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Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2 M Rolland, PT Edlefsen, BB Larsen, S Tovanabutra, E Sanders-Buell, ... Nature 490 (7420), 417-420, 2012 | 489 | 2012 |
Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen JG Jardine, T Ota, D Sok, M Pauthner, DW Kulp, O Kalyuzhniy, PD Skog, ... Science 349 (6244), 156-161, 2015 | 426 | 2015 |
HIV vaccine design to target germline precursors of glycan-dependent broadly neutralizing antibodies JM Steichen, DW Kulp, T Tokatlian, A Escolano, P Dosenovic, ... Immunity 45 (3), 483-496, 2016 | 370 | 2016 |
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies AT McGuire, S Hoot, AM Dreyer, A Lippy, A Stuart, KW Cohen, J Jardine, ... Journal of Experimental Medicine 210 (4), 655-663, 2013 | 349 | 2013 |
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ... Cell 177 (5), 1153-1171. e28, 2019 | 308 | 2019 |
Precursor frequency and affinity determine B cell competitive fitness in germinal centers, tested with germline-targeting HIV vaccine immunogens RK Abbott, JH Lee, S Menis, P Skog, M Rossi, T Ota, DW Kulp, D Bhullar, ... Immunity 48 (1), 133-146. e6, 2018 | 303 | 2018 |
Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies B Briney, D Sok, JG Jardine, DW Kulp, P Skog, S Menis, R Jacak, ... Cell 166 (6), 1459-1470. e11, 2016 | 258 | 2016 |
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers T Tokatlian, BJ Read, CA Jones, DW Kulp, S Menis, JYH Chang, ... Science 363 (6427), 649-654, 2019 | 247 | 2019 |
Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies LE McCoy, MJ van Gils, G Ozorowski, T Messmer, B Briney, JE Voss, ... Cell reports 16 (9), 2327-2338, 2016 | 233 | 2016 |
Global site-specific N-glycosylation analysis of HIV envelope glycoprotein L Cao, JK Diedrich, DW Kulp, M Pauthner, L He, SKR Park, D Sok, CY Su, ... Nature communications 8 (1), 14954, 2017 | 227 | 2017 |
Induction of HIV neutralizing antibody lineages in mice with diverse precursor repertoires M Tian, C Cheng, X Chen, H Duan, HL Cheng, M Dao, Z Sheng, M Kimble, ... Cell 166 (6), 1471-1484. e18, 2016 | 222 | 2016 |
Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV D Sok, KJ Doores, B Briney, KM Le, KL Saye-Francisco, A Ramos, ... Science translational medicine 6 (236), 236ra63-236ra63, 2014 | 208 | 2014 |
Engineered immunogen binding to alum adjuvant enhances humoral immunity TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ... Nature Medicine 26 (3), 430-440, 2020 | 202 | 2020 |
Vaccine-elicited tier 2 HIV-1 neutralizing antibodies bind to quaternary epitopes involving glycan-deficient patches proximal to the CD4 binding site ET Crooks, T Tong, B Chakrabarti, K Narayan, IS Georgiev, S Menis, ... PLoS pathogens 11 (5), e1004932, 2015 | 169 | 2015 |
Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice D Sok, B Briney, JG Jardine, DW Kulp, S Menis, M Pauthner, A Wood, ... Science 353 (6307), 1557-1560, 2016 | 167 | 2016 |
Enhancing humoral immunity via sustained-release implantable microneedle patch vaccination AV Boopathy, A Mandal, DW Kulp, S Menis, NR Bennett, HC Watkins, ... Proceedings of the National Academy of Sciences 116 (33), 16473-16478, 2019 | 162 | 2019 |
Multifaceted effects of antigen valency on B cell response composition and differentiation in vivo Y Kato, RK Abbott, BL Freeman, S Haupt, B Groschel, M Silva, S Menis, ... Immunity 53 (3), 548-563. e8, 2020 | 161 | 2020 |
Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies LK Pritchard, DIR Spencer, L Royle, C Bonomelli, GE Seabright, ... Nature communications 6 (1), 7479, 2015 | 142 | 2015 |
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer L Cao, M Pauthner, R Andrabi, K Rantalainen, Z Berndsen, JK Diedrich, ... Nature communications 9 (1), 3693, 2018 | 127 | 2018 |