD38/NAD/SIRTUIN1/EZH2 axis mitigates cytotoxic CD8 T cell function and identifies patients with SLE prone to infections E Katsuyama, A Suarez-Fueyo, SJ Bradley, M Mizui, AV Marin, L Mulki, ... Cell reports 30 (1), 112-123. e4, 2020 | 131 | 2020 |
Exploring RNA interference as a therapeutic strategy for renal disease Y Takabatake, Y Isaka, M Mizui, H Kawachi, F Shimizu, T Ito, M Hori, ... Gene therapy 12 (12), 965-973, 2005 | 131 | 2005 |
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ... Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012 | 125 | 2012 |
IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4− CD8− IL-17–producing T cells M Mizui, T Koga, LA Lieberman, J Beltran, N Yoshida, MC Johnson, ... The Journal of Immunology 193 (5), 2168-2177, 2014 | 116 | 2014 |
Plexin-A4 negatively regulates T lymphocyte responses M Yamamoto, K Suzuki, T Okuno, T Ogata, N Takegahara, H Takamatsu, ... International immunology 20 (3), 413-420, 2008 | 113 | 2008 |
Calcium/calmodulin-dependent protein kinase IV suppresses IL-2 production and regulatory T cell activity in lupus T Koga, K Ichinose, M Mizui, JC Crispín, GC Tsokos The Journal of Immunology 189 (7), 3490-3496, 2012 | 111 | 2012 |
The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal … K Sunahori, K Nagpal, CM Hedrich, M Mizui, LM Fitzgerald, GC Tsokos Journal of Biological Chemistry 288 (30), 21936-21944, 2013 | 103 | 2013 |
Antisense oligonucleotides against thrombospondin-1 inhibit activation of TGF-β in fibrotic renal disease in the rat in vivo C Daniel, Y Takabatake, M Mizui, Y Isaka, H Kawashi, H Rupprecht, ... The American journal of pathology 163 (3), 1185-1192, 2003 | 98 | 2003 |
Bimodal regulation of T cell-mediated immune responses by TIM-4 M Mizui, T Shikina, H Arase, K Suzuki, T Yasui, PD Rennert, ... International immunology 20 (5), 695-708, 2008 | 91 | 2008 |
Signal transducer and activator of transcription (STAT) 3 inhibition delays the onset of lupus nephritis in MRL/lpr mice LJ Edwards, M Mizui, V Kyttaris Clinical immunology 158 (2), 221-230, 2015 | 82 | 2015 |
Requirement for CD100–CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment A Kumanogoh, T Shikina, C Watanabe, N Takegahara, K Suzuki, ... International immunology 17 (10), 1277-1282, 2005 | 81 | 2005 |
ICER is requisite for Th17 differentiation N Yoshida, D Comte, M Mizui, K Otomo, F Rosetti, TN Mayadas, ... Nature communications 7 (1), 12993, 2016 | 80 | 2016 |
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity MJ Massaad, J Zhou, D Tsuchimoto, J Chou, H Jabara, E Janssen, ... The Journal of Clinical Investigation 126 (11), 4219-4236, 2016 | 78 | 2016 |
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus J Wang, M Mizui, LF Zeng, R Bronson, M Finnell, C Terhorst, VC Kyttaris, ... The Journal of clinical investigation 126 (6), 2077-2092, 2016 | 76 | 2016 |
Targeting regulatory T cells to treat patients with systemic lupus erythematosus M Mizui, GC Tsokos Frontiers in immunology 9, 359136, 2018 | 74 | 2018 |