| Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the spike S1 receptor-binding domain with heparin CJ Mycroft-West, D Su, I Pagani, TR Rudd, S Elli, NS Gandhi, ... Thrombosis and haemostasis 120 (12), 1700-1715, 2020 | 315 | 2020 |
| PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models K Dredge, E Hammond, P Handley, TJ Gonda, MT Smith, C Vincent, ... British journal of cancer 104 (4), 635-642, 2011 | 204 | 2011 |
| PI-88 and novel heparan sulfate mimetics inhibit angiogenesis V Ferro, K Dredge, L Liu, E Hammond, I Bytheway, C Li, K Johnstone, ... Seminars in thrombosis and hemostasis 33 (05), 557-568, 2007 | 191 | 2007 |
| Recent advances in chitosan-based nanoparticulate pulmonary drug delivery N Islam, V Ferro Nanoscale 8 (30), 14341-14358, 2016 | 174 | 2016 |
| MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells PN Plummer, R Freeman, RJ Taft, J Vider, M Sax, BA Umer, D Gao, ... Cancer research 73 (1), 341-352, 2013 | 145 | 2013 |
| Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis V Ferro, L Liu, KD Johnstone, N Wimmer, T Karoli, P Handley, J Rowley, ... Journal of Medicinal Chemistry 55 (8), 3804-3813, 2012 | 143 | 2012 |
| The low molecular weight heparan sulfate-mimetic, PI-88, inhibits cell-to-cell spread of herpes simplex virus K Nyberg, M Ekblad, T Bergström, C Freeman, CR Parish, V Ferro, ... Antiviral research 63 (1), 15-24, 2004 | 136 | 2004 |
| The PG500 series: novel heparan sulfate mimetics as potent angiogenesis and heparanase inhibitors for cancer therapy K Dredge, E Hammond, K Davis, CP Li, L Liu, K Johnstone, P Handley, ... Investigational new drugs 28, 276-283, 2010 | 128 | 2010 |
| The development of inhibitors of heparanase, a key enzyme involved in tumour metastasis, angiogenesis and inflammation V Ferro, E Hammond, JK Fairweather Mini reviews in medicinal chemistry 4 (6), 693-702, 2004 | 124 | 2004 |
| Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance S Cochran, C Li, JK Fairweather, WC Kett, DR Coombe, V Ferro Journal of medicinal chemistry 46 (21), 4601-4608, 2003 | 123 | 2003 |
| A synthetic heparanase inhibitor reduces proteinuria in passive Heymann nephritis V Levidiotis, C Freeman, M Punler, P Martinello, B Creese, V Ferro, ... Journal of the American Society of Nephrology 15 (11), 2882-2892, 2004 | 114 | 2004 |
| Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening E Hammond, CP Li, V Ferro Analytical biochemistry 396 (1), 112-116, 2010 | 105 | 2010 |
| Preparation and anticoagulant activity of the phosphosulfomannan PI-88 G Yu, NS Gunay, RJ Linhardt, T Toida, J Fareed, DA Hoppensteadt, ... European journal of medicinal chemistry 37 (10), 783-791, 2002 | 105 | 2002 |
| Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor (PI-88) T Karoli, L Liu, JK Fairweather, E Hammond, CP Li, S Cochran, ... Journal of medicinal chemistry 48 (26), 8229-8236, 2005 | 102 | 2005 |
| Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth KD Johnstone, T Karoli, L Liu, K Dredge, E Copeman, CP Li, K Davis, ... Journal of medicinal chemistry 53 (4), 1686-1699, 2010 | 91 | 2010 |
| Large-scale preparation of the oligosaccharide phosphate fraction of Pichia holstii NRRL Y-2448 phosphomannan for use in the manufacture of PI-88 V Ferro, K Fewings, MC Palermo, C Li Carbohydrate research 332 (2), 183-189, 2001 | 90 | 2001 |
| Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 88 | 2022 |
| Carbohydrate–N-heterocyclic carbene metal complexes: Synthesis, catalysis and biological studies W Zhao, V Ferro, MV Baker Coordination Chemistry Reviews 339, 1-16, 2017 | 84 | 2017 |
| Use of sulfated linked cyclitols as heparan sulfate mimetics to probe the heparin/heparan sulfate binding specificity of proteins C Freeman, L Liu, MG Banwell, KJ Brown, A Bezos, V Ferro, CR Parish Journal of Biological Chemistry 280 (10), 8842-8849, 2005 | 80 | 2005 |
| A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus M Ekblad, B Adamiak, T Bergstrom, KD Johnstone, T Karoli, L Liu, V Ferro, ... Antiviral research 86 (2), 196-203, 2010 | 78 | 2010 |
