A central role for venom in predation by Varanus komodoensis (Komodo Dragon) and the extinct giant Varanus (Megalania) priscus BG Fry, S Wroe, W Teeuwisse, MJP van Osch, K Moreno, J Ingle, ... Proceedings of the National Academy of Sciences 106 (22), 8969-8974, 2009 | 166 | 2009 |
Versatile New Bis(thiosemicarbazone) Bifunctional Chelators: Synthesis, Conjugation to Bombesin(7−14)-NH2, and Copper-64 Radiolabeling BM Paterson, JA Karas, DB Scanlon, JM White, PS Donnelly Inorganic chemistry 49 (4), 1884-1893, 2010 | 100 | 2010 |
Functional and structural diversification of the Anguimorpha lizard venom system BG Fry, K Winter, JA Norman, K Roelants, RJA Nabuurs, MJP Van Osch, ... Molecular & Cellular Proteomics 9 (11), 2369-2390, 2010 | 94 | 2010 |
The antimicrobial activity of cannabinoids JA Karas, LJM Wong, OKA Paulin, AC Mazeh, MH Hussein, J Li, T Velkov Antibiotics 9 (7), 406, 2020 | 87 | 2020 |
Novel Venom Proteins Produced by Differential Domain-Expression Strategies in Beaded Lizards and Gila Monsters (genus Heloderma) BG Fry, K Roelants, K Winter, WC Hodgson, L Griesman, HF Kwok, ... Molecular Biology and Evolution 27 (2), 395-407, 2010 | 87 | 2010 |
Rapid optimization of a peptide inhibitor of malaria parasite invasion by comprehensive N-methyl scanning KS Harris, JL Casey, AM Coley, JA Karas, JK Sabo, YY Tan, O Dolezal, ... Journal of Biological Chemistry 284 (14), 9361-9371, 2009 | 77 | 2009 |
Macrobicyclic Cage Amine Ligands for Copper Radiopharmaceuticals: A Single Bivalent Cage Amine Containing Two Lys3-bombesin Targeting Peptides MT Ma, MS Cooper, RL Paul, KP Shaw, JA Karas, D Scanlon, JM White, ... Inorganic Chemistry 50 (14), 6701-6710, 2011 | 64 | 2011 |
Gallium-68 complex of a macrobicyclic cage amine chelator tethered to two integrin-targeting peptides for diagnostic tumor imaging MT Ma, OC Neels, D Denoyer, P Roselt, JA Karas, DB Scanlon, JM White, ... Bioconjugate chemistry 22 (10), 2093-2103, 2011 | 60 | 2011 |
2‐Nitroveratryl as a photocleavable thiol‐protecting group for directed disulfide bond formation in the chemical synthesis of insulin JA Karas, DB Scanlon, BE Forbes, I Vetter, RJ Lewis, J Gardiner, ... Chemistry–A European Journal 20 (31), 9549-9552, 2014 | 58 | 2014 |
Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers WM Kok, JM Cottam, GD Ciccotosto, LA Miles, JA Karas, DB Scanlon, ... Chemical Science 4 (12), 4449-4454, 2013 | 55 | 2013 |
A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides MT Ma, JA Karas, JM White, D Scanlon, PS Donnelly Chemical Communications, 3237-3239, 2009 | 46 | 2009 |
Structure–activity relationships of daptomycin lipopeptides JA Karas, GP Carter, BP Howden, AM Turner, OKA Paulin, JD Swarbrick, ... Journal of medicinal chemistry 63 (22), 13266-13290, 2020 | 45 | 2020 |
Total chemical synthesis of a nonfibrillating human glycoinsulin MA Hossain, R Okamoto, JA Karas, P Praveen, M Liu, BE Forbes, ... Journal of the American Chemical Society 142 (3), 1164-1169, 2019 | 44 | 2019 |
Total chemical synthesis of an intra‐A‐chain cystathionine human insulin analogue with enhanced thermal stability JA Karas, NA Patil, J Tailhades, MA Sani, DB Scanlon, BE Forbes, ... Angewandte Chemie 128 (47), 14963-14967, 2016 | 44 | 2016 |
Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails H Safavi-Hemami, DG Gorasia, AM Steiner, NA Williamson, JA Karas, ... Journal of Biological Chemistry 287 (41), 34288-34303, 2012 | 42 | 2012 |
The chemical synthesis of insulin: an enduring challenge JA Karas, JD Wade, MA Hossain Chemical reviews 121 (8), 4531-4560, 2021 | 40 | 2021 |
Synthesis and structure− activity relationships of teixobactin JA Karas, F Chen, EK Schneider‐Futschik, Z Kang, M Hussein, ... Annals of the New York Academy of Sciences 1459 (1), 86-105, 2020 | 37 | 2020 |
Embryonic toxin expression in the cone snail Conus victoriae: primed to kill or divergent function? H Safavi-Hemami, WA Siero, Z Kuang, NA Williamson, JA Karas, LR Page, ... Journal of Biological Chemistry 286 (25), 22546-22557, 2011 | 36 | 2011 |
The killing mechanism of teixobactin against methicillin-resistant Staphylococcus aureus: an untargeted metabolomics study M Hussein, JA Karas, EK Schneider-Futschik, F Chen, J Swarbrick, ... Msystems 5 (3), 10.1128/msystems. 00077-20, 2020 | 33 | 2020 |
Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid β peptide WM Kok, DB Scanlon, JA Karas, LA Miles, DJ Tew, MW Parker, ... Chemical Communications, 6228-6230, 2009 | 33 | 2009 |