| Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies W Li, H Zhang, YG Assaraf, K Zhao, X Xu, J Xie, DH Yang, ZS Chen Drug Resistance Updates 27, 14-29, 2016 | 648 | 2016 |
| Modulating ROS to overcome multidrug resistance in cancer Q Cui, JQ Wang, YG Assaraf, L Ren, P Gupta, L Wei, CR Ashby Jr, ... Drug Resistance Updates 41, 1-25, 2018 | 471 | 2018 |
| Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse DH Yang, EG Moss Gene Expression Patterns 3 (6), 719-726, 2003 | 240 | 2003 |
| Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis DH Yang, ER Smith, IH Roland, Z Sheng, J He, WD Martin, TC Hamilton, ... Developmental biology 251 (1), 27-44, 2002 | 191 | 2002 |
| Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis AE Kudinov, A Deneka, AS Nikonova, TN Beck, YH Ahn, X Liu, ... Proceedings of the National Academy of Sciences 113 (25), 6955-6960, 2016 | 131 | 2016 |
| Enhanced chemosensitization in multidrug-resistant human breast cancer cells by inhibition of IL-6 and IL-8 production Z Shi, WM Yang, LP Chen, DH Yang, Q Zhou, J Zhu, JJ Chen, RC Huang, ... Breast cancer research and treatment 135, 737-747, 2012 | 129 | 2012 |
| p16 status, pathologic and clinical characteristics, biomolecular signature, and long‐term outcomes in head and neck squamous cell carcinomas of unknown primary LM Keller, TJ Galloway, T Holdbrook, K Ruth, D Yang, C Dubyk, D Flieder, ... Head & neck 36 (12), 1677-1684, 2014 | 127 | 2014 |
| Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis KQ Cai, CD Capo‐Chichi, ME Rula, DH Yang, XX Xu Developmental Dynamics 237 (10), 2820-2829, 2008 | 112 | 2008 |
| Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters YF Fan, W Zhang, L Zeng, ZN Lei, CY Cai, P Gupta, DH Yang, Q Cui, ... Cancer letters 421, 186-198, 2018 | 107 | 2018 |
| Discovery of novel quinoline–chalcone derivatives as potent antitumor agents with microtubule polymerization inhibitory activity W Li, F Xu, W Shuai, H Sun, H Yao, C Ma, S Xu, H Yao, Z Zhu, DH Yang, ... Journal of medicinal chemistry 62 (2), 993-1013, 2018 | 103 | 2018 |
| A novel potent anticancer compound optimized from a natural oridonin scaffold induces apoptosis and cell cycle arrest through the mitochondrial pathway S Xu, H Yao, S Luo, YK Zhang, DH Yang, D Li, G Wang, M Hu, Y Qiu, ... Journal of Medicinal Chemistry 60 (4), 1449-1468, 2017 | 92 | 2017 |
| The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter PR Ding, AK Tiwari, S Ohnuma, JWKK Lee, X An, CL Dai, QS Lu, S Singh, ... PloS one 6 (4), e19329, 2011 | 92 | 2011 |
| Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies IH Roland, WL Yang, DH Yang, MB Daly, RF Ozols, TC Hamilton, ... Cancer 98 (12), 2607-2623, 2003 | 90 | 2003 |
| Disabled-2 is an epithelial surface positioning gene DH Yang, KQ Cai, IH Roland, ER Smith, XX Xu Journal of biological chemistry 282 (17), 13114-13122, 2007 | 89 | 2007 |
| Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity DH Yang, ER Smith, C Cohen, H Wu, C Patriotis, AK Godwin, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2002 | 87 | 2002 |
| Endogenous sterol metabolites regulate growth of EGFR/KRAS-dependent tumors via LXR L Gabitova, D Restifo, A Gorin, K Manocha, E Handorf, DH Yang, KQ Cai, ... Cell reports 12 (11), 1927-1938, 2015 | 85 | 2015 |
| Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis CD Capo‐Chichi, ER Smith, DH Yang, IH Roland, L Vanderveer, ... Cancer 95 (8), 1802-1815, 2002 | 83 | 2002 |
| β1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity X Zhang, G Mernaugh, DH Yang, L Gewin, MB Srichai, RC Harris, ... Development 136 (19), 3357-3366, 2009 | 81 | 2009 |
| Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 ZN Lei, ZX Wu, S Dong, DH Yang, L Zhang, Z Ke, C Zou, ZS Chen Pharmacology & Therapeutics 216, 107672, 2020 | 80 | 2020 |
| Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation A Sukhanova, A Gorin, IG Serebriiskii, L Gabitova, H Zheng, D Restifo, ... Cancer discovery 3 (1), 96-111, 2013 | 79 | 2013 |
