Alex Avdeef
Alex Avdeef
Consultant, in-ADME Research
Verified email at in-adme.com - Homepage
Title
Cited by
Cited by
Year
Absorption and drug development: solubility, permeability, and charge state
A Avdeef
John Wiley & Sons, 2012
8672012
Physicochemical profiling (solubility, permeability and charge state)
A Avdeef
Current topics in medicinal chemistry 1 (4), 277-351, 2001
6452001
Coexistence of passive and carrier-mediated processes in drug transport
K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ...
Nature reviews Drug discovery 9 (8), 597-614, 2010
4912010
pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of lonizable drugs
A Avdeef, KJ Box, JEA Comer, C Hibbert, KY Tam
Pharmaceutical research 15 (2), 209-215, 1998
4511998
Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin
A Avdeef, SR Sofen, TL Bregante, KN Raymond
Journal of the American Chemical Society 100 (17), 5362-5370, 1978
3761978
Coordination chemistry of microbial iron transport compounds. 19. Stability constants and electrochemical behavior of ferric enterobactin and model complexes
WR Harris, CJ Carrano, SR Cooper, SR Sofen, AE Avdeef, JV McArdle, ...
Journal of the American Chemical Society 101 (20), 6097-6104, 1979
3401979
pH-metric solubility. 2: correlation between the acid-base titration and the saturation shake-flask solubility-pH methods
A Avdeef, CM Berger, C Brownell
Pharmaceutical research 17 (1), 85-89, 2000
2972000
Absorption classification of oral drugs based on molecular surface properties
CAS Bergström, M Strafford, L Lazorova, A Avdeef, K Luthman, ...
Journal of medicinal chemistry 46 (4), 558-570, 2003
2962003
PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures
A Avdeef, KJ Box, JEA Comer, M Gilges, M Hadley, C Hibbert, ...
Journal of pharmaceutical and biomedical analysis 20 (4), 631-641, 1999
2681999
Solubility of sparingly-soluble ionizable drugs
A Avdeef
Advanced drug delivery reviews 59 (7), 568-590, 2007
2662007
pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances
A Avdeef, JEA Comer, SJ Thomson
Analytical Chemistry 65 (1), 42-49, 1993
2621993
pH-metric log P. II: Refinement of partition coefficients and ionization constants of multiprotic substances
A Avdeef
Journal of pharmaceutical sciences 82 (2), 183-190, 1993
2551993
Classification analysis of P-glycoprotein substrate specificity
R Didziapetris, P Japertas, A Avdeef, A Petrauskas
Journal of drug targeting 11 (7), 391-406, 2003
2462003
Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds
R Yumoto, T Murakami, Y Nakamoto, R Hasegawa, J Nagai, M Takano
Journal of Pharmacology and Experimental Therapeutics 289 (1), 149-155, 1999
2231999
PAMPA—critical factors for better predictions of absorption
A Avdeef, S Bendels, L Di, B Faller, M Kansy, K Sugano, Y Yamauchi
Journal of pharmaceutical sciences 96 (11), 2893-2909, 2007
2132007
PH‐metric log P. Part 1. Difference plots for determining ion‐pair octanol‐water partition coefficients of multiprotic substances
A Avdeef
Quantitative Structure‐Activity Relationships 11 (4), 510-517, 1992
2031992
PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones
M Bermejo, A Avdeef, A Ruiz, R Nalda, JA Ruell, O Tsinman, I González, ...
European Journal of Pharmaceutical Sciences 21 (4), 429-441, 2004
1932004
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method
A Avdeef, P Artursson, S Neuhoff, L Lazorova, J Gråsjö, S Tavelin
European journal of pharmaceutical sciences 24 (4), 333-349, 2005
1892005
In vitro trans-monolayer permeability calculations: often forgotten assumptions
KA Youdim, A Avdeef, NJ Abbott
Drug discovery today 8 (21), 997-1003, 2003
1782003
Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques
A Avdeef, B Testa
Cellular and Molecular Life Sciences CMLS 59 (10), 1681-1689, 2002
1762002
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