|Alzheimer disease: amyloidogenesis, the presenilins and animal models|
M Newman, FI Musgrave, M Lardelli
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (3), 285-297, 2007
|Using the zebrafish model for Alzheimer’s disease research|
M Newman, E Ebrahimie, M Lardelli
Frontiers in genetics 5, 189, 2014
|Evaluation of color preference in zebrafish for learning and memory|
A Avdesh, MT Martin-Iverson, A Mondal, M Chen, S Askraba, N Morgan, ...
Journal of Alzheimer's Disease 28 (2), 459-469, 2012
|Zebrafish as a tool in Alzheimer's disease research|
M Newman, G Verdile, RN Martins, M Lardelli
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (3), 346-352, 2011
|Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity|
S Nornes, M Newman, G Verdile, S Wells, CL Stoick-Cooper, B Tucker, ...
Human molecular genetics 17 (3), 402-412, 2008
|Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease|
M Newman, L Wilson, G Verdile, A Lim, I Khan, SH Moussavi Nik, ...
Human molecular genetics 23 (3), 602-617, 2014
|The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress|
SH Moussavi Nik, L Wilson, M Newman, K Croft, TA Mori, I Musgrave, ...
Journal of Alzheimer's Disease 28 (3), 515-530, 2012
|Intraspinal sensory neurons provide powerful inhibition to motor circuits ensuring postural control during locomotion|
JM Hubbard, UL Böhm, A Prendergast, PEB Tseng, M Newman, C Stokes, ...
Current Biology 26 (21), 2841-2853, 2016
|Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos|
S Nornes, M Newman, S Wells, G Verdile, RN Martins, M Lardelli
Experimental cell research 315 (16), 2791-2801, 2009
|The guinea pig as a model for sporadic Alzheimer’s disease (AD): the impact of cholesterol intake on expression of AD-related genes|
MJ Sharman, SH Moussavi Nik, MM Chen, D Ong, L Wijaya, SM Laws, ...
PLoS One 8 (6), e66235, 2013
|Evidence for and against a pathogenic role of reduced γ-secretase activity in familial Alzheimer’s disease|
T Jayne, M Newman, G Verdile, G Sutherland, G Münch, I Musgrave, ...
Journal of Alzheimer's Disease 52 (3), 781-799, 2016
|Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity|
SH Moussavi Nik, M Newman, L Wilson, E Ebrahimie, S Wells, I Musgrave, ...
Human molecular genetics 24 (13), 3662-3678, 2015
|The response of HMGA1 to changes in oxygen availability is evolutionarily conserved|
SHM Nik, M Newman, M Lardelli
Experimental cell research 317 (11), 1503-1512, 2011
|Dysregulation of neuronal iron homeostasis as an alternative unifying effect of mutations causing familial Alzheimer’s disease|
AL Lumsden, JT Rogers, S Majd, M Newman, GT Sutherland, G Verdile, ...
Frontiers in neuroscience 12, 533, 2018
|Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis|
M Newman, B Tucker, S Nornes, A Ward, M Lardelli
Journal of Alzheimer's Disease 16 (1), 133-147, 2009
|A zebrafish melanophore model of amyloidβ toxicity|
M Newman, L Wilson, E Camp, G Verdile, R Martins, M Lardelli
Zebrafish 7 (2), 155-159, 2010
|Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production|
M Newman, N Hin, S Pederson, M Lardelli
Molecular brain 12 (1), 1-5, 2019
|Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy|
MA Corbett, CL van Eyk, DL Webber, SJ Bent, M Newman, K Harper, ...
NPJ genomic medicine 3 (1), 1-9, 2018
|Alternative splicing in a presenilin 2 variant associated with Alzheimer disease|
JE Braggin, SA Bucks, MM Course, CL Smith, B Sopher, L Osnis, ...
Annals of clinical and translational neurology 6 (4), 762-777, 2019
|Animal models of Alzheimer’s disease|
M Newman, D Kretzschmar, I Khan, M Chen, G Verdile, M Lardelli
Animal models for the study of human disease, 1031-1085, 2017