| An overview of the serpin superfamily RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ... Genome biology 7, 1-11, 2006 | 907 | 2006 |
| GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop G Fenalti, RHP Law, AM Buckle, C Langendorf, K Tuck, CJ Rosado, ... Nature structural & molecular biology 14 (4), 280-286, 2007 | 267 | 2007 |
| Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling JW Scott, N Ling, SMA Issa, TA Dite, MT O’Brien, ZP Chen, S Galic, ... Chemistry & biology 21 (5), 619-627, 2014 | 171 | 2014 |
| mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress NXY Ling, A Kaczmarek, A Hoque, E Davie, KRW Ngoei, KR Morrison, ... Nature metabolism 2 (1), 41-49, 2020 | 146 | 2020 |
| AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 TA Dite, CG Langendorf, A Hoque, S Galic, RJ Rebello, AJ Ovens, ... Journal of Biological Chemistry 293 (23), 8874-8885, 2018 | 128 | 2018 |
| Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms SL Pinkosky, JW Scott, EM Desjardins, BK Smith, EA Day, RJ Ford, ... Nature metabolism 2 (9), 873-881, 2020 | 112 | 2020 |
| Choreography of AMPK activation CG Langendorf, BE Kemp Cell research 25 (1), 5-6, 2015 | 81 | 2015 |
| The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs TA Dite, NXY Ling, JW Scott, A Hoque, S Galic, BL Parker, KRW Ngoei, ... Nature Communications 8 (1), 571, 2017 | 80 | 2017 |
| Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding CG Langendorf, KRW Ngoei, JW Scott, NXY Ling, SMA Issa, MA Gorman, ... Nature communications 7 (1), 10912, 2016 | 78 | 2016 |
| Inhibition of AMP-activated protein kinase at the allosteric drug-binding site promotes islet insulin release JW Scott, S Galic, KL Graham, R Foitzik, NXY Ling, TA Dite, SMA Issa, ... Chemistry & biology 22 (6), 705-711, 2015 | 61 | 2015 |
| New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology AA Rosdah, WJ Smiles, JS Oakhill, JW Scott, CG Langendorf, ... Pharmacology & therapeutics 213, 107594, 2020 | 53 | 2020 |
| Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4 KRW Ngoei, CG Langendorf, NXY Ling, A Hoque, S Varghese, ... Cell chemical biology 25 (6), 728-737. e9, 2018 | 51 | 2018 |
| X-ray crystal structure of the fibrinolysis inhibitor α2-antiplasmin RHP Law, T Sofian, WT Kan, AJ Horvath, CR Hitchen, CG Langendorf, ... Blood, The Journal of the American Society of Hematology 111 (4), 2049-2052, 2008 | 47 | 2008 |
| Structural mechanisms of inactivation in scabies mite serine protease paralogues K Fischer, CG Langendorf, JA Irving, S Reynolds, C Willis, S Beckham, ... Journal of molecular biology 390 (4), 635-645, 2009 | 44 | 2009 |
| The X-Ray Crystal Structure of Escherichia coli Succinic Semialdehyde Dehydrogenase; Structural Insights into NADP+/Enzyme Interactions CG Langendorf, TLG Key, G Fenalti, WT Kan, AM Buckle, ... PLoS One 5 (2), e9280, 2010 | 41 | 2010 |
| Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder JW Scott, E Park, RM Rodriguiz, JS Oakhill, SMA Issa, MT O’Brien, ... Scientific reports 5 (1), 14436, 2015 | 40 | 2015 |
| An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes B Jayakrishnan, DE Hoke, CG Langendorf, AM Buckle, MJ Rowley PLoS One 6 (4), e18411, 2011 | 39 | 2011 |
| CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins CG Langendorf, MT O'Brien, KRW Ngoei, LM McAloon, U Dhagat, ... Journal of Biological Chemistry 295 (48), 16239-16250, 2020 | 36 | 2020 |
| In depth analysis of kinase cross screening data to identify CAMKK2 inhibitory scaffolds SN O’Byrne, JW Scott, JR Pilotte, AS Santiago, CG Langendorf, JS Oakhill, ... Molecules 25 (2), 325, 2020 | 32 | 2020 |
| Structure of granzyme C reveals an unusual mechanism of protease autoinhibition D Kaiserman, AM Buckle, P Van Damme, JA Irving, RHP Law, ... Proceedings of the National Academy of Sciences 106 (14), 5587-5592, 2009 | 31 | 2009 |
