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Johannes Pettmann
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Year
The discriminatory power of the T cell receptor
J Pettmann, A Huhn, E Abu-Shah, M Kutuzov, DB Wilson, ML Dustin, ...
bioRxiv, 2021
78*2021
Membrane ultrastructure and T cell activation
J Pettmann, AM Santos, O Dushek, SJ Davis
Frontiers in Immunology, 2152, 2018
542018
Human CD8+ T cells exhibit a shared antigen threshold for different effector responses
E Abu-Shah, N Trendel, P Kruger, J Nguyen, J Pettmann, M Kutuzov, ...
The Journal of Immunology 205 (6), 1503-1512, 2020
282020
Perfect adaptation of CD8+ T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation
N Trendel, P Kruger, S Gaglione, J Nguyen, J Pettmann, ED Sontag, ...
Science signaling 14 (666), eaay9363, 2021
272021
Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors
DO Burton J, Siller-Farfán JA, Pettmann J, Salzer B, Kutuzov M, van der Merwe PA
Proceedings of the National Academy of Sciences, 2023
212023
Mechanical forces impair antigen discrimination by reducing differences in T‐cell receptor/peptide–MHC off‐rates
J Pettmann, L Awada, B Różycki, A Huhn, S Faour, M Kutuzov, L Limozin, ...
The EMBO Journal 42 (7), e111841, 2023
172023
Quantitative contributions of TNF receptor superfamily members to CD8+ T‐cell responses
J Nguyen, J Pettmann, P Kruger, O Dushek
Molecular Systems Biology 17 (11), e10560, 2021
8*2021
T cell microvilli simulations show operation near packing limit and impact on antigen recognition
J Morgan, J Pettmann, O Dushek, AE Lindsay
Biophysical Journal 121 (21), 4128-4136, 2022
32022
Using CombiCells, a platform enabling titration and combinatorial display of cell surface ligands, to investigate the sensitivity and costimulatory requirements of TCRs and CARs
A Patel, V Andre, S Bustamante Eguiguren, MI Barton, EM Denham, ...
bioRxiv, 2023.06. 15.545075, 2023
22023
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors
A Patel, V Andre, SB Eguiguren, MI Barton, J Burton, EM Denham, ...
The EMBO Journal, 1-19, 2023
12023
Mechanical forces impair antigen discrimination by reducing differences in T cell receptor off-rates
J Pettmann, L Awada, B Różycki, A Huhn, S Faour, M Kutuzov, L Limozin, ...
bioRxiv, 2022.05. 05.490751, 2022
12022
Antigen discrimination in primary human T cells
J Pettmann
University of Oxford, 2021
2021
Stochastic Simulation of Close-Contact Dynamics in Immune Recognition
JM Morgan, A Lindsay, O Dushek, J Pettmann
Biophysical Journal 118 (3), 305a, 2020
2020
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Articles 1–13