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Michael Lazarou
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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ...
Nature 524 (7565), 309-314, 2015
23112015
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle
Journal of Cell Biology 191 (5), 933-942, 2010
13602010
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
LA Kane, M Lazarou, AI Fogel, Y Li, K Yamano, SA Sarraf, S Banerjee, ...
Journal of Cell Biology 205 (2), 143-153, 2014
12202014
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
Science 359 (6378), eaao6047, 2018
6742018
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
M Lazarou, SM Jin, LA Kane, RJ Youle
Developmental cell 22 (2), 320-333, 2012
6732012
Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
TN Nguyen, BS Padman, J Usher, V Oorschot, G Ramm, M Lazarou
Journal of Cell Biology 215 (6), 857-874, 2016
5812016
Deciphering the molecular signals of PINK1/Parkin mitophagy
TN Nguyen, BS Padman, M Lazarou
Trends in cell biology 26 (10), 733-744, 2016
5402016
Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients
RMT McKenzie M, Lazarou M, Thorburn DR
J. Mol. Biol 361, 462-469, 2006
4792006
Analysis of the assembly profiles for mitochondrial-and nuclear-DNA-encoded subunits into complex I
M Lazarou, M McKenzie, A Ohtake, DR Thorburn, MT Ryan
Molecular and cellular biology 27 (12), 4228-4237, 2007
2932007
Bacteriophage transcytosis provides a mechanism to cross epithelial cell layers
S Nguyen, K Baker, BS Padman, R Patwa, RA Dunstan, TA Weston, ...
MBio 8 (6), 10.1128/mbio. 01874-17, 2017
2772017
Crystal structure of the mitochondrial chaperone TIM9• 10 reveals a six-bladed α-propeller
CT Webb, MA Gorman, M Lazarou, MT Ryan, JM Gulbis
Molecular cell 21 (1), 123-133, 2006
2642006
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
M Lazarou, DP Narendra, SM Jin, E Tekle, S Banerjee, RJ Youle
The Journal of Cell Biology, 2013
2472013
Parkin and mitophagy in cancer
JP Bernardini, M Lazarou, G Dewson
Oncogene 36 (10), 1315-1327, 2017
2462017
Assembly of mitochondrial complex I and defects in disease
M Lazarou, DR Thorburn, MT Ryan, M McKenzie
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (1), 78-88, 2009
2452009
Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease
CJR Dunning, M McKenzie, C Sugiana, M Lazarou, J Silke, A Connelly, ...
The EMBO journal 26 (13), 3227-3237, 2007
2342007
Structure, function, and regulation of mitofusin‐2 in health and disease
G Chandhok, M Lazarou, B Neumann
Biological Reviews 93 (2), 933-949, 2018
1982018
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
BS Padman, TN Nguyen, L Uoselis, M Skulsuppaisarn, LK Nguyen, ...
Nature communications 10 (1), 408, 2019
1842019
Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis
M McKenzie, M Lazarou, DR Thorburn, MT Ryan
Analytical biochemistry 364 (2), 128-137, 2007
1152007
Assembly of nuclear DNA‐encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria
M Lazarou, SM Smith, DR Thorburn, MT Ryan, M McKenzie
The FEBS journal 276 (22), 6701-6713, 2009
1122009
Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor
M Lazarou, D Stojanovski, AE Frazier, A Kotevski, G Dewson, WJ Craigen, ...
Journal of Biological Chemistry 285 (47), 36876-36883, 2010
1042010
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