Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters TE Sweeney, TD Azad, M Donato, WA Haynes, TM Perumal, R Henao, ... Critical care medicine 46 (6), 915, 2018 | 85 | 2018 |
A community approach to mortality prediction in sepsis via gene expression analysis TE Sweeney, TM Perumal, R Henao, M Nichols, JA Howrylak, AM Choi, ... Nature communications 9 (1), 1-10, 2018 | 82 | 2018 |
A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia GP Parnell, AS McLean, DR Booth, NJ Armstrong, M Nalos, SJ Huang, ... Critical Care 16 (4), 1-12, 2012 | 79 | 2012 |
Identifying key regulatory genes in the whole blood of septic patients to monitor underlying immune dysfunctions GP Parnell, BM Tang, M Nalos, NJ Armstrong, SJ Huang, DR Booth, ... Shock 40 (3), 166-174, 2013 | 68 | 2013 |
Immune effects of interferon gamma in persistent staphylococcal sepsis M Nalos, B Santner-Nanan, G Parnell, B Tang, AS McLean, R Nanan American journal of respiratory and critical care medicine 185 (1), 110-112, 2012 | 67 | 2012 |
Aberrant cell cycle and apoptotic changes characterise severe influenza A infection–a meta-analysis of genomic signatures in circulating leukocytes G Parnell, A McLean, D Booth, S Huang, M Nalos, B Tang Plos one 6 (3), e17186, 2011 | 61 | 2011 |
The multiple sclerosis (MS) genetic risk factors indicate both acquired and innate immune cell subsets contribute to MS pathogenesis and identify novel therapeutic opportunities GP Parnell, DR Booth Frontiers in immunology 8, 425, 2017 | 60 | 2017 |
Fetal–maternal alignment of regulatory T cells correlates with IL-10 and Bcl-2 upregulation in pregnancy B Santner-Nanan, K Straubinger, P Hsu, G Parnell, B Tang, B Xu, ... The Journal of Immunology 191 (1), 145-153, 2013 | 48 | 2013 |
Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection BM Tang, M Shojaei, S Teoh, A Meyers, J Ho, TB Ball, Y Keynan, ... Nature communications 10 (1), 1-13, 2019 | 44 | 2019 |
The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease GP Parnell, PN Gatt, M Krupa, D Nickles, FC McKay, SD Schibeci, ... Clinical immunology 151 (1), 16-24, 2014 | 44 | 2014 |
The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells F Shahijanian, GP Parnell, FC McKay, PN Gatt, M Shojoei, KS O'Connor, ... Human molecular genetics 23 (6), 1425-1434, 2014 | 43 | 2014 |
Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases DR Booth, N Ding, GP Parnell, F Shahijanian, S Coulter, SD Schibeci, ... Genes & Immunity 17 (4), 213-219, 2016 | 40 | 2016 |
A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection BM Tang, M Shojaei, GP Parnell, S Huang, M Nalos, S Teoh, K O'Connor, ... European Respiratory Journal 49 (6), 2017 | 37 | 2017 |
The MS risk allele of CD40 is associated with reduced cell-membrane bound expression in antigen presenting cells: implications for gene function J Field, F Shahijanian, S Schibeci, ... PloS one 10 (6), e0127080, 2015 | 28 | 2015 |
The antiviral role of zinc and metallothioneins in hepatitis C infection SA Read, G Parnell, D Booth, MW Douglas, J George, G Ahlenstiel Journal of viral hepatitis 25 (5), 491-501, 2018 | 22 | 2018 |
Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent KS O'Connor, G Parnell, E Patrick, G Ahlenstiel, V Suppiah, ... Genes & Immunity 15 (2), 88-94, 2014 | 20 | 2014 |
The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis NL Fewings, PN Gatt, FC McKay, GP Parnell, SD Schibeci, J Edwards, ... Journal of autoimmunity 78, 57-69, 2017 | 18 | 2017 |
Transcriptional reprogramming of metabolic pathways in critically ill patients M Nalos, G Parnell, R Robergs, D Booth, AS McLean, BM Tang Intensive care medicine experimental 4 (1), 1-15, 2016 | 16 | 2016 |
The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies FC McKay, PN Gatt, N Fewings, GP Parnell, SD Schibeci, MAI Basuki, ... Clinical Immunology 163, 96-107, 2016 | 16 | 2016 |
Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season GP Parnell, PN Gatt, FC McKay, S Schibeci, M Krupa, JE Powell, ... Multiple Sclerosis Journal 20 (6), 675-685, 2014 | 16 | 2014 |