Whole–genome characterization of chemoresistant ovarian cancer AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ... Nature 521 (7553), 489-494, 2015 | 954 | 2015 |
Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer EL Christie, S Fereday, K Doig, S Pattnaik, SJ Dawson, DDL Bowtell Journal of Clinical Oncology 35 (12), 1274-1280, 2017 | 125 | 2017 |
LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin PA Cowin, J George, S Fereday, E Loehrer, P Van Loo, C Cullinane, ... Cancer research 72 (16), 4060-4073, 2012 | 86 | 2012 |
Acquired chemotherapy resistance in ovarian cancer EL Christie, DDL Bowtell Annals of Oncology 28, viii13-viii15, 2017 | 59 | 2017 |
A community-based model of rapid autopsy in end-stage cancer patients K Alsop, H Thorne, S Sandhu, A Hamilton, C Mintoff, E Christie, O Spruyt, ... Nature biotechnology 34 (10), 1010-1014, 2016 | 48 | 2016 |
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish TA de Jong–Curtain, AC Parslow, AJ Trotter, NE Hall, H Verkade, ... Gastroenterology 136 (3), 902-911. e7, 2009 | 41 | 2009 |
Mechanisms of drug resistance in high-grade serous ovarian cancer AE Freimund, JA Beach, EL Christie, DDL Bowtell Hematology/Oncology Clinics 32 (6), 983-996, 2018 | 40 | 2018 |
Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer EL Christie, S Pattnaik, J Beach, A Copeland, N Rashoo, S Fereday, ... Nature communications 10 (1), 1-10, 2019 | 39 | 2019 |
Homologous recombination DNA repair pathway disruption and retinoblastoma protein loss are associated with exceptional survival in high-grade serous ovarian cancer DW Garsed, K Alsop, S Fereday, C Emmanuel, CJ Kennedy, ... Clinical Cancer Research 24 (3), 569-580, 2018 | 35 | 2018 |
EIF1AX and NRAS mutations co-occur and cooperate in low-grade serous ovarian carcinomas D Etemadmoghadam, WJ Azar, Y Lei, T Moujaber, DW Garsed, ... Cancer research 77 (16), 4268-4278, 2017 | 35 | 2017 |
Ovarian Carcinoma‐Associated Mesenchymal Stem Cells Arise from Tissue‐Specific Normal Stroma LG Coffman, AT Pearson, LG Frisbie, Z Freeman, E Christie, DD Bowtell, ... Stem Cells 37 (2), 257-269, 2019 | 26 | 2019 |
Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer T O’Donnell, EL Christie, A Ahuja, J Buros, BA Aksoy, DDL Bowtell, ... BMC cancer 18 (1), 1-11, 2018 | 18 | 2018 |
Pooled genomic screens identify anti-apoptotic genes as targetable mediators of chemotherapy resistance in ovarian cancer EH Stover, MB Baco, O Cohen, YY Li, EL Christie, M Bagul, A Goodale, ... Molecular Cancer Research 17 (11), 2281-2293, 2019 | 7 | 2019 |
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell, 2021 | 6 | 2021 |
Blood worth bottling: circulating tumor DNA as a cancer biomarker EL Christie, SJ Dawson, DDL Bowtell Cancer research 76 (19), 5590-5591, 2016 | 3 | 2016 |
Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models E Morrish, A Copeland, DM Moujalled, JA Powell, N Silke, A Lin, ... Blood advances 4 (20), 5062-5077, 2020 | 2 | 2020 |
Adult ischemic necrotizing enterocolitis T Mitchell, E Christie, H Syed, A Koulaouzidis, WC Tan J Coll Physicians Surg Pakistan 20 (6), 412-3, 2010 | 2 | 2010 |
Determination of mRNA and protein expression patterns in zebrafish EL Christie, AC Parslow, JK Heath Wnt Signaling, 253-272, 2008 | 1 | 2008 |
Targeting the PI3K/AKT/mTOR pathway in epithelial ovarian cancer, therapeutic treatment options for platinum-resistant ovarian cancer N Rinne, EL Christie, A Ardasheva, CH Kwok, N Demchenko, C Low, ... Cancer Drug Resistance 4, 2021 | | 2021 |
Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer A Nath, PA Cosgrove, B Copeland, H Mirsafian, EL Christie, L Pflieger, ... | | 2021 |