Brent Segelke
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Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove
ZH Zeng, AR Castano, BW Segelke, EA Stura, PA Peterson, IA Wilson
Science 277 (5324), 339-345, 1997
Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, ape1: implications for the catalytic mechanism1
PT Beernink, BW Segelke, MZ Hadi, JP Erzberger, DM Wilson Iii, B Rupp
Journal of molecular biology 307 (4), 1023-1034, 2001
The CD1 family of lipid antigen-presenting molecules
SA Porcelli, BW Segelke, M Sugita, IA Wilson, MB Brenner
Immunology today 19 (8), 362-368, 1998
Fixed-target protein serial microcrystallography with an x-ray free electron laser
MS Hunter, B Segelke, M Messerschmidt, GJ Williams, NA Zatsepin, ...
Scientific reports 4, 6026, 2014
Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles
JA Cappuccio, CD Blanchette, TA Sulchek, ES Arroyo, JM Kralj, AK Hinz, ...
Molecular & Cellular Proteomics 7 (11), 2246-2253, 2008
Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism
S Chan, B Segelke, T Lekin, H Krupka, US Cho, M Kim, M So, CY Kim, ...
Journal of molecular biology 341 (2), 503-517, 2004
Different apolipoproteins impact nanolipoprotein particle formation
BA Chromy, E Arroyo, CD Blanchette, G Bench, H Benner, JA Cappuccio, ...
Journal of the American Chemical Society 129 (46), 14348-14354, 2007
Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity
B Segelke, M Knapp, S Kadkhodayan, R Balhorn, B Rupp
Proceedings of the National Academy of Sciences of the United States of …, 2004
Interaction of the N-terminal domain of apolipoprotein E4 with heparin
J Dong, CA Peters-Libeu, KH Weisgraber, BW Segelke, B Rupp, I Capila, ...
Biochemistry 40 (9), 2826-2834, 2001
Efficiency analysis of sampling protocols used in protein crystallization screening
BW Segelke
Journal of crystal growth 232 (1-4), 553-562, 2001
The TB structural genomics consortium crystallization facility: towards automation from protein to electron density
B Rupp, BW Segelke, HI Krupka, T Lekin, J Schäfer, A Zemla, D Toppani, ...
Acta Crystallographica Section D: Biological Crystallography 58 (10), 1514-1518, 2002
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin
S Li, NA Peterson, MY Kim, CY Kim, LW Hung, M Yu, T Lekin, ...
Journal of molecular biology 346 (4), 1035-1046, 2005
Femtosecond X-ray diffraction from two-dimensional protein crystals
M Frank, DB Carlson, MS Hunter, GJ Williams, M Messerschmidt, ...
IUCrJ 1 (2), 95-100, 2014
Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing1
BW Segelke, D Nguyen, R Chee, NH Xuong, EA Dennis
Journal of molecular biology 279 (1), 223-232, 1998
Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations
CD Blanchette, R Law, WH Benner, JB Pesavento, JA Cappuccio, ...
Journal of lipid research 49 (7), 1420-1430, 2008
The high-speed Hydra-Plus-One system for automated high-throughput protein crystallography
HI Krupka, B Rupp, BW Segelke, T Lekin, D Wright, HC Wu, P Todd, ...
Acta Crystallographica Section D: Biological Crystallography 58 (10), 1523-1526, 2002
High-throughput, fluorescence-based screening for soluble protein expression
MA Coleman, VH Lao, BW Segelke, PT Beernink
Journal of proteome research 3 (5), 1024-1032, 2004
Effective electron-density map improvement and structure validation on a Linux multi-CPU web cluster: The TB Structural Genomics Consortium Bias Removal Web Service
V Reddy, S Swanson, B Segelke, KA Kantardjieff, JC Sacchettini, B Rupp
Acta Crystallographica Section D: Biological Crystallography 59 (12), 2200-2210, 2003
Concanavalin A in a dimeric crystal form: revisiting structural accuracy and molecular flexibility
KA Kantardjieff, P HoÈchtl, BW Segelke, FM Tao, B Rupp
Acta Crystallographica Section D: Biological Crystallography 58 (5), 735-743, 2002
Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding
BW Segelke, M Forstner, M Knapp, SD Trakhanov, S Parkin, ...
Protein Science 9 (5), 886-897, 2000
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Articles 1–20