|ANS binding reveals common features of cytotoxic amyloid species|
B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, ...
ACS chemical biology 5 (8), 735-740, 2010
|Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms|
LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ...
Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014
|The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures|
JJ Yerbury, S Poon, S Meehan, B Thompson, JR Kumita, CM Dobson, ...
The FASEB Journal 21 (10), 2312-2322, 2007
|Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity|
MR Wilson, JJ Yerbury, S Poon
Molecular Biosystems 4 (1), 42-52, 2008
|Quality control of protein folding in extracellular space|
JJ Yerbury, EM Stewart, AR Wyatt, MR Wilson
EMBO reports 6 (12), 1131-1136, 2005
|The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin|
JJ Yerbury, MS Rybchyn, SB Easterbrook-Smith, C Henriques, MR Wilson
Biochemistry 44 (32), 10914-10925, 2005
|Walking the tightrope: Proteostasis and neurodegenerative disease.|
JJ Yerbury, L Ooi, A Dillin, DN Saunders, DM Hatters, PM Beart, ...
Journal of Neurochemistry 137 (4), 489-505, 2016
|Clusterin facilitates in vivo clearance of extracellular misfolded proteins|
AR Wyatt, JJ Yerbury, P Berghofer, I Greguric, A Katsifis, CM Dobson, ...
Cellular and Molecular Life Sciences 68 (23), 3919-3931, 2011
|CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia|
KL Williams, S Topp, S Yang, B Smith, JA Fifita, ST Warraich, KY Zhang, ...
Nature communications 7, 11253, 2016
|Protease activation of α2-macroglobulin modulates a chaperone-like action with broad specificity|
K French, JJ Yerbury, MR Wilson
Biochemistry 47 (4), 1176-1185, 2008
|α2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species|
JJ Yerbury, JR Kumita, S Meehan, CM Dobson, MR Wilson
Journal of Biological Chemistry 284 (7), 4246-4254, 2009
|The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species|
JR Kumita, S Poon, GL Caddy, CL Hagan, M Dumoulin, JJ Yerbury, ...
Journal of molecular biology 369 (1), 157-167, 2007
|Extracellular Chaperones and Proteostasis|
AR Wyatt, JJ Yerbury, H Ecroyd, MR Wilson
Annual Review of Biochemistry 82 (1), 295-322, 2013
|Clusterin interacts with Paclitaxel and confer Paclitaxel resistance in ovarian cancer|
DC Park, SG Yeo, MR Wilson, JJ Yerbury, J Kwong, WR Welch, YK Choi, ...
Neoplasia 10 (9), 964-72, 2008
|Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype|
K Roberts, R Zeineddine, L Corcoran, W Li, IL Campbell, JJ Yerbury
Glia 61 (3), 409-419, 2013
|P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia|
R Bartlett, JJ Yerbury, R Sluyter
Mediators of inflammation 2013, 271813, 2013
|Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions|
NE Farrawell, IA Lambert-Smith, ST Warraich, IP Blair, DN Saunders, ...
Scientific Reports 5, 13416, 2015
|The chaperone action of Clusterin and its putative role in quality control of extracellular protein folding|
AR Wyatt, JJ Yerbury, S Poon, R Dabbs, MR Wilson
Advances in cancer research 104, 89-114, 2009
|Structural characterization of clusterin-chaperone client protein complexes|
AR Wyatt, JJ Yerbury, MR Wilson
Journal of Biological Chemistry 284 (33), 21920-21927, 2009
|Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells|
V Sundaramoorthy, AK Walker, J Yerbury, KY Soo, MA Farg, V Hoang, ...
Cellular and molecular life sciences 70 (21), 4181-4195, 2013