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Jason Northey
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Year
PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs
S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ...
Cell metabolism 26 (5), 778-787. e5, 2017
2332017
Tissue force programs cell fate and tumor aggression
JJ Northey, L Przybyla, VM Weaver
Cancer discovery 7 (11), 1224-1237, 2017
2202017
Signaling through ShcA is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion
JJ Northey, J Chmielecki, E Ngan, C Russo, MG Annis, WJ Muller, ...
Molecular and cellular biology 28 (10), 3162-3176, 2008
982008
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
JJ Northey, AS Barrett, I Acerbi, MK Hayward, S Talamantes, IS Dean, ...
The Journal of clinical investigation 130 (11), 5721-5737, 2020
802020
Chordin-like 1 suppresses bone morphogenetic protein 4-induced breast cancer cell migration and invasion
C Cyr-Depauw, JJ Northey, S Tabariès, MG Annis, Z Dong, S Cory, ...
Molecular and Cellular Biology 36 (10), 1509-1525, 2016
612016
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells
E Ngan, JJ Northey, CM Brown, J Ursini-Siegel, PM Siegel
Journal of cell science 126 (9), 1981-1991, 2013
582013
The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility
K Roovers, S Wagner, CJ Storbeck, P O'reilly, V Lo, JJ Northey, ...
Oncogene 28 (31), 2839-2848, 2009
522009
The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer
Y He, JJ Northey, A Pelletier, Z Kos, L Meunier, B Haibe-Kains, ...
Oncogene 36 (24), 3490-3503, 2017
452017
CdGAP is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion
Y He, JJ Northey, M Primeau, RD Machado, R Trembath, PM Siegel, ...
Oncogene 30 (9), 1032-1045, 2011
412011
Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
AP Drain, N Zahir, JJ Northey, H Zhang, PJ Huang, O Maller, JN Lakins, ...
Journal of Experimental Medicine 218 (5), e20191360, 2021
382021
Tissue force programs cell fate and tumor aggression. Cancer Discov. 2017; 7: 1224–1237. doi: 10.1158/2159-8290
JJ Northey, L Przybyla, VM Weaver
CD-16-0733.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
36
Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion …
JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel
Journal of Biological Chemistry 288 (7), 5210-5222, 2013
342013
Targeting aberrant TGF-β signaling in pre-clinical models of cancer
AA Mourskaia, JJ Northey, PM Siegel
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2007
302007
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ...
Nature Biotechnology, 1-11, 2023
222023
Fighting the force: Potential of homeobox genes for tumor microenvironment regulation
JM Northcott, JJ Northey, JM Barnes, VM Weaver
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 248-253, 2015
152015
Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity
KK Tsai, SS Huang, JJ Northey, WY Liao, CC Hsu, LH Cheng, ME Werner, ...
Nature Cancer 3 (6), 734-752, 2022
142022
New horizons in advocacy engaged physical sciences and oncology research
S Samson, JJ Northey, V Plaks, C Baas, I Dean, MA LaBarge, A Goga, ...
Trends in cancer 4 (4), 260-264, 2018
82018
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells
FB Kai, G Ou, RW Tourdot, C Stashko, G Gaietta, MF Swift, N Volkmann, ...
The EMBO Journal 41 (17), e109205, 2022
72022
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
C Stashko, MK Hayward, JJ Northey, N Pearson, AJ Ironside, JN Lakins, ...
Nature communications 14 (1), 3561, 2023
52023
Mechanosensitive steroid hormone signaling and cell fate
JJ Northey, VM Weaver
Endocrinology 163 (8), bqac085, 2022
42022
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