| ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 A Hutloff, AM Dittrich, KC Beier, B Eljaschewitsch, R Kraft, ... Nature 402 (Suppl 6763), 21-24, 1999 | 2070 | 1999 |
| Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency B Grimbacher, A Hutloff, M Schlesier, E Glocker, K Warnatz, R Dräger, ... Nature immunology 4 (3), 261-268, 2003 | 894 | 2003 |
| Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells BG Dorner, MB Dorner, X Zhou, C Opitz, A Mora, S Güttler, A Hutloff, ... Immunity 31 (5), 823-833, 2009 | 476 | 2009 |
| Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA DI Yu, AHM Tan, X Hu, V Athanasopoulos, N Simpson, DG Silva, A Hutloff, ... Nature 450 (7167), 299-303, 2007 | 476 | 2007 |
| ICOS controls the pool size of effector-memory and regulatory T cells Y Burmeister, T Lischke, AC Dahler, HW Mages, KP Lam, AJ Coyle, ... The Journal of Immunology 180 (2), 774-782, 2008 | 332 | 2008 |
| Expression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 M Löhning, A Hutloff, T Kallinich, HW Mages, K Bonhagen, A Radbruch, ... The Journal of experimental medicine 197 (2), 181-193, 2003 | 330 | 2003 |
| ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2 JP Weber, F Fuhrmann, RK Feist, A Lahmann, MS Al Baz, LJ Gentz, ... Journal of Experimental Medicine 212 (2), 217-233, 2015 | 323 | 2015 |
| ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells S Khayyamian, A Hutloff, K Büchner, M Gräfe, V Henn, RA Kroczek, ... Proceedings of the National Academy of Sciences 99 (9), 6198-6203, 2002 | 318 | 2002 |
| Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand HW Mages, A Hutloff, C Heuck, K Büchner, H Himmelbauer, F Oliveri, ... European journal of immunology 30 (4), 1040-1047, 2000 | 299 | 2000 |
| Induction, binding specificity and function of human ICOS KC Beier, A Hutloff, AM Dittrich, C Heuck, A Rauch, K Büchner, B Ludewig, ... European journal of immunology 30 (12), 3707-3717, 2000 | 283 | 2000 |
| Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus A Hutloff, K Büchner, K Reiter, HJ Baelde, M Odendahl, A Jacobi, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2004 | 264 | 2004 |
| LAG-3 inhibitory receptor expression identifies immunosuppressive natural regulatory plasma cells AC Lino, V Lampropoulou, A Welle, J Joedicke, J Pohar, Q Simon, ... Immunity 49 (1), 120-133. e9, 2018 | 229 | 2018 |
| Emerging paradigms of T-cell co-stimulation RA Kroczek, HW Mages, A Hutloff Current opinion in immunology 16 (3), 321-327, 2004 | 203 | 2004 |
| Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS MA Linterman, RJ Rigby, R Wong, D Silva, D Withers, G Anderson, ... Immunity 30 (2), 228-241, 2009 | 166 | 2009 |
| ICOS and CD28 reversely regulate IL‐10 on re‐activation of human effector T cells with mature dendritic cells EJ Witsch, M Peiser, A Hutloff, K Büchner, BG Dorner, H Jonuleit, ... European journal of immunology 32 (9), 2680-2686, 2002 | 164 | 2002 |
| Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses M Ugolini, J Gerhard, S Burkert, KJ Jensen, P Georg, F Ebner, SM Volkers, ... Nature immunology 19 (4), 386-396, 2018 | 151 | 2018 |
| T‐follicular helper cells survive as long‐term memory cells JP Weber, F Fuhrmann, A Hutloff European journal of immunology 42 (8), 1981-1988, 2012 | 136 | 2012 |
| Tolerance induction with T cell–dependent protein antigens induces regulatory sialylated IgGs CM Oefner, A Winkler, C Hess, AK Lorenz, V Holecska, M Huxdorf, ... Journal of Allergy and Clinical Immunology 129 (6), 1647-1655. e13, 2012 | 131 | 2012 |
| MicroRNA-146a regulates ICOS–ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres A Pratama, M Srivastava, NJ Williams, I Papa, SK Lee, XT Dinh, A Hutloff, ... Nature communications 6 (1), 6436, 2015 | 126 | 2015 |
| Induction of potent CD8 T cell cytotoxicity by specific targeting of antigen to cross-presenting dendritic cells in vivo via murine or human XCR1 E Hartung, M Becker, A Bachem, N Reeg, A Jäkel, A Hutloff, H Weber, ... The Journal of Immunology 194 (3), 1069-1079, 2015 | 119 | 2015 |
