Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3 M Gamerdinger, P Hajieva, AM Kaya, U Wolfrum, FU Hartl, C Behl The EMBO journal 28 (7), 889-901, 2009 | 579 | 2009 |
BAG3 mediates chaperone‐based aggresome‐targeting and selective autophagy of misfolded proteins M Gamerdinger, AM Kaya, U Wolfrum, AM Clement, C Behl EMBO reports 12 (2), 149-156, 2011 | 377 | 2011 |
The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum M Gamerdinger, MA Hanebuth, T Frickey, E Deuerling Science 348 (6231), 201-207, 2015 | 144 | 2015 |
Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins M Gamerdinger, S Carra, C Behl Journal of molecular medicine 89, 1175-1182, 2011 | 126 | 2011 |
Inhibition of the myosin light chain kinase prevents hypoxia‐induced blood–brain barrier disruption CRW Kuhlmann, R Tamaki, M Gamerdinger, V Lessmann, C Behl, ... Journal of neurochemistry 102 (2), 501-507, 2007 | 92 | 2007 |
Early scanning of nascent polypeptides inside the ribosomal tunnel by NAC M Gamerdinger, K Kobayashi, A Wallisch, SG Kreft, C Sailer, R Schlömer, ... Molecular cell 75 (5), 996-1006. e8, 2019 | 81 | 2019 |
Chaperone interactions at the ribosome E Deuerling, M Gamerdinger, SG Kreft Cold Spring Harbor Perspectives in Biology 11 (11), a033977, 2019 | 76 | 2019 |
Adaptation of neuronal cells to chronic oxidative stress is associated with altered cholesterol and sphingolipid homeostasis and lysosomal function AB Clement, M Gamerdinger, IY Tamboli, D Lütjohann, J Walter, I Greeve, ... Journal of neurochemistry 111 (3), 669-682, 2009 | 59 | 2009 |
Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting A Jomaa, M Gamerdinger, HH Hsieh, A Wallisch, V Chandrasekaran, ... Science 375 (6583), 839-844, 2022 | 46 | 2022 |
Dual role of ribosome-binding domain of NAC as a potent suppressor of protein aggregation and aging-related proteinopathies K Shen, M Gamerdinger, R Chan, K Gense, EM Martin, N Sachs, ... Molecular cell 74 (4), 729-741. e7, 2019 | 43 | 2019 |
Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-β production M Gamerdinger, AB Clement, C Behl Molecular pharmacology 72 (1), 141-151, 2007 | 43 | 2007 |
A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans LA Wurmthaler, M Sack, K Gense, JS Hartig, M Gamerdinger Nature communications 10 (1), 491, 2019 | 42 | 2019 |
Oestrogen receptor subtype‐specific repression of calpain expression and calpain enzymatic activity in neuronal cells–implications for neuroprotection against Ca2+‐mediated … M Gamerdinger, D Manthey, C Behl Journal of neurochemistry 97 (1), 57-68, 2006 | 40 | 2006 |
Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins EM Martin, MP Jackson, M Gamerdinger, K Gense, TK Karamonos, ... Journal of Biological Chemistry 293 (22), 8554-8568, 2018 | 25 | 2018 |
Effects of sulindac sulfide on the membrane architecture and the activity of γ-secretase M Gamerdinger, AB Clement, C Behl Neuropharmacology 54 (6), 998-1005, 2008 | 25 | 2008 |
Protein quality control at the ribosome: focus on RAC, NAC and RQC M Gamerdinger Essays in biochemistry 60 (2), 203-212, 2016 | 22 | 2016 |
The selective β1‐adrenoceptor antagonist nebivolol is a potential oestrogen receptor agonist with neuroprotective abilities D Manthey, M Gamerdinger, C Behl British journal of pharmacology 159 (6), 1264-1273, 2010 | 19 | 2010 |
Efficient splicing-based RNA regulators for tetracycline-inducible gene expression in human cell culture and C. elegans M Finke, D Brecht, J Stifel, K Gense, M Gamerdinger, JS Hartig Nucleic Acids Research 49 (12), e71-e71, 2021 | 16 | 2021 |
Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus S Haege, D Galetzka, U Zechner, T Haaf, M Gamerdinger, C Behl, ... Neuropsychobiology 61 (4), 188-196, 2010 | 16 | 2010 |
BAG2 interferes with CHIP-mediated ubiquitination of HSP72 B Schönbühler, V Schmitt, H Huesmann, A Kern, M Gamerdinger, C Behl International journal of molecular sciences 18 (1), 69, 2016 | 13 | 2016 |