Nicole van der Weerden
Nicole van der Weerden
La Trobe Institute for Molecular Science; Hexima Limited
Verified email at latrobe.edu.au
TitleCited byYear
Method of treatment
NL van Der Weerden, MA Anderson
US Patent 10,010,576, 2018
2282018
The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae
NL Van Der Weerden, FT Lay, MA Anderson
Journal of Biological Chemistry 283 (21), 14445-14452, 2008
1702008
Properties and mechanisms of action of naturally occurring antifungal peptides
NL Van der Weerden, MR Bleackley, MA Anderson
Cellular and molecular life sciences 70 (19), 3545-3570, 2013
1502013
Permeabilization of fungal hyphae by the plant defensin NaD1 occurs through a cell wall-dependent process
NL van der Weerden, REW Hancock, MA Anderson
Journal of Biological Chemistry 285 (48), 37513-37520, 2010
1412010
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
IKH Poon, AA Baxter, FT Lay, GD Mills, CG Adda, JAE Payne, TK Phan, ...
Elife 3, e01808, 2014
1012014
Plant defensins: common fold, multiple functions
NL Van der Weerden, MA Anderson
Fungal Biology Reviews 26 (4), 121-131, 2013
1002013
Identification and mechanism of action of the plant defensin NaD1 as a new member of the antifungal drug arsenal against Candida albicans
BME Hayes, MR Bleackley, JL Wiltshire, MA Anderson, A Traven, ...
Antimicrobial agents and chemotherapy 57 (8), 3667-3675, 2013
812013
Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase
KS Harris, T Durek, Q Kaas, AG Poth, EK Gilding, BF Conlan, I Saska, ...
Nature communications 6, 10199, 2015
772015
Dimerization of plant defensin NaD1 enhances its antifungal activity
FT Lay, GD Mills, IKH Poon, NP Cowieson, N Kirby, AA Baxter, ...
Journal of Biological Chemistry 287 (24), 19961-19972, 2012
672012
Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins
BME Hayes, MA Anderson, A Traven, NL van der Weerden, MR Bleackley
Cellular and molecular life sciences 71 (14), 2651-2666, 2014
522014
Cyclotides are a component of the innate defense of Oldenlandia affinis
JS Mylne, CK Wang, NL van der Weerden, DJ Craik
Peptide Science 94 (5), 635-646, 2010
422010
The evolution, function and mechanisms of action for plant defensins
K Parisi, TMA Shafee, P Quimbar, NL van der Weerden, MR Bleackley, ...
Seminars in cell & developmental biology, 2018
382018
The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4, 5 bisphosphate
JAE Payne, MR Bleackley, TH Lee, TMA Shafee, IKH Poon, MD Hulett, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (6), 1099-1109, 2016
322016
Inhibition of cereal rust fungi by both class I and II defensins derived from the flowers of Nicotiana alata
PM Dracatos, NL Van der Weerden, KT Carroll, ED Johnson, ...
Molecular plant pathology 15 (1), 67-79, 2014
242014
Agp2p, the plasma membrane transregulator of polyamine uptake, regulates the antifungal activities of the plant defensin NaD1 and other cationic peptides
MR Bleackley, JL Wiltshire, F Perrine-Walker, S Vasa, RL Burns, ...
Antimicrobial agents and chemotherapy 58 (5), 2688-2698, 2014
222014
Modified plant defensins useful as anti-pathogenic agents
N van der Weerden, MA Anderson
US Patent App. 10/174,339, 2019
172019
Nicotiana alata defensin chimeras reveal differences in the mechanism of fungal and tumor cell killing and an enhanced antifungal variant
MR Bleackley, JAE Payne, BME Hayes, T Durek, DJ Craik, TMA Shafee, ...
Antimicrobial agents and chemotherapy 60 (10), 6302-6312, 2016
172016
Antifungal methods
M Anderson, R Heath, J McKenna, N van der Weerden
US Patent App. 12/362,657, 2009
152009
Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta
S Poon, KS Harris, MA Jackson, OC McCorkelle, EK Gilding, T Durek, ...
Journal of experimental botany 69 (3), 633-641, 2017
132017
A radish seed antifungal peptide with a high amyloid fibril-forming propensity
M Garvey, S Meehan, SL Gras, HJ Schirra, DJ Craik, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (8), 1615-1623, 2013
132013
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