| Are animal models useful for studying human disc disorders/degeneration? M Alini, SM Eisenstein, K Ito, C Little, AA Kettler, K Masuda, J Melrose, ... European Spine Journal 17, 2-19, 2008 | 830 | 2008 |
| Diverse cell signaling events modulated by perlecan JM Whitelock, J Melrose, RV Iozzo Biochemistry 47 (43), 11174-11183, 2008 | 313 | 2008 |
| Increased nerve and blood vessel ingrowth associated with proteoglycan depletion in an ovine anular lesion model of experimental disc degeneration J Melrose, S Roberts, S Smith, J Menage, P Ghosh Spine 27 (12), 1278-1285, 2002 | 249 | 2002 |
| Proteoglycan degradation by the ADAMTS family of proteinases H Stanton, J Melrose, CB Little, AJ Fosang Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (12 …, 2011 | 243 | 2011 |
| Keratan sulfate, a complex glycosaminoglycan with unique functional capability B Caterson, J Melrose Glycobiology 28 (4), 182-206, 2018 | 216 | 2018 |
| Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis AA Young, S McLennan, MM Smith, SM Smith, MA Cake, RA Read, ... Arthritis research & therapy 8, 1-6, 2006 | 198 | 2006 |
| Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors S Knox, C Merry, S Stringer, J Melrose, J Whitelock Journal of Biological Chemistry 277 (17), 14657-14665, 2002 | 197 | 2002 |
| A comparative analysis of the differential spatial and temporal distributions of the large (aggrecan, versican) and small (decorin, biglycan, fibromodulin) proteoglycans of the … J Melrose, P Ghosh, TKF Taylor The Journal of Anatomy 198 (1), 3-15, 2001 | 190 | 2001 |
| Increased synthesis of matrix metalloproteinases by aortic smooth muscle cells is implicated in the etiopathogenesis of abdominal aortic aneurysms MI Patel, J Melrose, P Ghosh, M Appleberg Journal of vascular surgery 24 (1), 82-92, 1996 | 169 | 1996 |
| Comparative spatial and temporal localisation of perlecan, aggrecan and type I, II and IV collagen in the ovine meniscus: an ageing study J Melrose, S Smith, M Cake, R Read, J Whitelock Histochemistry and cell biology 124, 225-235, 2005 | 160 | 2005 |
| Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells JM Whitelock, LD Graham, J Melrose, AD Murdoch, RV Iozzo, ... Matrix biology 18 (2), 163-178, 1999 | 159 | 1999 |
| A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus J Melrose, P Ghosh, TKF Taylor, A Hall, OL Osti, B Vernon‐Roberts, ... Journal of orthopaedic research 10 (5), 665-676, 1992 | 153 | 1992 |
| Aggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral disc J Melrose, SM Smith, RC Appleyard, CB Little European Spine Journal 17, 314-324, 2008 | 144 | 2008 |
| Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically … J Melrose, ES Fuller, PJ Roughley, MM Smith, B Kerr, CE Hughes, ... Arthritis research & therapy 10, 1-10, 2008 | 142 | 2008 |
| Cancer metastasis: the role of the extracellular matrix and the heparan sulfate proteoglycan perlecan Z Elgundi, M Papanicolaou, G Major, TR Cox, J Melrose, JM Whitelock, ... Frontiers in oncology 9, 1482, 2020 | 139 | 2020 |
| The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling MS Lord, CY Chuang, J Melrose, MJ Davies, RV Iozzo, JM Whitelock Matrix Biology 35, 112-122, 2014 | 136 | 2014 |
| Multifidus muscle changes after back injury are characterized by structural remodeling of muscle, adipose and connective tissue, but not muscle atrophy: molecular and … PW Hodges, G James, L Blomster, L Hall, A Schmid, C Shu, C Little, ... Spine 40 (14), 1057-1071, 2015 | 135 | 2015 |
| Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan CY Chuang, MS Lord, J Melrose, MD Rees, SM Knox, C Freeman, ... Biochemistry 49 (26), 5524-5532, 2010 | 135 | 2010 |
| Induction of matrix metalloproteinase-2 and-3 activity in ovine nucleus pulposus cells grown in three-dimensional agarose gel culture by interleukin-1β: a potential pathway of … B Shen, J Melrose, P Ghosh, T Taylor European Spine Journal 12, 66-75, 2003 | 133 | 2003 |
| The structure, location, and function of perlecan, a prominent pericellular proteoglycan of fetal, postnatal, and mature hyaline cartilages J Melrose, P Roughley, S Knox, S Smith, M Lord, J Whitelock Journal of biological chemistry 281 (48), 36905-36914, 2006 | 126 | 2006 |
Christopher LittleProfessor of Surgery, University of SydneyVerified email at sydney.edu.au
