|E2f3 is critical for normal cellular proliferation|
PO Humbert, R Verona, JM Trimarchi, C Rogers, S Dandapani, JA Lees
Genes & development 14 (6), 690-703, 2000
|Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer|
P Humbert, S Russell, H Richardson
Bioessays 25 (6), 542-553, 2003
|Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module|
PO Humbert, NA Grzeschik, AM Brumby, R Galea, I Elsum, ...
Oncogene 27 (55), 6888-6907, 2008
|A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation|
MJ Ludford-Menting, J Oliaro, F Sacirbegovic, ETY Cheah, N Pedersen, ...
Immunity 22 (6), 737-748, 2005
|E2F4 is essential for normal erythrocyte maturation and neonatal viability|
PO Humbert, C Rogers, S Ganiatsas, RL Landsberg, JM Trimarchi, ...
Molecular cell 6 (2), 281-291, 2000
|The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge|
LE Dow, JS Kauffman, J Caddy, AS Peterson, SM Jane, SM Russell, ...
Oncogene 26 (16), 2272-2282, 2007
|Epidermal wound repair is regulated by the planar cell polarity signaling pathway|
J Caddy, T Wilanowski, C Darido, S Dworkin, SB Ting, Q Zhao, G Rank, ...
Developmental cell 19 (1), 138-147, 2010
|Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling|
LE Dow, IA Elsum, CL King, KM Kinross, HE Richardson, PO Humbert
Oncogene 27 (46), 5988-6001, 2008
|SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia|
HB Pearson, PA Perez-Mancera, LE Dow, A Ryan, P Tennstedt, D Bogani, ...
The Journal of clinical investigation 121 (11), 4257-4267, 2011
|The Scribble and Par complexes in polarity and migration: friends or foes?|
PO Humbert, LE Dow, SM Russell
Trends in cell biology 16 (12), 622-630, 2006
|Multiscale modeling of form and function|
AJ Engler, PO Humbert, B Wehrle-Haller, VM Weaver
Science 324 (5924), 208-212, 2009
|hScrib is a functional homologue of the Drosophila tumour suppressor Scribble|
LE Dow, AM Brumby, R Muratore, ML Coombe, KA Sedelies, JA Trapani, ...
Oncogene 22 (58), 9225-9230, 2003
|Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis|
LE Dow, PO Humbert
International review of cytology 262, 253-302, 2007
|Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms|
J Oliaro, V Van Ham, F Sacirbegovic, A Pasam, Z Bomzon, K Pham, ...
The Journal of Immunology 185 (1), 367-375, 2010
|An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery|
LF Willoughby, T Schlosser, SA Manning, JP Parisot, IP Street, ...
Disease models & mechanisms 6 (2), 521-529, 2013
|The Scribble–Dlg–Lgl polarity module in development and cancer: from flies to man|
AD Chalmers, P Whitley, I Elsum, L Yates, PO Humbert, HE Richardson
Essays in biochemistry 53, 141-168, 2012
|Scribble interacts with β-catenin to localize synaptic vesicles to synapses|
Y Sun, M Aiga, E Yoshida, PO Humbert, SX Bamji
Molecular biology of the cell 20 (14), 3390-3400, 2009
|Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions|
NJ Godde, RC Galea, IA Elsum, PO Humbert
Journal of mammary gland biology and neoplasia 15 (2), 149-168, 2010
|Increasing intracellular bioavailable copper selectively targets prostate cancer cells|
MA Cater, HB Pearson, K Wolyniec, P Klaver, M Bilandzic, BM Paterson, ...
ACS chemical biology 8 (7), 1621-1631, 2013
|Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis|
AM Brumby, KR Goulding, T Schlosser, S Loi, R Galea, P Khoo, ...
Genetics 188 (1), 105-125, 2011