| Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors Z Jin, X Du, Y Xu, Y Deng, M Liu, Y Zhao, B Zhang, X Li, L Zhang, C Peng, ... Nature 582 (7811), 289-293, 2020 | 3894 | 2020 |
| Structure of the RNA-dependent RNA polymerase from COVID-19 virus Y Gao, L Yan, Y Huang, F Liu, Y Zhao, L Cao, T Wang, Q Sun, Z Ming, ... Science 368 (6492), 779-782, 2020 | 1624 | 2020 |
| The catalytic mechanisms of binuclear metallohydrolases N Mitić, SJ Smith, A Neves, LW Guddat, LR Gahan, G Schenk Chemical reviews 106 (8), 3338-3363, 2006 | 481 | 2006 |
| Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase JA McCourt, SS Pang, J King-Scott, LW Guddat, RG Duggleby Proceedings of the National Academy of Sciences 103 (3), 569-573, 2006 | 450 | 2006 |
| Structural basis for RNA replication by the SARS-CoV-2 polymerase Q Wang, J Wu, H Wang, Y Gao, Q Liu, A Mu, W Ji, L Yan, Y Zhu, C Zhu, ... Cell 182 (2), 417-428. e13, 2020 | 435 | 2020 |
| Structure and mechanism of inhibition of plant acetohydroxyacid synthase RG Duggleby, JA McCourt, LW Guddat Plant Physiology and Biochemistry 46 (3), 309-324, 2008 | 404 | 2008 |
| Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur Z Jin, Y Zhao, Y Sun, B Zhang, H Wang, Y Wu, Y Zhu, C Zhu, T Hu, X Du, ... Nature structural & molecular biology 27 (6), 529-532, 2020 | 391 | 2020 |
| Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors SS Pang, RG Duggleby, LW Guddat Journal of molecular biology 317 (2), 249-262, 2002 | 267 | 2002 |
| Structure, function, and regulation of tartrate-resistant acid phosphatase GW Oddie, G Schenk, NZ Angel, N Walsh, LW Guddat, J De Jersey, ... Bone 27 (5), 575-584, 2000 | 266 | 2000 |
| Crystal structure of mammalian purple acid phosphatase LW Guddat, AS McAlpine, D Hume, S Hamilton, J de Jersey, JL Martin Structure 7 (7), 757-767, 1999 | 235 | 1999 |
| Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis L Yan, J Ge, L Zheng, Y Zhang, Y Gao, T Wang, Y Huang, Y Yang, S Gao, ... Cell 184 (1), 184-193. e10, 2021 | 230 | 2021 |
| Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase SS Pang, LW Guddat, RG Duggleby Journal of Biological Chemistry 278 (9), 7639-7644, 2003 | 230 | 2003 |
| Crystal structures of membrane transporter MmpL3, an anti-TB drug target B Zhang, J Li, X Yang, L Wu, J Zhang, Y Yang, Y Zhao, L Zhang, X Yang, ... Cell 176 (3), 636-648. e13, 2019 | 206 | 2019 |
| Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization LW Guddat, JCA Bardwell, JL Martin Structure 6 (6), 757-767, 1998 | 200 | 1998 |
| Identification of mammalian-like purple acid phosphatases in a wide range of plants G Schenk, LW Guddat, Y Ge, LE Carrington, DA Hume, S Hamilton, ... Gene 250 (1-2), 117-125, 2000 | 186 | 2000 |
| Phosphate forms an unusual tripodal complex with the Fe–Mn center of sweet potato purple acid phosphatase G Schenk, LR Gahan, LE Carrington, N Mitić, M Valizadeh, SE Hamilton, ... Proceedings of the National Academy of Sciences 102 (2), 273-278, 2005 | 169 | 2005 |
| Three-dimensional structure of a human immunoglobulin with a hinge deletion. LW Guddat, JN Herron, AB Edmundson Proceedings of the National Academy of Sciences 90 (9), 4271-4275, 1993 | 156 | 1993 |
| Binuclear metallohydrolases: complex mechanistic strategies for a simple chemical reaction G Schenk, N Mitic, LR Gahan, DL Ollis, RP McGeary, LW Guddat Accounts of Chemical Research 45 (9), 1593-1603, 2012 | 151 | 2012 |
| Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics DT Keough, D Hockova, A Holy, LMJ Naesens, TS Skinner-Adams, ... Journal of medicinal chemistry 52 (14), 4391-4399, 2009 | 149 | 2009 |
| Systematic characterization of mutations in yeast acetohydroxyacid synthase: interpretation of herbicide‐resistance data RG Duggleby, SS Pang, H Yu, LW Guddat European Journal of Biochemistry 270 (13), 2895-2904, 2003 | 139 | 2003 |
