Alzheimer disease: amyloidogenesis, the presenilins and animal models M Newman, FI Musgrave, M Lardelli Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (3), 285-297, 2007 | 163 | 2007 |
Using the zebrafish model for Alzheimer’s disease research M Newman, E Ebrahimie, M Lardelli Frontiers in genetics 5, 189, 2014 | 126 | 2014 |
Evaluation of color preference in zebrafish for learning and memory A Avdesh, MT Martin-Iverson, A Mondal, M Chen, S Askraba, N Morgan, ... Journal of Alzheimer's Disease 28 (2), 459-469, 2012 | 123 | 2012 |
Zebrafish as a tool in Alzheimer's disease research M Newman, G Verdile, RN Martins, M Lardelli Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (3), 346-352, 2011 | 77 | 2011 |
Intraspinal sensory neurons provide powerful inhibition to motor circuits ensuring postural control during locomotion JM Hubbard, UL Böhm, A Prendergast, PEB Tseng, M Newman, C Stokes, ... Current Biology 26 (21), 2841-2853, 2016 | 54 | 2016 |
The BACE1-PSEN-AβPP regulatory axis has an ancient role in response to low oxygen/oxidative stress SH Moussavi Nik, L Wilson, M Newman, K Croft, TA Mori, I Musgrave, ... Journal of Alzheimer's Disease 28 (3), 515-530, 2012 | 49 | 2012 |
Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity S Nornes, M Newman, G Verdile, S Wells, CL Stoick-Cooper, B Tucker, ... Human molecular genetics 17 (3), 402-412, 2008 | 48 | 2008 |
Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos S Nornes, M Newman, S Wells, G Verdile, RN Martins, M Lardelli Experimental cell research 315 (16), 2791-2801, 2009 | 46 | 2009 |
Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease M Newman, L Wilson, G Verdile, A Lim, I Khan, SH Moussavi Nik, ... Human molecular genetics 23 (3), 602-617, 2014 | 45 | 2014 |
The guinea pig as a model for sporadic Alzheimer’s disease (AD): the impact of cholesterol intake on expression of AD-related genes MJ Sharman, SH Moussavi Nik, MM Chen, D Ong, L Wijaya, SM Laws, ... PLoS One 8 (6), e66235, 2013 | 39 | 2013 |
Evidence for and against a pathogenic role of reduced γ-secretase activity in familial Alzheimer’s disease T Jayne, M Newman, G Verdile, G Sutherland, G Münch, I Musgrave, ... Journal of Alzheimer's Disease 52 (3), 781-799, 2016 | 37 | 2016 |
Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity SH Moussavi Nik, M Newman, L Wilson, E Ebrahimie, S Wells, I Musgrave, ... Human molecular genetics 24 (13), 3662-3678, 2015 | 35 | 2015 |
Dysregulation of neuronal iron homeostasis as an alternative unifying effect of mutations causing familial Alzheimer’s disease AL Lumsden, JT Rogers, S Majd, M Newman, GT Sutherland, G Verdile, ... Frontiers in neuroscience 12, 533, 2018 | 33 | 2018 |
Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy MA Corbett, CL van Eyk, DL Webber, SJ Bent, M Newman, K Harper, ... NPJ genomic medicine 3 (1), 1-9, 2018 | 29 | 2018 |
The response of HMGA1 to changes in oxygen availability is evolutionarily conserved SHM Nik, M Newman, M Lardelli Experimental cell research 317 (11), 1503-1512, 2011 | 29 | 2011 |
A zebrafish melanophore model of amyloidβ toxicity M Newman, L Wilson, E Camp, G Verdile, R Martins, M Lardelli Zebrafish 7 (2), 155-159, 2010 | 28 | 2010 |
Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis M Newman, B Tucker, S Nornes, A Ward, M Lardelli Journal of Alzheimer's Disease 16 (1), 133-147, 2009 | 25 | 2009 |
Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production M Newman, N Hin, S Pederson, M Lardelli Molecular brain 12 (1), 1-5, 2019 | 24 | 2019 |
Alternative splicing in a presenilin 2 variant associated with Alzheimer disease JE Braggin, SA Bucks, MM Course, CL Smith, B Sopher, L Osnis, ... Annals of clinical and translational neurology 6 (4), 762-777, 2019 | 24 | 2019 |
The zebrafish orthologue of familial Alzheimer’s disease gene PRESENILIN 2 is required for normal adult melanotic skin pigmentation H Jiang, M Newman, M Lardelli PloS one 13 (10), e0206155, 2018 | 19 | 2018 |