Patrick Humbert
Patrick Humbert
Professor of Cancer Biology, Department of Biochemistry and Genetics, La Trobe University
Verified email at - Homepage
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E2f3 is critical for normal cellular proliferation
PO Humbert, R Verona, JM Trimarchi, C Rogers, S Dandapani, JA Lees
Genes & development 14 (6), 690-703, 2000
Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
P Humbert, S Russell, H Richardson
Bioessays 25 (6), 542-553, 2003
Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module
PO Humbert, NA Grzeschik, AM Brumby, R Galea, I Elsum, ...
Oncogene 27 (55), 6888-6907, 2008
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation
MJ Ludford-Menting, J Oliaro, F Sacirbegovic, ETY Cheah, N Pedersen, ...
Immunity 22 (6), 737-748, 2005
E2F4 is essential for normal erythrocyte maturation and neonatal viability
PO Humbert, C Rogers, S Ganiatsas, RL Landsberg, JM Trimarchi, ...
Molecular cell 6 (2), 281-291, 2000
Epidermal wound repair is regulated by the planar cell polarity signaling pathway
J Caddy, T Wilanowski, C Darido, S Dworkin, SB Ting, Q Zhao, G Rank, ...
Developmental cell 19 (1), 138-147, 2010
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia
HB Pearson, PA Perez-Mancera, LE Dow, A Ryan, P Tennstedt, D Bogani, ...
The Journal of clinical investigation 121 (11), 4257-4267, 2011
The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge
LE Dow, JS Kauffman, J Caddy, AS Peterson, SM Jane, SM Russell, ...
Oncogene 26 (16), 2272-2282, 2007
Multiscale modeling of form and function
AJ Engler, PO Humbert, B Wehrle-Haller, VM Weaver
Science 324 (5924), 208-212, 2009
The Scribble and Par complexes in polarity and migration: friends or foes?
PO Humbert, LE Dow, SM Russell
Trends in cell biology 16 (12), 622-630, 2006
Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling
LE Dow, IA Elsum, CL King, KM Kinross, HE Richardson, PO Humbert
Oncogene 27 (46), 5988-6001, 2008
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery
LF Willoughby, T Schlosser, SA Manning, JP Parisot, IP Street, ...
Disease models & mechanisms 6 (2), 521-529, 2013
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms
J Oliaro, V Van Ham, F Sacirbegovic, A Pasam, Z Bomzon, K Pham, ...
The Journal of Immunology 185 (1), 367-375, 2010
Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis
LE Dow, PO Humbert
International review of cytology 262, 253-302, 2007
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble
LE Dow, AM Brumby, R Muratore, ML Coombe, KA Sedelies, JA Trapani, ...
Oncogene 22 (58), 9225-9230, 2003
The Scribble–Dlg–Lgl polarity module in development and cancer: from flies to man
I Elsum, L Yates, PO Humbert, HE Richardson
Essays in biochemistry 53, 141-168, 2012
The scribble cell polarity module in the regulation of cell signaling in tissue development and tumorigenesis
R Stephens, K Lim, M Portela, M Kvansakul, PO Humbert, HE Richardson
Journal of molecular biology 430 (19), 3585-3612, 2018
Increasing intracellular bioavailable copper selectively targets prostate cancer cells
MA Cater, HB Pearson, K Wolyniec, P Klaver, M Bilandzic, BM Paterson, ...
ACS chemical biology 8 (7), 1621-1631, 2013
Intermittent hypoxia induces a metastatic phenotype in breast cancer
A Chen, J Sceneay, N Gödde, T Kinwel, S Ham, EW Thompson, ...
Oncogene 37 (31), 4214-4225, 2018
Scribble interacts with β-catenin to localize synaptic vesicles to synapses
Y Sun, M Aiga, E Yoshida, PO Humbert, SX Bamji
Molecular biology of the cell 20 (14), 3390-3400, 2009
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