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Niall D Geoghegan
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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
Science 359 (6378), eaao6047, 2018
6862018
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ...
Nature communications 11 (1), 3151, 2020
2172020
Flexible usage and interconnectivity of diverse cell death pathways protect against intracellular infection
M Doerflinger, Y Deng, P Whitney, R Salvamoser, S Engel, AJ Kueh, L Tai, ...
Immunity 53 (3), 533-547. e7, 2020
1102020
Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors
MR Dent, I López-Duarte, CJ Dickson, ND Geoghegan, JM Cooper, ...
Physical Chemistry Chemical Physics 17 (28), 18393-18402, 2015
1072015
Activation mechanism of PINK1
ZY Gan, S Callegari, SA Cobbold, TR Cotton, MJ Mlodzianoski, ...
Nature 602 (7896), 328-335, 2022
812022
Smchd1 targeting to the inactive X is dependent on the Xist-HnrnpK-PRC1 pathway
N Jansz, T Nesterova, A Keniry, M Iminitoff, PF Hickey, G Pintacuda, ...
Cell reports 25 (7), 1912-1923. e9, 2018
662018
4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation
ND Geoghegan, C Evelyn, LW Whitehead, M Pasternak, P McDonald, ...
Nature communications 12 (1), 3620, 2021
332021
PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum
SW Scally, T Triglia, C Evelyn, BA Seager, M Pasternak, PS Lim, J Healer, ...
Nature microbiology 7 (12), 2039-2053, 2022
292022
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24
S Davidson, CH Yu, A Steiner, F Ebstein, PJ Baker, V Jarur-Chamy, ...
Science Immunology 7 (68), eabi6763, 2022
282022
The reinvention of twentieth century microscopy for three‐dimensional imaging
LW Whitehead, K McArthur, ND Geoghegan, KL Rogers
Immunology and Cell Biology 95 (6), 520-524, 2017
272017
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science 359, eaao6047
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
262018
Alectinib induces marked red cell spheroacanthocytosis in a near-ubiquitous fashion and is associated with reduced eosin-5-maleimide binding
JA Kuzich, S Heynemann, N Geoghegan, C Evelyn, S O'Mahoney, ...
Pathology 53 (5), 608-612, 2021
152021
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes
S Morris, ND Geoghegan, JBA Sadler, AM Koester, HL Black, M Laub, ...
PeerJ 8, e8751, 2020
132020
Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission
S Lopaticki, R McConville, A John, N Geoghegan, SD Mohamed, ...
Nature communications 13 (1), 4400, 2022
112022
Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo
A Hawdon, ND Geoghegan, M Mohenska, A Elsenhans, C Ferguson, ...
Nature Communications 14 (1), 2909, 2023
72023
RhopH2 and RhopH3 export enables assembly of the RhopH complex on P. falciparum-infected erythrocyte membranes
M Pasternak, JMJ Verhoef, W Wong, T Triglia, MJ Mlodzianoski, ...
Communications Biology 5 (1), 333, 2022
42022
Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics
MG Dans, H Piirainen, W Nguyen, S Khurana, S Mehra, Z Razook, ...
PLoS Biology 21 (4), e3002066, 2023
22023
Aryl amino acetamides prevent the development of Plasmodium falciparum rings via inhibition of the lipid transfer protein PfSTART1
MG Dans, C Boulet, GM Watson, W Nguyen, JM Dziekan, C Evelyn, ...
bioRxiv, 2023.11. 02.565411, 2023
12023
Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion
LY Liang, ND Geoghegan, M Mlodzianoski, A Leis, LW Whitehead, ...
Communications Biology 7 (1), 461, 2024
2024
Increasing histone acetylation improves sociability and restores learning and memory in KAT6B-haploinsufficient mice
MI Bergamasco, HK Vanyai, AL Garnham, ND Geoghegan, AP Vogel, ...
The Journal of Clinical Investigation 134 (7), 2024
2024
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