A soluble α-synuclein construct forms a dynamic tetramer W Wang, I Perovic, J Chittuluru, A Kaganovich, LTT Nguyen, J Liao, ... Proceedings of the National Academy of Sciences 108 (43), 17797-17802, 2011 | 572 | 2011 |
Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein W Wang, LTT Nguyen, C Burlak, F Chegini, F Guo, T Chataway, S Ju, ... Proceedings of the National Academy of Sciences 113 (34), 9587-9592, 2016 | 256 | 2016 |
A yeast model of FUS/TLS-dependent cytotoxicity S Ju, DF Tardiff, H Han, K Divya, Q Zhong, LE Maquat, DA Bosco, ... PLoS biology 9 (4), e1001052, 2011 | 237 | 2011 |
Polyamine pathway contributes to the pathogenesis of Parkinson disease NM Lewandowski, S Ju, M Verbitsky, B Ross, ML Geddie, E Rockenstein, ... Proceedings of the National Academy of Sciences 107 (39), 16970-16975, 2010 | 164 | 2010 |
Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 SJ Barmada, S Ju, A Arjun, A Batarse, HC Archbold, D Peisach, X Li, ... Proceedings of the National Academy of Sciences 112 (25), 7821-7826, 2015 | 138 | 2015 |
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model JW Steele, ML Lachenmayer, S Ju, A Stock, J Liken, SH Kim, LM Delgado, ... Molecular psychiatry 18 (8), 889-897, 2013 | 124 | 2013 |
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase MR Landon, RL Lieberman, QQ Hoang, S Ju, JMM Caaveiro, SD Orwig, ... Journal of computer-aided molecular design 23, 491-500, 2009 | 98 | 2009 |
Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain JW Steele, S Ju, ML Lachenmayer, J Liken, A Stock, SH Kim, LM Delgado, ... Molecular psychiatry 18 (8), 882-888, 2013 | 93 | 2013 |
Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast S Ju, G Shaltiel, A Shamir, G Agam, ML Greenberg Journal of Biological Chemistry 279 (21), 21759-21765, 2004 | 88 | 2004 |
Latrepirdine (Dimebon™) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast PR Bharadwaj, G Verdile, RK Barr, V Gupta, JW Steele, ML Lachenmayer, ... Journal of Alzheimer's disease: JAD 32 (4), 949, 2012 | 85 | 2012 |
Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis KL Jackson, RD Dayton, EA Orchard, S Ju, D Ringe, GA Petsko, ... Gene therapy 22 (1), 20-28, 2015 | 83 | 2015 |
Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis S Ju, ML Greenberg Molecular microbiology 49 (6), 1595-1604, 2003 | 53 | 2003 |
Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis Y Shi, DL Vaden, S Ju, D Ding, JH Geiger, ML Greenberg Journal of Biological Chemistry 280 (51), 41805-41810, 2005 | 50 | 2005 |
Glycogen synthase kinase‐3 is required for optimal de novo synthesis of inositol AN Azab, Q He, S Ju, G Li, ML Greenberg Molecular microbiology 63 (4), 1248-1258, 2007 | 41 | 2007 |
Epi-inositol regulates expression of the yeast INO1 gene encoding inositol-1-P synthase A Shaldubina, S Ju, DL Vaden, D Ding, RH Belmaker, ML Greenberg Molecular psychiatry 7 (2), 174-180, 2002 | 31 | 2002 |
Synthesis of cyclophospho-glucoses and glucitols EJ Amigues, ML Greenberg, S Ju, Y Chen, ME Migaud Tetrahedron 63 (40), 10042-10053, 2007 | 25 | 2007 |
1D-myo-inositol 3-phosphate synthase: conservation, regulation, and putative target of mood stabilizers S Ju, ML Greenberg Clinical Neuroscience Research 4 (3-4), 181-187, 2004 | 19 | 2004 |
A genetic screen for human genes suppressing FUS induced toxicity in yeast E Hayden, S Chen, A Chumley, C Xia, Q Zhong, S Ju G3: Genes, Genomes, Genetics 10 (6), 1843-1852, 2020 | 11 | 2020 |
Methods of reducing TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis by a UPF1 polypeptide or polynucleotide G Petsko, D Ringe, S Ju US Patent 10,533,038, 2020 | 10 | 2020 |
Supersaturated proteins in ALS E Hayden, A Cone, S Ju Proceedings of the National Academy of Sciences 114 (20), 5065-5066, 2017 | 8 | 2017 |